Results 11 to 20 of about 9,905 (169)
Kisspeptin/Kisspeptin Receptor System in the Ovary [PDF]
Frontiers in Endocrinology, 2018 Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating ovulation in sexually mature females via the central control of the hypothalamic–pituitary–gonadal axis.
Yang Yu +4 more
core +4 more sources
Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin-releasing hormone neurons in female mice. [PDF]
J NeuroendocrinolAbstract Kisspeptin neurons in the rostral hypothalamus are hypothesized to initiate preovulatory gonadotropin‐releasing hormone (GnRH) surges by causing estradiol‐dependent activation of GnRH neuron action potential firing and subsequent GnRH release.
Starrett JR +4 more
europepmc +2 more sources
Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions. [PDF]
J NeuroendocrinolAbstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Rose L, Kauffman AS.
europepmc +2 more sources
The translational use of Kisspeptin and kisspeptin receptor agonists in humans [PDF]
, 2020 Kisspeptin is a neuropeptide that is known to be a critical regulator of hypothalamic gonadotrophin releasing hormone (GnRH). Physiological studies of kisspeptin have examined the effects of different kisspeptin isoforms (Kisspeptin-10, kisspeptin-54) on
Eng, Pei Chia
core +3 more sources
Kisspeptin and seasonality in sheep [PDF]
Peptides, 2009 International audienceSheep are seasonal breeders, experiencing a period of reproductive quiescence during spring and early summer. During the non-breeding period, kisspeptin expression in the arcuate nucleus is markedly reduced.
Smith, J.T. +4 more
core +4 more sources
, 2013 Kisspeptin is now known to be an important regulator of the hypothalamic-pituitary-gonadal axis and is the target of a range of regulators, such as steroid hormone feedback, nutritional and metabolic regulation. Kisspeptin binds to its cognate receptor,
Roseweir, Antonia Kathryn +3 more
core +3 more sources
Kisspeptin and Glucose Homeostasis
Seminars in Reproductive Medicine, 2019 Kisspeptin has well-established critical roles in the control of reproduction and fertility. Recently, evidence has emerged that suggests kisspeptin may have additional roles in the regulation of glucose homeostasis. Conflicting reports on the effects of
Izzi-Engbeaya, Chioma +2 more
core +4 more sources
The role of kisspeptin in sexual behavior [PDF]
Seminars in Reproductive Medicine, 2019 peer reviewedSexual behavior is essential for the perpetuation of a species. In female rodents, mate preference and lordosis behavior depend heavily on the integration of olfactory cues into the neuroendocrine brain, yet its underlying neural circuits ...
Brock, Olivier +6 more
core +6 more sources
Kisspeptin and Endometriosis—Is There a Link?
Journal of Clinical MedicineThis article presents a narrative review that explores the potential link between kisspeptin—a key regulator of the hypothalamic-pituitary-gonadal axis—and the pathogenesis of endometriosis.
Agata Nowicka +5 more
core +3 more sources
Kisspeptin receptor in GtoPdb v.2023.1 [PDF]
, 2023 The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [11]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides ...
Pawson, Adam J +7 more
core +1 more source