Results 71 to 80 of about 6,714 (159)

The "ram effect": new insights into neural modulation of the gonadotropic axis by male odors and socio-sexual interactions [PDF]

, 2015
Reproduction in mammals is controlled by the hypothalamo-pituitary-gonadal (HPG) axis under the influence of external and internal factors such as photoperiod, stress, nutrition, and social interactions.
Abbott, Alim, Bakker, Baldwin, Baum, Beltramino, Ben Saïd, Birch, Blache, Boehm, Brennan, Brennan, Buck, Budry, Cahill, Caraty, Caraty, Chand, Chanvallon, Chanvallon, Chanvallon, Chanvallon, Chemineau, Clarke, Clarkson, Claude Fabre-Nys, Cohen-Tannoudji, Cohen-Tannoudji, Cohen-Tannoudji, De Bond, Dobson, Dorries, Dyrmundsson, Eley, Fabre-Nys, Fabre-Nys, Fabre-Nys, Fabre-Nys, Fabre-Nys, Fabre-Nys, Ferin, Fisher, Follett, Franceschini, Fulkerson, Gelez, Gelez, Gelez, Gelez, Ghenim, Gitler, Goldman, Goodman, Goodman, Goodman, Goodman, Goodman, Goodman, Goodman, Hamada, Hauger, Hawken, Hawken, Hawken, Herbison, Herbison, Herbison, Hodson, Hoffman, Hudson, Ichimaru, Jansen, Jiang, Johnson, Jorre de St. Jorre, Karsch, Karsch, Karsch, Kaynard, Keith M. Kendrick, Kelliher, Kendrick, Kevetter, Knight, Knight, Knobil, Kumar, Land, Lee, Lehman, Lindsay, Lindsay, Lévy, Maeda, Malpaux, Martin, Martin, Mauléon, Merkley, Messager, Mikkelsen, Moenter, Mori, Mormede, Murata, Murphy, Murtagh, Ohara, Ohkura, Oldham, Oldham, Oldham, Over, Pearce, Perkins, Pinilla, Poindron, Rex J. Scaramuzzi, Rivier, Roa, Sanchez-Andrade, Sara, Scaramuzzi, Shea, Shipka, Signoret, Signoret, Skinner, Swaney, Swann, Szawka, Thimonier, Tillet, Tillet, Tomaszewska-Zaremba, Tong, Tournadre, Treves, Tsutsumi, Uenoyama, Underwood, Ungerfeld, Ungerfeld, Vandenbergh, Walkden-Brown, Watson, Wersinger, Whitten, Yang, Yang, Yang, Yoon   +151 more
core   +4 more sources

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

Advanced Biology, Volume 10, Issue 1, January 2026.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau, Monica A. Rionda, Evelyn Cho, Jamison G. Clark, Robin E. Kruger, Ruth K. Chan‐Sui, Vasantha Padmanabhan, Molly B. Moravek, Ariella Shikanov   +8 more
wiley   +1 more source

Functional examination of novel kisspeptin phosphinic peptides [PDF]

, 2018
Kisspeptins acting on their cognate G protein-coupled receptor, kisspeptin receptor, play important roles in the suppression of cancer cell metastasis and regulation of the reproductive system, and therefore are important for therapeutic intervention ...
Fernig, David, Lu, Zhi-Liang, Matziari, Magdalini, Meng, Jia, Rong, Rong, Xie, Yixin, Zhang, Xiaoyang   +6 more
core   +4 more sources

Concentration–QTc Modeling to Support Clinical Development of Fezolinetant

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin‐3 receptor antagonist that blocks neurokinin B activation of kisspeptin/neurokinin B/dynorphin neurons to thereby modulate neuronal activity in the thermoregulatory center. Fezolinetant has been approved in many regions, including North America, Europe, Asia, and Australia for the treatment ...
Jace C. Nielsen, Masako Saito, Xuegong Wang, Megumi Iwai, Graeme L. Fraser, Steven Ramael, Jiayin Huang   +6 more
wiley   +1 more source

The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons. [PDF]

, 2013
Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide.
Chilumuri, A., Chilumuri, A., Milton, N.G.N., Milton, N.G.N.   +3 more
core   +6 more sources

Glutamatergic and GABAergic Innervation of Human Gonadotropin-Releasing Hormone-I Neurons [PDF]

