Types of Pain in Multiple System Atrophy
Movement Disorders, EarlyView.Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese +19 more
wiley +1 more source
Autonomic Dysfunction after Mild Traumatic Brain Injury
Brain Sciences, 2017 A mild traumatic brain injury (mTBI) is a complex pathophysiologic process that has a systemic effect on the body aside from solely an impairment in cognitive function.
Dmitry Esterov, Brian D. Greenwald
doaj +1 more source
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]
, 2015 BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony +12 more
core +2 more sources
Early Autonomic Burden in Prodromal Parkinson's Disease Predicts Cognitive Impairment
Movement Disorders, EarlyView.Abstract Background Autonomic dysfunction is a known contributor to cognitive impairment in Parkinson's disease (PD), but its impact during prodromal stage is unknown. Objective The aim was to determine whether early autonomic burden predicts incident cognitive impairment in prodromal PD.
A. Enrique Martinez‐Nunez +5 more
wiley +1 more source
, 1994 En el presente trabajo, se efectúa una revisión completa del síndrome disautonomía felina, así como la descripción de un caso clínico correspondiente a un gato macho de 11 meses de edad, junto con los medios de diagnóstico utilizado.At the present ...
Bayón del Río, Alejandro Ángel +5 more
core
When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions
Movement Disorders, EarlyView.Abstract Although Parkinson's disease (PD) is classically defined by its motor features, non‐motor symptoms exert a substantial and often under‐recognized influence on disease trajectory. Among these, weight loss has long been observed in PD and other neurodegenerative disorders, yet the mechanisms remain incompletely understood.
Ellie D. Gabriel +6 more
wiley +1 more source
The Micro-Structure of the Celiac Ganglia—A Two-Photon Microscopy Study on Parkinson’s Disease
DiagnosticsBackground/Objectives: This study explores the micro-structure of celiac ganglia using two-photon microscopy (TPM) to highlight histological features in neurodegenerative conditions.
Diana-Theodora Morgos +9 more
doaj +1 more source
Advancing Precision Medicine through clinical grade whole genome sequencing, return of results and deep brain stimulation [PDF]
, 2013 CSHL Meetings and Course: Precision Medicine: Personal Genomes & Pharmacogenomics, November 13th - November 16th ...
Lyon, Gholson J.
core
A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex [PDF]
, 2014 Elongator is a conserved, multi-protein complex discovered in Saccharomyces cerevisiae, loss of which confers a range of pleiotropic phenotypes. Elongator in higher eukaryotes is required for normal growth and development and a mutation in the largest ...
Amberg D.C. +5 more
core +4 more sources
Effect of Surgical Fusion on Volitional Weight-Shifting in Individuals With Adolescent Idiopathic Scoliosis [PDF]
, 2016 Study Design Prospective. Objectives The goals of this study were to (1) evaluate the differences in weightbearing symmetry between individuals with adolescent idiopathic scoliosis (AIS) and typically developing controls; (2) observe the effect of ...
Kurapati, Nikhil T. +8 more
core +3 more sources