Results 1 to 10 of about 16,204 (223)

Relationship between kisspeptin-10, neurokinin B and dynorphin A in the course of normal and delayed puberty in ewes [PDF]

Journal of Veterinary Research
Kisspeptin (KiSS), neurokinin B (NKB) and dynorphin A (Dyn A) participate in the neuroendocrine regulation of reproductive system development and functioning; however, their roles in the onset of sexual maturity and pathomechanism of delayed puberty have
Szysiak Natalia, Kosior-Korzecka Urszula, Greguła-Kania Monika, Patkowski Krzysztof, Fila Mateusz, Junkuszew Andrzej   +5 more
doaj   +2 more sources

Homeostatic scaling of dynorphin signaling by a non-canonical opioid receptor [PDF]

Nature Communications
The endogenous opioid system provides powerful control over emotions, nociception, and motivation among many other fundamental nervous system functions.
Xiaona Li, Nathan D. Winters, Shubhi Pandey, Colten Lankford, Hannah M. Stoveken, Emery Smith, Chu-Ting Chang, Stefano Zucca, Louis Scampavia, Timothy Spicer, Kirill A. Martemyanov   +10 more
doaj   +2 more sources

Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor [PDF]

Journal of Neuroinflammation, 2018
Background We previously reported that ginsenoside Re (GRe) attenuated against methamphetamine (MA)-induced neurotoxicity via anti-inflammatory and antioxidant potentials.
Duy-Khanh Dang, Eun-Joo Shin, Dae-Joong Kim, Hai-Quyen Tran, Ji Hoon Jeong, Choon-Gon Jang, Seung-Yeol Nah, Jung Hwan Jeong, Jae Kyung Byun, Sung Kwon Ko, Guoying Bing, Jau-Shyong Hong, Hyoung-Chun Kim   +12 more
doaj   +4 more sources

Effect of neurokinin B and dynorphin A on kisspeptin-10 secretion from the anterior pituitary cells of pubescent ewes in vitro [PDF]

Journal of Veterinary Research
Neurokinin B (NKB), dynorphin A (Dyn A) and kisspeptin (KiSS) are key agents that participate in the neuroendocrine regulation of the development and functioning of the reproductive system.
Szysiak Natalia, Kosior-Korzecka Urszula, Greguła-Kania Monika, Patkowski Krzysztof, Fila Mateusz, Junkuszew Andrzej   +5 more
doaj   +2 more sources

Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects [PDF]

Journal of Pain Research
Seung-Ho Choi,* Yu-Mi Kim,* Jo-Young Son, Dong-Kuk Ahn Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Korea*These authors contributed equally to this workCorrespondence: Dong-Kuk Ahn, Department of ...
Choi SH, Kim YM, Son JY, Ahn DK
doaj   +2 more sources

Enhanced dynorphin expression and secretion in pancreatic beta-cells under hyperglycemic conditions [PDF]

Molecular Metabolism
Objective: Dynorphin, an endogenous opioid peptide predominantly expressed in the central nervous system and involved in stress response, pain, and addiction, has intrigued researchers due to its expression in pancreatic β-cells.
Miranda Movahed, Ruy A. Louzada, Manuel Blandino-Rosano   +2 more
doaj   +2 more sources

Influence of neurokinin B, dynorphin A and kisspeptin-10 on in vitro gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes [PDF]

Journal of Veterinary Research
The hypothalamic neuropeptides kisspeptin-10 (KiSS-10), neurokinin B (NKB), and dynorphin A (Dyn A) play roles in the endocrine regulation of the hypothalamic–pituitary–ovarian (HPO) axis in puberty.
Szysiak Natalia, Kosior-Korzecka Urszula, Longo Vincenzo, Patkowski Krzysztof, Greguła-Kania Monika, Nowakiewicz Aneta, Bochniarz Mariola, Junkuszew Andrzej   +7 more
doaj   +2 more sources

Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides

eLife, 2021
Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstream ...
Jennifer M Kunselman, Achla Gupta, Ivone Gomes, Lakshmi A Devi, Manojkumar A Puthenveedu   +4 more
doaj   +1 more source

Kisspeptin, Neurokinin B, and Dynorphin Expression during Pubertal Development in Female Sheep

Biology, 2021
The neural mechanisms underlying increases in gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion that drive puberty onset are unknown.
Eliana G. Aerts, KaLynn Harlow, Max J. Griesgraber, Elizabeth C. Bowdridge, Steven L. Hardy, Casey C Nestor, Stanley M. Hileman   +6 more
doaj   +1 more source

Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus [PDF]

PeerJ, 2016
Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in the arcuate nucleus (ARC) play a key role in gonadotropin-releasing hormone (GnRH) pulse generation and gonadal steroid feedback, with kisspeptin driving GnRH ...
Valeria M. Tanco, Brian K. Whitlock, Melaney A. Jones, Robyn R. Wilborn, Terry D. Brandebourg, Chad D. Foradori   +5 more
doaj   +2 more sources