Results 131 to 140 of about 140,996 (352)
Dietary Contamination With Neonicotinoid (Clothianidin) Gradient Triggers Specific Dysbiosis Signatures of Microbiota Activity Along the Honeybee (Apis Mellifera) Digestive Tract [PDF]
, 2020 Sarah El Khoury +5 more
openalex +1 more source
Advanced Science, EarlyView.IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang +11 more
wiley +1 more source
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Nature, 2012 Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and the leading cause of chronic liver disease in the Western world.
Jorge Henao-Mejia +14 more
semanticscholar +1 more source
Advanced Science, EarlyView.Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang +5 more
wiley +1 more source
Defining Dysbiosis for a Cluster of Chronic Diseases
Scientific Reports, 2019 The prevalence of many chronic diseases has increased over the last decades. It has been postulated that dysbiosis driven by environmental factors such as antibiotic use is shifting the microbiome in ways that increase inflammation and the onset of ...
Egon Willighagen
semanticscholar +1 more source
Dysbiosis From a Microbial and Host Perspective Relative to Oral Health and Disease [PDF]
, 2021 Carla Cugini +3 more
openalex +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Stress triggers gut dysbiosis via CRH-CRHR1-mitochondria pathway
npj Biofilms and MicrobiomesStress can lead to gut dysbiosis in brain-gut axis disordered diseases as irritable bowel syndrome (IBS), yet the mechanisms how stress transfer from the brain to the gut and disrupt gut microbiota remain elusive.
Yiming Zhang +10 more
doaj +1 more source
The Korean Journal of Obesity, 2015 Recent studies have described an association between obesity and gut microbiota, suggesting that the latter might play a critical role in the development of the former. Possible mechanisms by which gut microbiota can mediate obesity are by changes in gut microbiota which can influence energy absorption, modulate associated enzymes and induce low-grade ...
openaire +2 more sources