Results 171 to 180 of about 9,925 (218)

Myocardial phosphoproteomics unveils a key role of DYRK1A in aortic valve replacement-induced reverse remodelling. [PDF]

Basic Res Cardiol
Trindade F, Almeida-Coelho J, Sousa-Mendes C, Saraiva F, Arbonés ML, Leite-Moreira A, Vitorino R, Falcão-Pires I.   +7 more
europepmc   +1 more source

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A. [PDF]

Nat Genet
Brierley CK, Yip BH, Orlando G, Wen J, Wen S, Goyal H, Levine M, Jakobsdottir GM, Tapinos A, Cornish AJ, Rodriguez-Romera A, Rodriguez-Meira A, Bashton M, Hamblin A, Clark SA, Hamley JC, Fox O, Giurgiu M, O'Sullivan J, Murphy L, Adamo A, Olijnik AA, Cotton A, Hendrix E, Narina S, Pruett-Miller SM, Enshaei A, Harrison C, Drummond M, Knapper S, Tefferi A, Antony-Debré I, Davies J, Henssen AG, Thongjuea S, Wedge DC, Constantinescu SN, Papaemmanuil E, Psaila B, Crispino JD, Mead AJ.   +40 more
europepmc   +1 more source

Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration. [PDF]

Bone Res
Cheng Z, Gao H, Shi P, Zhang A, Chen X, Chen Y, Gan W, Zhao K, Li S, Yang C, Zhang Y.   +10 more
europepmc   +1 more source

Drug-induced regeneration of pancreatic beta cells: An approach to cellular therapeutic targets. [PDF]

Cell Regen
Parsi P, Saharkhiz S, Farani MR, Bakhtiyari S, Alipourfard I.   +4 more
europepmc   +1 more source

<i>DYRK1A</i> syndrome presenting with a familial exudative vitreoretinopathy (FEVR)-like retinovascular phenotype. [PDF]

Ophthalmic Genet
Lin S, Hay E, Thompson DA, Moosajee M, Webster AR, Mahroo OA, Henderson RH, Arno G.   +7 more
europepmc   +1 more source

A novel dual DYRK1A/B inhibitor for the treatment of type 1 diabetes. [PDF]

Front Pharmacol
Tumas Š, Mingaila J, Baranauskas V, Baltrukonytė E, Orla L, Krasko JA, Pocevičiūtė R, Berlina D, Belenky A, Vilenchik M, Vaitkevičienė A, Potapova O, Burokas A.   +12 more
europepmc   +1 more source

DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition. [PDF]

Leukemia
Ayyadevara VSSA, Wertheim G, Gaur S, Chukinas JA, Loftus JP, Lee SJ, Kumar A, Swaminathan S, Bhansali RS, Childers W, Geng H, Milne TA, Hua X, Bernt KM, Besson T, Shi J, Crispino JD, Carroll M, Tasian SK, Hurtz C.   +19 more
europepmc   +1 more source

Tricyclic Isatin Derivatives as Anti-Inflammatory Compounds with High Kinase Binding Affinity. [PDF]

Molecules
Uvarov AV, Schepetkin IA, Quinn MT, Khlebnikov AI.   +3 more
europepmc   +1 more source