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Opioid and Nonopioid Cardiovascular Effects of Dynorphins
1996Publisher Summary The endogenous opioid peptides peptides are derived from three separate protein precursors, which upon proteolytic cleavage generate distinct classes of opioid compounds. One of these precursors is prodynorphin, which generates Dyn A, Dyn B, α- and β-neo-End, and leumorphin.
Michel Dumont, Simon Lemaire
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Dynorphin immunoreactivity in the toad neurointermediate lobe
Life Sciences, 1982Abstract The predominant immunoreactive dynorphin in the toad neurointermediate lobe was similar to that isolated from toad brain with respect to its apparent molecular weight and HPLC retention time. Specific immunoreactive dynorphin staining was present within pars nervosa but not within pars intermedia or pars distalis based on immunohistochemical
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Dynorphin antibodies bind microbial protein sequences that mimic dynorphin
Biological Psychiatry, 1994Chawki Benkelfat +3 more
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Spinal Dynorphin and Neuropathic Pain
2009The endogenous neuropeptides dynorphins are proteolytic products of prodynorphin which are characterized by their high affinity for opioid receptors. Dynorphin A is widely distributed in the CNS and in the spinal cord is found predominantly in neurons of laminae I/II and V.
Josephine Lai +2 more
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Dynorphin A activates bradykinin receptors to maintain neuropathic pain
Nature Neuroscience, 2006J. Lai +6 more
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