, 2012
Amino acid (aa) neurotransmitters in synaptic afferents to hypothalamic GnRH-I neurons are critically involved in the neuroendocrine control of reproduction. Although in rodents the major aa neurotransmitter in these afferents is gamma-aminobutyric acid (
Barbara Vida, Beáta Á. Borsay, Csilla S. Molnár, Erik Hrabovszky, Imre Kalló, Kálmán Rácz, László Herczeg, Masahiko Watanabe, Róbert Nagy, Zsolt Liposits   +9 more
core   +1 more source

Insulin: Its role in the central control of reproduction [PDF]

Insulin has long been recognized as a key regulator of energy homeostasis via its actions at the level of the brain, but in addition, plays a role in regulating neural control of reproduction.
Abi Salloum, Adashi, Aerts, Ahmed, Alexander, Backholer, Bakker, Banks, Banks, Banks, Banks, Banting, Baskin, Bates, Baura, Bell, Benoit, Benyshek, Bergendahl, Bestetti, Billington, Boddi, Bogda Skowronska, Brüning, Bucholtz, Butler, Bygren, Caraty, Castellano, Castellano, Castellano, Cernea, Chavarro, Cheng, Chowers, Chrysanthi Fergani, Clarke, Clarke, Clegg, Costa, Crown, de Roux, DiVall, Dobson, Donato, Dong, Dorn, Dorn, Dyer, Evans, Fergani, Fergani, Fergani, Fergani, Fernandez-Fernandez, Fernandez-Twinn, Fowden, Franks, Frisch, Gamba, Ghasemi, Godfrey, Gomez, Goodman, Goodman, Hales, Hammoud, Havrankova, Havrankova, Hileman, Hill, Hill, Ibanez, Ibanez, Ibanez, Jansen, Jennes, Jeong-Hyung Lee, Jezova, Jimenez-Chillaron, Joanna H. Sliwowska, Kaati, Kaati, Karsch, Katayama, Kawaguchi, Kienast, Kim, King, Kiyma, Konner, Kosior-Korzecka, Kovacs, Lakkakula, Law, Lawson, Lehman, Lehman, Lehman, Leranth, Levin, Lim, Liu, Lujan, Lungu, Luque, Mackey, Maheshwari, Margolis, Matthews, McClure, McMillen, Meaney, Medina, Medina, Michael N. Lehman, Miller, Milner, Monika Gawałek, Morton, Myers, Navarro, Navarro, Nef, Ng, Norgren, Ollmann, Pagan, Pasquali, Pembrey, Phillips, Phillips, Pinheiro, Piotr Fichna, Pitetti, Plagemann, Plagemann, Plant, Plum, Qi, Qin, Qiu, Qiu, Ravelli, Rittenberg, Roa, Roa, Roseboom, Rosenfield, Saifullizam, Sato, Schechter, Schneider, Schoeller, Seminara, Seminara, Semple, Sharma Tejinder, Sheppard, Silverman, Silverman, Smith, Stein, Sullivan, Tang, Taylor, Taylor, Thamotharan, Tosi, True, Valdes, van der Steeg, Veiga-Lopez, Wahab, Wang, Watanobe, Welberg, Williams, Witchel, Woods, Woods, Xita, Xu, Young   +183 more
core   +1 more source

Presence of two alternative splice isoforms of the kisspeptin-1 receptor (kiss1r) in a modern teleost, the Senegalese sole (Solea senegalensis)

, 2008
1st World Conference on Kisspeptin Signaling in the Brain, 8-11 October 2008 ...
Mechaly, Alejandro S., Viñas, Jordi, Piferrer, Francesc   +2 more
openaire   +1 more source

Oestrogen Induces Rhythmic Expression of the Kisspeptin-1 Receptor GPR54 in Hypothalamic Gonadotrophin-Releasing Hormone-Secreting GT1-7 Cells [PDF]

Journal of Neuroendocrinology, 2011
K. J. Tonsfeldt, C. P. Goodall, K. L. Latham, P. E. Chappell   +3 more
openaire   +1 more source

Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. [PDF]

, 2019
BackgroundThe mechanisms whereby neuroinflammation negatively affects neuronal function in the hypothalamus are not clear. Our previous study determined that obesity-mediated chronic inflammation elicits sex-specific impairment in reproductive function ...
Coss, Djurdjica, Lainez, Nancy M
core   +1 more source