Results 61 to 70 of about 16,532 (175)

Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Dysautonomia in Adolescent Athletes with Persistent Post‑Concussion Complaints

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers' Association
OBJECTIVE/BACKGROUND Dysautonomia is dysfunction in autonomic nervous system manifesting following concussion, contributing to Persistent Post‑Concussion Complaints (PPCC). Patients with dysautonomia may present with dizziness, tachycardia, postural
Jason Cruickshank
doaj   +1 more source

Elevated Nocturnal CO2 and Autonomic Dysfunction in Children With Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Sleep‐disordered breathing (SDB) frequently complicates Down syndrome (DS). Beyond upper airway obstruction, emerging evidence suggests an autonomic nervous system (ANS) dysfunction affecting CO2 regulation. The aim of this study was to investigate nocturnal gas exchanges in children with DS and compare them to what has been ...
Jessica Taytard, Segolène Falquero, Sophie Denamur, Pierre‐Yves Boelle, Karl Leroux, Harriet Corvol, Aimé Ravel, Clotilde Mircher, Jeanne Toulas, Emmanuelle Prioux, Marie‐Anne Caillaud, Guillaume Aubertin, Hervé Walti   +12 more
wiley   +1 more source

Dysautonomia as the Presenting Symptom in Anti-Muscle-Specific Kinase Antibody Myasthenia Gravis

, 2020
In an minority of Myasthenia Gravis (MG) patients, the autoantibodies bind to muscle-specific kinase (MUSK). These MuSK antibody-mediated MG (MuSK MG) patients are not only immunologically distinct, but also have different characteristic clinical ...
L. Dawson, Gilhuis, H.J., Niks, E.H., T.J.S. Bekooij, E.H. Niks, Dawson, L., H.J. Gilhuis, Bekooij, T.J.S.   +7 more
core   +1 more source

Ganglion cytology: a novel rapid method for the diagnosis of equine dysautonomia [PDF]

, 2018
Equine dysautonomia (grass sickness) is characterized by autonomic neuronal degeneration and is often fatal. As outbreaks occur, rapid diagnosis is essential but confirmation currently requires histological examination.
Piccinelli, Chiara, Milne, Elspeth, Jago, Rachel   +2 more
core   +1 more source

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder, Suzanna E. L. Temple, Niall Jefferson, David Brown, Kasee Stratton‐Gadke, Madelene Rich, Steve Rose, Kim Blake   +7 more
wiley   +1 more source

The Seattle Trauma and Autonomic Related Sleep Symptoms (STARSS) Scale: A Novel Self‐Report Measure of Sleep Disturbances With Nightmares and Autonomic Symptoms Following Trauma

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep disruption is a common hallmark of posttraumatic stress disorder (PTSD), causing significant distress and often persisting after remission of other symptoms. Autonomic dysregulation is commonly comorbid and has been implicated in the underlying pathophysiology of both wake‐ and sleep‐related symptoms following trauma.
Garth E. Terry, Aaron F. Rosser, Katharine J. Liang, Kim L. Hart, Sarah B. Campbell, Murray A. Raskind, Rebecca C. Hendrickson   +6 more
wiley   +1 more source

α-Catulin maps to the familial dysautonomia region on 9q31

, 2001
Familial dysautonomia is a severe autosomal-recessive neurodegenerative disease that primarily affects the Ashkenazi Jewish population. We present the mapping of α-catulin and show that it maps precisely to the familial dysautonomia candidate region on ...
Paula C Demacio, Peter N Ray
core   +1 more source

Reflex Syncope With Complete Heart Block Triggered by Swallowing in a Patient on Immune Checkpoint Inhibitor Therapy

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon, Michael Oropesa, Bardia Adibmoradi, Daniel Weitz   +3 more
wiley   +1 more source