Results 111 to 120 of about 132,138 (294)

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

open access: yesAdvanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu   +8 more
wiley   +1 more source

Bacterial dysbiosis risk prediction according to vaginal normobiota indicator [PDF]

open access: yes, 2020
Vaginal bacterial dysbiosis is evident by the progressive growth of obligate and optional anaerobic bacteria, myco- and ureaplasmas and fungi against the background of a sharp decrease in the number of lactobacilli.
Hruzevskyi, O.
core  

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

MICROFLORA OF THE ORAL CAVITY CHANGE DEPENDING UPON THE DURATION OF REMOVABLE DENTURES USE

open access: yesУкраїнський стоматологічний альманах, 2018
Pathological changes in the mouth that lead to the development of dental diseases occur in violation of the normal microflora of the mouth, which provides anticolonization resistance, prevents colonization of the body from other microorganisms.
T. Y. Divnych
doaj  

A theoretical model of temperate phages as mediators of gut microbiome dysbiosis [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Bacteriophages are the most prominent members of the gut microbiome, outnumbering their bacterial hosts by a factor of 10. Phages are bacteria-specific viruses that are gaining attention as highly influential regulators of the gut bacterial community ...
Derek M. Lin, Henry C. Lin
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

open access: yesAdvanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang   +17 more
wiley   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

open access: yesAdvanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou   +10 more
wiley   +1 more source

Stress triggers gut dysbiosis via CRH-CRHR1-mitochondria pathway

open access: yesnpj Biofilms and Microbiomes
Stress can lead to gut dysbiosis in brain-gut axis disordered diseases as irritable bowel syndrome (IBS), yet the mechanisms how stress transfer from the brain to the gut and disrupt gut microbiota remain elusive.
Yiming Zhang   +10 more
doaj   +1 more source

Opioid-induced microbial dysbiosis

open access: yes, 2023
The aim of this bachelor thesis is to describe the consequences of opioids in relation to the gut microbiome. Chronic opioid use induces microbial dysbiosis in the gut, where both functional and structural changes in the composition of the microbiome ...
Popjak, Šimon
core  

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