Results 11 to 20 of about 13,445 (168)

Expressions of Kisspeptin System and Ki-67 in the Reproductive Tissues of Cyclic Bitches. [PDF]

Reprod Domest Anim
ABSTRACT Kisspeptin is a peptide that plays a pivotal role in the central regulation of gonadotropins. It is regarded as a key regulator of reproductive processes, including follicular and luteal development and endometrial remodelling. The objective of this study was to investigate the expression of KISS1, its receptor KISS1R and the proliferation ...
Korkmaz Ağaoğlu Ö, Ağaoğlu AR, Özmen Ö, Bozkurt G, Taşan Ş.   +4 more
europepmc   +2 more sources

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Santos B, dos Anjos Cordeiro J, Santos L, Oliveira C, Alvarez M, Rodrigues N, Lopez‐Tello J, Sferruzzi‐Perri A, Serakides R, Silva J.   +9 more
europepmc   +2 more sources

GABA receptor modulation of arcuate kisspeptin neuron bursting and synchronization activity in female mice [PDF]

J Neuroendocrinol
Abstract The arcuate nucleus kisspeptin (ARNKISS) neurons intermittently synchronize their activity to operate as the GnRH pulse generator and drive pulsatile reproductive hormone secretion in mammals. Although ARNKISS neurons are known to receive various GABAergic inputs, the effects of GABAA and GABAB receptor modulation on their ability to ...
Eddleston T, Morris P, Herbison A.
europepmc   +2 more sources

Neuroendocrine plasticity and crosstalk in pubertal development. [PDF]

J Neuroendocrinol
Abstract Puberty is a critical developmental stage during which individuals acquire the capacity for sexual reproduction. This transition involves a series of complex biological events primarily orchestrated by the activation of the hypothalamo–pituitary–gonadal (HPG) axis.
Elias CF, Han X, Garcia-Galiano D, Sáenz de Miera C.   +3 more
europepmc   +2 more sources

VGF changes during the estrous cycle: a novel endocrine role for TLQP peptides? [PDF]

, 2014
Although the VGF derived peptide TLQP-21 stimulates gonadotropin-releasing hormone (GnRH) and gonadotropin secretion, available data on VGF peptides and reproduction are limited.
Brancia C, Cocco C, D'Amato F, Ferri G-L, Noli B   +4 more
core   +22 more sources

Hyperalgesic activity of kisspeptin in mice. [PDF]

Molecular Pain, 2011
BACKGROUND: Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of the spinal ...
Biagioni, Francesca, Biasiotta, Antonella, Chiechio, Santina, Colledge, William H, Copani, Agata, Cruccu, Giorgio, Nicoletti, Ferdinando, Sortino, Maria Angela, Spampinato, Simona, Trabucco, Angela   +9 more
core   +7 more sources

Kisspeptin/Kisspeptin Receptor System in the Ovary [PDF]

Frontiers in Endocrinology, 2018
Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating ovulation in sexually mature females via the central control of the hypothalamic-pituitary-gonadal axis. Recent studies have shown that kisspeptin and its receptor kisspeptin receptor (KISS1R) are expressed in the mammalian ovary.
Kai-Lun Hu, Hongcui Zhao, Hsun-Ming Chang, Yang Yu, Jie Qiao   +4 more
openaire   +3 more sources

Kisspeptin and fertility [PDF]

Journal of Endocrinology, 2010
The kisspeptins are a family of peptide hormones, which in recent years have been shown to play a critical role in the regulation of the hypothalamic-pituitary-gonadal axis, thus in turn influencing fertility and reproduction. This review examines the physiological role of kisspeptin and the kisspeptin receptor in the control of gonadotrophin and ...
Saira, Hameed, Channa N, Jayasena, Waljit S, Dhillo   +2 more
openaire   +2 more sources

Anorexia nervosa and reproduction: connecting brain to gonads [PDF]

, 2020
Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina, Fica, Simona, Poterasu, Mihaela, Rowland, David L.   +3 more
core   +2 more sources

MOLECULAR EVOLUTION OF GPCRS: Kisspeptin/kisspeptin receptors [PDF]

Journal of Molecular Endocrinology, 2014
Following the discovery of kisspeptin (Kiss) and its receptor (GPR54 or KissR) in mammals, phylogenetic studies revealed up to three Kiss and four KissR paralogous genes in other vertebrates. The multiplicity of Kiss and KissR types in vertebrates probably originated from the two rounds of whole-genome duplication (1R and 2R) that occurred in early ...
Pasquier, Jérémy, Kamech, Nédia, Lafont, Anne-Gaelle, Vaudry, Hubert, Rousseau, Karine, Dufour, Sylvie   +5 more
openaire   +4 more sources