Results 11 to 20 of about 108,912,939 (192)

Hyperalgesic activity of kisspeptin in mice [PDF]

Molecular Pain, 2011
Background Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of the spinal ...
Spampinato Simona, Trabucco Angela, Biasiotta Antonella, Biagioni Francesca, Cruccu Giorgio, Copani Agata, Colledge William H, Sortino Maria, Nicoletti Ferdinando, Chiechio Santina   +9 more
doaj   +5 more sources

Biological Significance of Kisspeptin–Kiss 1 Receptor Signaling in the Habenula of Teleost Species [PDF]

Frontiers in Endocrinology, 2018
Kisspeptin is a neuropeptide, encoded by kisspeptin 1 (KISS1)/Kiss1 gene, which primarily acts as the regulator of reproductive functions via its receptor, kisspeptin receptor (KissR) in vertebrates.
Satoshi Ogawa, Ishwar S. Parhar
doaj   +3 more sources

Kisspeptin/GPR54 System: What Do We Know About Its Role in Human Reproduction?

Cellular Physiology and Biochemistry, 2018
Kisspeptin is involved in the control of human reproduction bridging the gap between the sex steroid levels and feedback mechanisms that control the gonadotropin releasing hormone (GnRH) secretion; however, studies considering this peptide and ...
Camila M. Trevisan, Erik Montagna, Renato de Oliveira, Denise M. Christofolini, Caio P. Barbosa, Keith A. Crandall, Bianca  Bianco   +6 more
doaj   +3 more sources

Oestrogen Induces Rhythmic Expression of the Kisspeptin-1 Receptor GPR54 in Hypothalamic Gonadotrophin-Releasing Hormone-Secreting GT1-7 Cells [PDF]

Journal of Neuroendocrinology, 2011
Oestrogen-stimulated preovulatory gonadotrophin surges are temporally regulated in a way that remains not fully understood. Mammalian ovulation requires surges of gonadotrophin-releasing hormone (GnRH), released from specialised neurones in the hypothalamus. Surge regulation is mediated by ovarian oestrogen (17 β-oestradiol; E(2) ) feedback-acting as a
K J, Tonsfeldt, C P, Goodall, K L, Latham, P E, Chappell   +3 more
openaire   +3 more sources

Kisspeptin Antagonists Reveal Kisspeptin 1 and Kisspeptin 2 Differential Regulation of Reproduction in the Teleost, Morone saxatilis1 [PDF]

Biology of Reproduction, 2015
The importance of kisspeptin in regulating vertebrate reproduction has been well established, but the exact mechanism continues to unfold. Unlike mammals, many lower vertebrates possess a dual kisspeptin system, Kiss1 and Kiss2. To decipher the roles
N. Zmora, J. Stubblefield, Ten-Tsao Wong, B. Levavi-Sivan, R. Millar, Y. Zohar   +5 more
semanticscholar   +2 more sources

Expression of the anti-Mullerian hormone, kisspeptin 1, and kisspeptin 1 receptor in polycystic ovary syndrome and controlled ovarian stimulation rat models

Bosnian Journal of Basic Medical Sciences, 2019
Polycystic ovary syndrome represents a significant cause of female infertility. The aim of this study was to investigate the expression of anti-Mullerian hormone (AMH), kisspeptin 1 (KISS-1), and kisspeptin 1 receptor (KISS1r) in rat models of polycystic ovary syndrome (PCOS) and controlled ovarian stimulation (COS).
Ali Risvanli, Halis Ocal, Necati Timurkaan, Pınar Ipek, Ibrahim Seker, Burak Karabulut   +5 more
openaire   +5 more sources

Expression of a functional g protein-coupled receptor 54-kisspeptin autoregulatory system in hypothalamic gonadotropin-releasing hormone neurons.

Molecular Endocrinology, 2007
The G protein-coupled receptor 54 (GPR54) and its endogenous ligand, kisspeptin, are essential for activation and regulation of the hypothalamic-pituitary-gonadal axis.
Samuel D. Quaynor, Lian Hu, P. Leung, Hao Feng, N. Mores, L. Krsmanovic, K. Catt   +6 more
semanticscholar   +2 more sources

Serum Spexin, Kisspeptin-1, Substance P, and Neurokinin-1 Receptor Levels in Hyperemesis Gravidarum: A Prospective Paired Follow-Up Study

Cumhuriyet Science Journal
Hyperemesis gravidarum (HG) is characterized by severe nausea and vomiting during pregnancy and may adversely affect both maternal health and fetal development. This study aimed to investigate serum spexin, kisspeptin-1, substance P, and neurokinin-1 receptor levels, which were hypothesized to be associated with HG.
Ayça Taş, Dilay Karademir, Tugba Agbektas, Zuhal Tunçbilek, Gülcihan Cinar Kaya, Yavuz Siliğ   +5 more
openaire   +2 more sources

Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin-releasing hormone neurons in female mice. [PDF]

J Neuroendocrinol
Abstract Kisspeptin neurons in the rostral hypothalamus are hypothesized to initiate preovulatory gonadotropin‐releasing hormone (GnRH) surges by causing estradiol‐dependent activation of GnRH neuron action potential firing and subsequent GnRH release.
Starrett JR, Chen X, Krasner D, Phillips CD, Moenter SM.   +4 more
europepmc   +2 more sources

Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions. [PDF]

J Neuroendocrinol
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Rose L, Kauffman AS.
europepmc   +2 more sources