Results 191 to 200 of about 132,138 (294)

The role of the gut mycobiota in neurodevelopmental disorders: a multikingdom disruption of the gut-brain axis. [PDF]

Front Microbiol
Hu Y, Yu XL, Zhang XJ, Ma LT.
europepmc   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Unraveling the intricate link: gut microbiota and recurrent spontaneous abortion. [PDF]

Front Reprod Health
Li D, Liu X, Teng Z, Yang C, Chen X, Tan P.   +5 more
europepmc   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

The microbiome-inflammation-immune axis in oral squamous cell carcinoma: from mechanistic insights to therapeutic perspectives. [PDF]

Front Immunol
Wang Z, Bian Q, Chu Y, Zhu W, Qin Y, Zheng J.   +5 more
europepmc   +1 more source

CD8+ T Cell-Derived Perforin Exacerbates Dysbiosis and Inflammatory Bowel Disease via β-Hydroxybutyrate Suppression in Mouse Colonic Epithelium

Shiyang Huang,1,2,* Lehan Pan,3– 5,* Mingyang Li,1,2 Shu Pang,4– 7 Yue Tian,8 Wen Shi,1,2 Ye Zong,4– 6 Dong Zhang,8– 10 Dan Tian3– 5 1Immunology Research Center for Oral and Systemic Health, Beijing Clinical Research Institute, Beijing ...
Huang S, Pang S, Zhang D, Zong Y, Tian Y, Shi W, Tian D, Pan L, Li M   +8 more
core  

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Gut Microbial Dysbiosis and Male Reproductive Health: Current Insights and Future Directions. [PDF]

Int J Mol Sci
Pan M, O'Flaherty C.
europepmc   +1 more source

Tracking Dysbiosis Where It Matters [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2020
openaire   +3 more sources