Results 141 to 150 of about 23,741 (299)

Neuropeptides as mediators of the early-life impact on the brain; implications for alcohol use disorders

open access: yesFrontiers in Molecular Neuroscience, 2012
The brain is constantly exposed to external and internal input and to function in an ever-changing environment we are dependent on processes that enable the brain to adapt to new stimuli.
Ingrid eNylander, Erika eRoman
doaj   +1 more source

Exposure to chronic mild stress prevents kappa opioid-mediated reinstatement of cocaine and nicotine place preference [PDF]

open access: yes, 2013
Stress increases the risk of drug abuse, causes relapse to drug seeking, and potentiates the rewarding properties of both nicotine and cocaine. Understanding the mechanisms by which stress regulates the rewarding properties of drugs of abuse provides ...
Al-Hasani, Ream   +2 more
core   +2 more sources

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

open access: yesFrontiers in Molecular Neuroscience, 2017
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj   +1 more source

Dopamine/Tyrosine Hydroxylase Neurons of the Hypothalamic Arcuate Nucleus Release GABA, Communicate with Dopaminergic and Other Arcuate Neurons, and Respond to Dynorphin, Met-Enkephalin, and Oxytocin

open access: yesJournal of Neuroscience, 2015
We employ transgenic mice with selective expression of tdTomato or cre recombinase together with optogenetics to investigate whether hypothalamic arcuate (ARC) dopamine/tyrosine hydroxylase (TH) neurons interact with other ARC neurons, how they respond ...
Xiaobing Zhang, A. N. van den Pol
semanticscholar   +1 more source

Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]

open access: yes, 1997
Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M.   +3 more
core  

Expression of Kisspeptin, Neurokinin B, and Dynorphin During Pubertal Development in Female Sheep [PDF]

open access: gold, 2021
Eliana G Aerts   +6 more
openalex   +1 more source

Individual differences in the neuropsychopathology of addiction. [PDF]

open access: yes, 2017
Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
core  

Dynorphin and its role in alcohol use disorder

open access: yesBrain Research, 2020
Anushree N. Karkhanis, R. Al-Hasani
semanticscholar   +1 more source

Social Isolation Induces Changes in the Monoaminergic Signalling in the Rat Medial Prefrontal Cortex

open access: yesCells
(1) Background: The effects of short-term social isolation during adulthood have not yet been fully established in rats behaviourally, and not at all transcriptomically in the medial prefrontal cortex (mPFC).
Vivien Csikós   +7 more
doaj   +1 more source

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