Results 51 to 60 of about 6,714 (159)

KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]

, 2011
KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
De Caro, Raffaele, Fenu, Grazia, Macchi, Veronica, Malendowicz, Ludwik K., Montella, Andrea Costantino Mario, Porzionato, Andrea, Ruciński, Marcin   +6 more
core  

Design and synthesis of fluorescent probes for GPR54. [PDF]

, 2014
Kisspeptins are neuropeptides that induce the secretion of gonadotropin-releasing hormone via the activation of the cognate receptor, G-protein coupled receptor 54 (GPR54).
Fujii, Nobutaka, Hirasawa, Akira, Ieda, Nahoko, Kaneda, Masato, Maeda, Kei-ichiro, Misu, Ryosuke, Ohno, Hiroaki, Oishi, Shinya, Tsukamura, Hiroko, Uenoyama, Yoshihisa   +9 more
core   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in male mice [PDF]

, 2018
Restraint stress is a psychosocial stressor that suppresses reproductive status, including LH pulsatile secretion, but the neuroendocrine mechanisms underlying this inhibition remains unclear.
Hughes, Jessica K, Kauffman, Alexander S, Parra, Ruby A, Volk, Katrina M, Yang, Jennifer A   +4 more
core   +1 more source

Hyperoside Modulates the Estrogen‐PI3K/VEGF Axis to Ameliorate Oxidative Damage‐Induced Inhibition of Bone Formation in MC3T3‐E1 Cells

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
This study explores the potential of hyperoside to activate the estrogen‐PI3K/VEGF axis, thereby suppressing oxidative stress and enhancing osteogenic differentiation to mitigate osteoporosis. The initial proposal of the estrogen‐PI3K/VEGF signaling pathway axis as a potential therapeutic approach for osteoporosis.
Shuo Wang, Wei Feng, Xueqin Feng, Peitong Wu, Nanxi Zhang, Xiaoqian Yang, Yawen Li, Chunnan Li, Jiaming Sun   +8 more
wiley   +1 more source

The Transcription Factors Six3 and Six6 in Neuromedin‐S Neurons Differentially Affect Circadian Rhythms

Journal of Neuroscience Research, Volume 104, Issue 4, April 2026.
Six3 and Six6 are necessary for the development of the suprachiasmatic nucleus (SCN), and both remain expressed after SCN neurogenesis. We implemented a Neuromedin‐S (NMS)‐cre mouse model to conditionally knockout either Six3 or Six6 from the SCN to determine the post‐proliferative roles of these transcription factors in hypothalamic and circadian ...
Brooke M. Van Loh, Geneva A. Dunn, Lauren E. Chun, Meera M. Patel, Nay Chi P. Naing, Duong Nguyen, Alexandra M. Yaw, Michael R. Gorman, Jessica Cassin, Pamela L. Mellon, Hanne M. Hoffmann, Karen J. Tonsfeldt   +11 more
wiley   +1 more source

Lack of functional GABA receptors alters Kiss1 , Gnrh1 and Gad1 mRNA expression in the medial basal hypothalamus at postnatal day 4 [PDF]

, 2013
Background/Aims: Adult mice lacking functional GABAB receptors (GABAB1KO) show altered Gnrh1 and Gad1 expressions in the preoptic area-anterior hypothalamus (POA-AH) and females display disruption of cyclicity and fertility.
Bettler, B., Catalano, P. N., Di Giorgio, N. P., Gonzalez, B., Kauffman, A. S., Libertun, C., Lopez, G. C., Lopez, P. V., Lux-Lantos, V. A., Rulli, S. B., Semaan, S. J., Somoza, G. M.   +11 more
core   +2 more sources

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink, Karolina Afors, Luis Bahamondes, Alessandra Graziottin, Deborah Bateson, Teresa Bombas, Yutaki Osuga, Santiago Palacios, Carolyn L. Westhoff, Kristina Gemzell‐Danielsson   +9 more
wiley   +1 more source

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos, Jeane Martinha dos Anjos Cordeiro, Luciano Cardoso Santos, Cleisla Souza Oliveira, Maria Clara Pascoal Santos Alvarez, Natália Panhoca Rodrigues, Jorge Lopez‐Tello, Amanda N. Sferruzzi‐Perri, Rogéria Serakides, Juneo Freitas Silva   +9 more
wiley   +1 more source

Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice. [PDF]

, 2017
The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion. Kiss1-syntheizing neurons reside primarily in the hypothalamic anteroventral periventricular (AVPV/PeN) and arcuate (ARC) nuclei.
Chahal, Navi, Kauffman, Alexander S, Liaw, Reanna B, Parra, Ruby A, Rouse, Melvin L, Stephens, Shannon BZ, Tolson, Kristen P   +6 more
core   +1 more source