Results 1 to 10 of about 3,911 (126)

The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model [PDF]

Scientific Reports, 2023
AbstractUremic cardiomyopathy is characterized by diastolic dysfunction, left ventricular hypertrophy (LVH), and fibrosis. Dysregulation of the kisspeptin receptor (KISS1R)-mediated pathways are associated with the development of fibrosis in cancerous diseases.
Dinh, Hoa, Kovacs, Zsuzsanna Z.A., Marvanykovi, Fanni, Kis, Merse, Kupecz, Klaudia, Szucs, Gergo, Freiwan, Marah, Lauber, Gulsum Yilmaz, Acar, Eylem, Siska, Andrea, Ibos, Katalin Eszter, Bodnar, Eva, Kriston, Andras, Kovacs, Ferenc, Horvath, Peter, Foldesi, Imre, Cserni, Gabor, Podesser, Bruno K., Pokreisz, Peter, Kiss, Attila, Dux, Laszlo, Csabafi, Krisztina, Sarkozy, Marta   +22 more
openaire   +6 more sources

Interaction of central kisspeptin with melanocortin, GABAergic, corticotrophin, and NPY systems on food intake in chickens [PDF]

The Iranian Journal of Veterinary Science and Technology, 2022
Kisspeptin is a key component of reproduction that can directly affect food intake in mammals. There is evidence suggesting that melanocortin, GABA, corticotrophin, and neuropeptide Y (NPY), have a mediatory role in reward; however, how these substances ...
Ahmadreza Kord, Bita Vazir, Morteza Zendedel kheybari, Vahab Babapour, Ahmad Asghari   +4 more
doaj   +1 more source

Hot flashes: Why? [PDF]

Romanian Medical Journal, 2021
Hot flashes (HF), transitory episodes of erythema, heat sensation, anxiety followed by chills, are described in carcinoid syndrome, mastocytosis, medullary thyroid cancer, hyperthyroidism, pheochromocytoma, alcohol consumption, side effects of drugs, and
Florica Sandru, Mihai Cristian Dumitrascu, Eugenia Petrova, Anda Dumitrascu, Claudiu Tupea, Mara Carsote, Adina Ghemigian, Ana Valea   +7 more
doaj   +1 more source

Neuroanatomical evidence that kisspeptin directly regulates isotocin and vasotocin neurons. [PDF]

PLoS ONE, 2013
Neuropeptide kisspeptin has been suggested to be an essential central regulator of reproduction in response to changes in serum gonadal steroid concentrations.
Shinji Kanda, Yasuhisa Akazome, Yuta Mitani, Kataaki Okubo, Yoshitaka Oka   +4 more
doaj   +1 more source

Anomalous Temperature Interdicts the Reproductive Activity in Fish: Neuroendocrine Mechanisms of Reproductive Function in Response to Water Temperature

Frontiers in Physiology, 2022
Fish are poikilotherm and small changes in water temperature can greatly affect physiological processes including reproduction, which is regulated by complex neuroendocrine mechanisms that respond to climatic events.
Md. Mahiuddin Zahangir, Md. Mahiuddin Zahangir, Mohammad Lutfar Rahman, Mohammad Lutfar Rahman, Hironori Ando   +4 more
doaj   +1 more source

Nonstop mutation in the Kisspeptin 1 receptor (KISS1R) gene causes normosmic congenital hypogonadotropic hypogonadism [PDF]

Journal of Assisted Reproduction and Genetics, 2019
Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disorder mostly characterized by gonadotropins release and/or action deficiencies. Both isolated (idiopathic hypogonadotropic hypogonadism) and syndromic (Kallmann) forms are identified depending on the olfactory ability.
Mariam Moalla, Faten Hadj Kacem, Abdullah Fahad Al-Mutery, Mona Mahfood, Nabila Mejdoub-Rekik, Mohamed Abid, Mouna Mnif-Feki, Hassen Hadj Kacem   +7 more
openaire   +2 more sources

Effects of Ovarian Transplant on Anti-Müllerian Hormone, Kisspeptin-1, and Kisspeptin-1 Receptor Levels in Rats

Experimental and Clinical Transplantation, 2020
Information is scarce on levels of kisspeptin-1 and the kisspeptin-1 receptorin females after ovarian transplant. In this study, our aim was to explore serum estradiol, anti-Müllerian hormone, kisspeptin-1, and kisspeptin receptor levels, along with kisspeptin-1-positive cell density, in ovaries from rats after ovarian transplant.For this study, 28 ...
Risvanli, Ali, Ocal, Halis, Timurkaan, Necati, Ipek, Pinar, Cevik, Aydin, Seker, Ibrahim   +5 more
openaire   +4 more sources

GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. [PDF]

PLoS ONE, 2011
Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands for a G protein-coupled receptor 54 (GPR54). Previous findings have shown that KISS1 acts as a metastasis suppressor in numerous cancers in humans. However, recent
Mateusz Zajac, Jeffrey Law, Dragana Donna Cvetkovic, Macarena Pampillo, Lindsay McColl, Cynthia Pape, Gianni M Di Guglielmo, Lynne M Postovit, Andy V Babwah, Moshmi Bhattacharya   +9 more
doaj   +1 more source

The Role of Genetics in Central Precocious Puberty: Confirmed and Potential Neuroendocrine Genetic and Epigenetic Contributors and Their Interactions with Endocrine Disrupting Chemicals (EDCs)

Endocrines, 2022
Despite the growing prevalence of central precocious puberty (CPP), most cases are still diagnosed as “idiopathic” due to the lack of identifiable findings of other diagnostic etiology.
Andrea Mucci, Ethel Clemente
doaj   +1 more source

Differential stimulation of insulin secretion by GLP-1 and Kisspeptin-10. [PDF]

PLoS ONE, 2014
β-cells in the pancreatic islet respond to elevated plasma glucose by secreting insulin to maintain glucose homeostasis. In addition to glucose stimulation, insulin secretion is modulated by numerous G-protein coupled receptors (GPCRs).
Tara A Schwetz, Christopher A Reissaus, David W Piston   +2 more
doaj   +1 more source