Results 1 to 10 of about 13,445 (168)

Physical activity moderates the relationship between hot flashes and arterial wave reflection in perimenopausal females

open access: yesPhysiological Reports, Volume 14, Issue 10, May 2026.
Abstract Subclinical CVD risk factors are associated with hot flashes (HF). Habitual physical activity (PA) reduces CVD risk in part due to effects on blood vessel characteristics. The objective was to evaluate associations between arterial wave reflection (WR), HFs, and PA in perimenopausal people and determine whether PA moderates the relationship ...
Tint Tha Ra Wun   +5 more
wiley   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Intra-Testicular Signals Regulate Germ Cell Progression and Production of Qualitatively Mature Spermatozoa in Vertebrates [PDF]

open access: yes, 2014
Spermatogenesis, a highly conserved process in vertebrates, is mainly under the hypothalamic-pituitary control, being regulated by the secretion of pituitary gonadotropins, FSH and LH, in response to stimulation exerted by Gonadotropin Releasing Hormone (
Gilda Cobellis   +6 more
core   +2 more sources

Hyperoside Modulates the Estrogen‐PI3K/VEGF Axis to Ameliorate Oxidative Damage‐Induced Inhibition of Bone Formation in MC3T3‐E1 Cells

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
This study explores the potential of hyperoside to activate the estrogen‐PI3K/VEGF axis, thereby suppressing oxidative stress and enhancing osteogenic differentiation to mitigate osteoporosis. The initial proposal of the estrogen‐PI3K/VEGF signaling pathway axis as a potential therapeutic approach for osteoporosis.
Shuo Wang   +8 more
wiley   +1 more source

KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]

open access: yes, 2011
KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
De Caro, Raffaele   +6 more
core  

Low Degree of Overlap Between Kisspeptin, Neurokinin B, and Dynorphin Immunoreactivities in the Infundibular Nucleus of Young Male Human Subjects Challenges the KNDy Neuron Concept. [PDF]

open access: yes, 2012
Previous immunohistochemical and in situ hybridization studies of sheep, goats, and rodents indicated that kisspeptin (KP), neurokinin B (NKB), and dynorphin A (DYN) are extensively colocalized in the hypothalamic arcuate nucleus, thus providing a basis ...
Borsay, Beáta Ágnes   +7 more
core   +1 more source

The Transcription Factors Six3 and Six6 in Neuromedin‐S Neurons Differentially Affect Circadian Rhythms

open access: yesJournal of Neuroscience Research, Volume 104, Issue 4, April 2026.
Six3 and Six6 are necessary for the development of the suprachiasmatic nucleus (SCN), and both remain expressed after SCN neurogenesis. We implemented a Neuromedin‐S (NMS)‐cre mouse model to conditionally knockout either Six3 or Six6 from the SCN to determine the post‐proliferative roles of these transcription factors in hypothalamic and circadian ...
Brooke M. Van Loh   +11 more
wiley   +1 more source

Hyperprolactinemia-induced ovarian acyclicity is reversed by kisspeptin administration [PDF]

open access: yes, 2012
Hyperprolactinemia is the most common cause of hypogonadotropic anovulation and is one of the leading causes of infertility in women aged 25-34. Hyperprolactinemia has been proposed to block ovulation through inhibition of GnRH release.
Alain Caraty   +10 more
core   +5 more sources

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink   +9 more
wiley   +1 more source

Follicle size on day of trigger most likely to yield a mature oocyte [PDF]

open access: yes, 2018
Funding: MRC, BBSRC and NIHR and supported by the NIHR/Wellcome Trust Imperial Clinical Research Facility and Imperial Biomedical Research Centre.Objective: To identify follicle sizes on the day of trigger most likely to yield a mature oocyte following ...
Alexander N. Comninos   +12 more
core   +3 more sources

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