Results 71 to 80 of about 108,912,939 (192)
Sex Differences in the Brain Transcriptomes of Adult Blue Gourami Fish (Trichogaster trichopterus)
Blue gourami (gourami, Trichogaster trichopterus) is a model for labyrinth fishes (Anabantoidei) adapted to partial air breathing. Its reproductive endocrinology has been extensively studied, and transcriptomic sex differences in the gonads were ...
Gad Degani, Ari Meerson
doaj +1 more source
Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Zsolt Liposits +3 more
core +1 more source
Abstract To describe clinical presentation and genetic findings in a cohort of infants with congenital hypogonadotropic hypogonadism (CHH) diagnosed before 2 years of age. From a large cohort of patients who underwent next‐generation sequencing (NGS) for CHH between 2019 and 2025, we identified all patients tested at ≤2 years of age.
Karine Aouchiche +16 more
wiley +1 more source
Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty [PDF]
Objective: Puberty is a key developmental phenomenon highly sensitive to metabolic modulation. Worrying trends of changes in the timing of puberty have been reported in humans.
Silvia Leon +34 more
core +1 more source
Sustained induction of PMOS‐like phenotype in mice exposed to letrozole in drinking water
Abstract Polyendocrine metabolic ovarian syndrome (PMOS; formerly polycystic ovary syndrome) is the most common endocrinopathy affecting women of reproductive age, characterized by ovarian dysfunction and hyperandrogenism, with metabolic disturbances including insulin resistance and obesity also present for 50% of PMOS patients.
Kennedy A. Stevenson +3 more
wiley +1 more source
Placental mRNA Expression of Neurokinin B Is Increased in PCOS Pregnancies with Female Offspring
Current research suggests that polycystic ovary syndrome (PCOS) might originate in utero and implicates the placenta in its pathogenesis. Kisspeptin (KISS1) and neurokinin B (NKB) are produced by the placenta in high amounts, and they have been ...
Georgios K. Markantes +6 more
doaj +1 more source
Introduction. The mammalian reproductive system is a complex neuroendocrine mechanism in which the hypothalamic-pituitary-gonadal axis plays a leading role. Stress suppresses the functioning of the kisspeptin system.
V. Golts +11 more
semanticscholar +1 more source
Regulation of Kisspeptin-expressing Neurons and Stimulatory Mode of Action of Kisspeptin in Immortalized Hypothalamic Cell Models [PDF]
Fertility is a highly regulated process dependent on the orchestration of hypothalamic neuropeptides and peripheral hormones, which converge on GnRH neurons in the HPG axis.
Friedman, Zoey
core
The Role and Mechanism of Incretins in Gynaecologic Diseases
This review outlines the mechanisms of incretins in polycystic ovary syndrome, endometriosis and gynaecological cancers, highlighting the translational potential of incretin‐based therapies for metabolic‐associated gynaecological disorders. ABSTRACT Background Obesity is a major global public health concern closely linked to the development and ...
Jiayu Yan +10 more
wiley +1 more source
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho +8 more
wiley +1 more source

