Results 31 to 40 of about 6,216 (180)
Expression of Kisspeptin 1 in the Brain of the Adult Sea Lamprey Petromyzon marinus
Life, 2021 Kisspeptin peptides play major roles in the regulation of reproduction and puberty onset in mammals. While most mammals only have one kisspeptin gene, other jawed vertebrates present two or three genes. Recent data also revealed the presence of two genes
Daniel Sobrido-Cameán +4 more
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Quantification of rat kisspeptin using a novel radioimmunoassay.
PLoS ONE, 2014 Kisspeptin is a hypothalamic peptide hormone that plays a pivotal role in pubertal onset and reproductive function. Previous studies have examined hypothalamic kisspeptin mRNA expression, either through in situ hybridisation or real-time RT-PCR, as a ...
James S Kinsey-Jones +6 more
doaj +1 more source
Frontiers in Veterinary Science, 2018 Kisspeptin is a neuropeptide that governs the reproductive axis upstream to GnRH. We wanted to study whether kisspeptin modulates plasma LH and FSH levels and ovarian follicular dynamics in buffaloes and whether kisspeptin can be used for fixed time ...
Vishalkumar Pottapenjera +8 more
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The Emerging Role(s) for Kisspeptin in Metabolism in Mammals
Frontiers in Endocrinology, 2018 Kisspeptin was initially identified as a metastasis suppressor. Shortly after the initial discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with kisspeptin acting as a neurotransmitter via the kisspeptin receptor ...
Andrew Wolfe, Mehboob A. Hussain
doaj +1 more source
Reproductive Biology and Endocrinology, 2022 Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for the placentation and establishment of a successful pregnancy.
Lanlan Fang +7 more
doaj +1 more source
Role of Kisspeptin and Neurokinin B in Puberty in Female Non-Human Primates
Frontiers in Endocrinology, 2018 In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty.
Ei Terasawa +4 more
doaj +1 more source
The Journal of Reproduction and Development, 2020 The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the ...
Kana IKEGAMI +15 more
doaj +1 more source
Kisspeptin Signaling in the Brain [PDF]
Endocrine Reviews, 2009 Abstract Kisspeptin (a product of the Kiss1 gene) and its receptor (GPR54 or Kiss1r) have emerged as key players in the regulation of reproduction. Mutations in humans or genetically targeted deletions in mice of either Kiss1 or Kiss1r cause profound hypogonadotropic hypogonadism.
Amy E, Oakley +2 more
openaire +2 more sources
The Role of Kisspeptin in the Control of the Hypothalamic-Pituitary-Gonadal Axis and Reproduction
Frontiers in Endocrinology, 2022 The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given people a novel understanding of the neuroendocrine regulation in human reproduction.
Qinying Xie +8 more
doaj +1 more source
BMC Biology, 2022 Background Kisspeptins are neuropeptides that regulate reproductive maturation in mammals via G-protein-coupled receptor-mediated stimulation of gonadotropin-releasing hormone secretion from the hypothalamus.
Nayeli Escudero Castelán +10 more
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