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Dynorphin receptor in the blood vessel
Neuropeptides, 1985 Using (3H)etorphine, (3H)E, in binding studies, the KD and Bmax for rabbit mesentery and aorta membrane preparations were 0.61 nM and 0.17 fmol/mg tissue respectively, while it was 0.30 nM and 12 fmol/mg tissue in the brain. The IC50 of dynorphin (1-13) (D1-13) for displacing (3H)E binding in the blood vessel was 20 +/- 2.8 nM (S,E,M,), while PLO17, D ...F Y, Sun, A Z, Zhangopenaire +2 more sourcesAntinociceptive profile of dynorphin in the rat
Life Sciences, 1983 Morphine, bremazocine, dynorphin(1-17) and two of its fragments (1-13) and (1-8) all increased nociceptive pressure thresholds in the rat after intracerebroventricular administration. Morphine also increased nociceptive heat thresholds in the hotplate test at similar dose-levels. In contrast, bremazocine and the dynorphins were totally inactive against A G, Hayes, M, Skingle, M B, Tyersopenaire +2 more sourcesDynorphin(1–10)amide: A potent and selective analog of dynorphin(1–13)
Life Sciences, 1982 Dynorphin(1-10)amide was more potent than Dynorphin(1-13) in inhibiting the twitch of the mouse vas deferens (IC50 of Dynorphin(1-10)amide = 0.3 nM and IC50 of Dynorphin (1-13) = 4.0 nM). Binding assays indicated that two opioid peptides had similar profiles in that they enhanced dihydromorphine (DHM) binding in picomolar concentrations but displaced ...S, Woo, J, Garzon, P, Sanchez-Blazquez, F C, Tulunay, J K, Chang, H H, Loh +5 moreopenaire +2 more sourcesDynorphins
2013 C. Renn Upchurch Sweeney, J. Rick Turner, J. Rick Turner, Chad Barrett, Ana Victoria Soto, William Whang, Carolyn Korbel, Sonia Matwin, Daniel Gorrin, Beth Schroeder, J. Rick Turner, Joost Dekker, Bonnie Levin, J. Rick Turner, Alefiyah Z. Pishori, John Grabowski, Samantha Yard, Kimberly Nelson, Ellen-ge Denton, Tatsuo Akechi, Monica Dowling, Brigitte M. Kudielka, Francine Kaufman, Luigi Meneghini, Luigi Meneghini, Kathleen Michael, David G. Marrero, Maartje de Wit, Jenny T. Wang, Jason S. Yeh, Janine Sanchez, J. Rick Turner, C. Renn Upchurch Sweeney, Annie T. Ginty, Kristen Salomon, Alvin Jin, Joel E. Dimsdale, Diane Dixon, Marijke Couck, Pamela S. King, Yori Gidron, Yori Gidron, Harry Prapavessis, Steven Gambert, Steven Gambert, J. Rick Turner, Lauren Zagorski, Wynne E. Norton, Kevin S. Masters, Lara Traeger, Nicole Brandt, Rachel Flurie, Brant P. Hasler, C. Andres Bedoya, Tamara Goldman Sher, Kathryn Noth, Jennifer Wessel, Edward L. Perkins, Howard Sollins, Debra Roter, Judith A. Hall, Laura Rodriguez-Murillo, Rany M. Salem, Michela Marinelli, Nicole Brandt, J. Rick Turner, Nicole Brandt, Faith S. Luyster, Ronald Goldberg, Valerie Sabol, Nina Rieckmann +70 moreopenaire +2 more sourcesDynorphin immunoreactivity in pituitary.
Advances in biochemical psychopharmacology, 1982 Tissue ir-dynorphin has been shown to be associated with three components separable by gel filtration. Similar components were found in both pituitary and brain, although there are differences in the relative amounts of each component in each tissue.B M, Cox, E R, Baer, A, Goldsteinopenaire +1 more sourceDynorphins
2010 Nicola Simola, Micaela Morelli, Tooru Mizuno, Suzanne H. Mitchell, Harriet de Wit, H. Valerie Curran, Celia J. A. Morgan, Stephan G. Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Lawrence H. Price, Grasielle C Kincheski, Leandro J Bertoglio, Antonio Padua Carobrez, Andrea Bari, Roshan Cools, Yogita Chudasama, Stefan Leucht, Yogita Chudasama, William Breitbart, Yesne Alici, Karl Mann, Falk Kiefer, Yesne Alici, William Breitbart, Michael M Morgan, M J Christie, Istvan Bitter, Eileen M. Joyce, Jonathan P Roiser, Darren R Christensen, Warren K. Bickel, Kenneth J. Rhodes, Peter Paul De Deyn, Debby Van Dam, Darrel J. Pemberton, Johannes Mosbacher, Thomas Steckler, Alyson J Bond, Alex Hofer, Stefan Leucht, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Irwin Lucki, Fadi T. Maalouf, David A. Brent, David A. Brent, Fadi Maalouf, Alex Hofer, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Huaiyu Yang, George I. Papakostas, Andrew Young, Gabriele Fischer, Annemarie Unger, Linda P Spear, Linda P Spear, Mohammed Shoaib, Emma Childs, Britta Hahn, Peter Boeijinga, Martine Cador, David S Tait, Verity J. Brown, Martine Cador, David Baldwin, Yavin Shaham, Sunila G Nair, Yavin Shaham, Sunila G Nair, Matthew I Palmatier, Rick A Bevins, Peter Riederer, Siegfried Hoyer, Mark Geyer, Anthony Absalom, David Menon, Joseph Zohar, Stephen C Fowler, James Winslow, Kim Wolff, Bankole A. Johnson, Martina de Zwaan, Alyson J Bond, Angela Roberts, Anthony R Isles, Lawrence S. Wilkinson, Anthony R Isles, Lawrence S. Wilkinson, Rosa M M de Almeida, Klaus A. Miczek, Eric Nestler, Naheed (Max) Mirza, Bankole A Johnson, Joseph H Friedman, István Bitter, Michael Minzenberg, Lawrence H. Price, Ashwini Padhi, Naomi Fineberg, Michael M Morgan, MacDonald J. Christie, Lawrence H. Price, Joris C. Verster, Bernard Le Foll, Marilyn E Carroll, Peter A Santi, Ronald F Mucha, Ian P. Stolerman, Richard W Foltin, Michael Minzenberg, Christoph Hiemke, Luis Stinus, Stéphanie Caillé, Martine Cador, Yavin Shaham, John R Mantsch, Ronald F Mucha, Kim Wolff, Anthony L. Riley, Steve Kohut, Brian E. Leonard, Joseph Zohar, R. Andrew Chambers, Gail Winger, Mei-Chuan Ko, James H Woods, Huaiyu Yang, George I. Papakostas, Michael M Morgan, MacDonald J. Christie, Seiya Miyamoto, Thomas R. E. Barnes, Kieran O’Malley, Luis Stinus, Stéphanie Caillé, Martine Cador, David J. Hellerstein, Thomas R. E. Barnes +141 moreopenaire +1 more source
