Results 91 to 100 of about 199,474 (298)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 The incidence of nonalcoholic fatty liver disease (NAFLD) is increasing recently and has become one of the most common clinical liver diseases. Since the pathogenesis of NAFLD has not been completely elucidated, few effective therapeutic drugs are ...
Jie Fang +6 more
semanticscholar +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Mucosaprotective action of the phytopreparation "Biotrit" at experimental hepatogenic colitis
Journal of Education, Health and Sport, 2017 Aim: To determine the role of dysbiosis in the development of colitis and to show the therapeutic and preventive effects of the phytopreparation "Biotrit" at this pathology.
A. V. Bocharov
doaj +3 more sources
Pathogenesis and therapeutic opportunities of gut microbiome dysbiosis in critical illness
Gut microbesFor many years, it has been hypothesized that pathological changes to the gut microbiome in critical illness is a driver of infections, organ dysfunction, and other adverse outcomes in the intensive care unit (ICU).
Nicole A Cho +3 more
semanticscholar +1 more source
Microbial dysbiosis in the gut drives systemic autoimmune diseases
Frontiers in Immunology, 2022 Trillions of microbes survive and thrive inside the human body. These tiny creatures are crucial to the development and maturation of our immune system and to maintain gut immune homeostasis.
W. Mousa, F. Chehadeh, Shannon Husband
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Education, Health and Sport, 2020 A model for predicting the severity of dysbiosis according to the index of opportunistic pathogenic microflora has been developed. The aim of the study is to identify the most informative indicators that objectively reflect the condition of the ...
O. A. Hruzevskyi +2 more
doaj +1 more source
The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders
Cells, 2022 Mounting evidence shows that the complex gut microbial ecosystem in the human gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via microbiota and the gut–brain (MGB) axis.
N. Anand, V. Gorantla, S. Chidambaram
semanticscholar +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source