Results 41 to 50 of about 108,912,939 (192)
Interactions of GPR54 and GPR147 receptors with RF-amide ligands [PDF]
Includes bibliographical references.G protein-coupled receptors play a key role in cellular signaling by transducing extracellular signals via G proteins to elicit intracellular responses.
Hendrikse, Megan
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Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Herczeg, László +11 more
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Co‐expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats
Purpose Hypothalamic kisspeptin neurons are considered to play a critical role in regulating mammalian reproduction and integrating humoral and neuronal inputs that control gonadotropin‐releasing hormone (GnRH)/gonadotropin release.
Assadullah +7 more
doaj +1 more source
Kisspeptin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [9]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides ...
Maguire, Janet J. +2 more
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Additional file 7. CLuster Analysis of Sequences (CLANS) of receptors identified by BLAST analysis of bilaterian proteomes using human and S. purpuratus kisspeptin-type receptors as queries.
Scrivens, James H. +16 more
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The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates
Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: 1. gonadotropin-inhibitory hormone (GnIH), 2. neuropeptide FF (NPFF) 3. pyroglutamylated RFamide peptide (QRFP), 4. prolactin-releasing peptide (PrRP)
Maurice Richard Elphick +1 more
doaj +1 more source
Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands
Kisspeptin is a member of the RFamide neuropeptide family that is implicated in gonadotropin secretion. Because kisspeptin-GPR54 signaling is implicated in the neuroendocrine regulation of reproduction, GPR54 ligands represent promising therapeutic ...
Kei-ichiro Maeda (479344) +15 more
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Neurokinin B (NKB) and its cognate receptor (NK3R) are emerging as important components of the neuroendocrine regulation of reproduction. Unlike mammalian tac3, which encodes only one mature peptide (namely NKB), two mature peptides are predicted for ...
Naama Mizrahi +5 more
doaj +1 more source
Kisspeptin neurons located in the arcuate nucleus (ARN) coexpress dynorphin and neurokinin B (NKB) and may interact to influence gonadotropin secretion.
de Croft, Simon +2 more
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Kisspeptin Regulation of Neuronal Activity throughout the Central Nervous System [PDF]
Kisspeptin signaling at the gonadotropin-releasing hormone (GnRH) neuron is now relatively well characterized and established as being critical for the neural control of fertility.
Allan E. Herbison, Xinhuai Liu
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