Results 61 to 70 of about 1,185,879 (186)

Expression-based decision tree model reveals distinct microRNA expression pattern in pediatric neuronal and mixed neuronal-glial tumors

BMC Cancer, 2019
Background The understanding of the molecular biology of pediatric neuronal and mixed neuronal-glial brain tumors is still insufficient due to low frequency and heterogeneity of those lesions which comprise several subtypes presenting neuronal and/or ...
Magdalena Zakrzewska, Renata Gruszka, Konrad Stawiski, Wojciech Fendler, Joanna Kordacka, Wiesława Grajkowska, Paweł Daszkiewicz, Paweł P. Liberski, Krzysztof Zakrzewski   +8 more
doaj   +1 more source

A Nationwide Central Diagnosis for Pediatric CNS Tumors in Japan: The JCCG Brain Tumor and Pathology Committees

Cancer Science, Volume 117, Issue 7, Page 1975-1984, July 2026.
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano, Junko Hirato, Takako Yoshioka, Tetsuya Takimoto, Sumihito Nobusawa, Kaishi Satomi, Ran Tomomasa, Seiji Yamada, Taku Homma, Shoh Sasaki, Ayako Yamazaki, Maki Sakaguchi, Yasuhide Takeuchi, Nei Fukazawa, Kai Yamasaki, Kohei Fukuoka, Yui Shinohara Kimura, Yuki Nagayama, Yohei Inoue, Akira Miyahira, Ema Yoshioka, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Yuko Hibiya, Yuko Matsushita, Mai Honda Kitahara, Yuki Yomoda, Miho Kato, Michael D. Taylor, Yasuhito Arai, Tatsuhiro Shibata, Hiroaki Sakamoto, Keita Terashima, Yoshiki Arakawa, Toshihiro Kumabe, Ryo Nishikawa, Junichi Hara, Yonehiro Kanemura, Koichi Ichimura   +39 more
wiley   +1 more source

Intraventricular dysembryoplastic neuroepithelial tumour: case report

, 2012
Dysembryoplastic neuroepithelial tumour (DNT) is located in the cerebral cortex with very few exceptions. In this article, an extremely rare case of intraventricular DNT originating from the septum pellucidum is ...
Pasaoglu, Aydin, Kaymaz, Memduh, Emmez, Hakan, KALE, AYDEMİR, Eser, Pinar, Egemen, Emrah   +5 more
core   +1 more source

Functional Segregation of Epileptogenicity within the Human Amygdala

Annals of Neurology, Volume 99, Issue 6, Page 1598-1612, June 2026.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys, Julia Makhalova, Samuel Medina Villalon, Maria Fratello, Hugo Dary, Stanislas Lagarde, Francesca Pizzo, Agnès Trébuchon, Maxime Guye, Jean‐Philippe Ranjeva, Romain Carron, Didier Scavarda, Christian‐George Bénar, Bernard Giusiano, Fabrice Bartolomei   +14 more
wiley   +1 more source

Coupling between infraslow activities and high‐frequency oscillations precedes seizure onset

Epilepsia Open, 2020
Infraslow activities and high‐frequency oscillations (HFOs) are observed in seizure‐onset zones. However, the relation between them remains unclear. In this study, we investigated phase‐amplitude coupling between infraslow phase (0.016‐1 Hz) and HFOs ...
Hiroaki Hashimoto, Hui Ming Khoo, Takufumi Yanagisawa, Naoki Tani, Satoru Oshino, Haruhiko Kishima, Masayuki Hirata   +6 more
doaj   +1 more source

The usefulness of intraoperative electrocorticography (iECoG) in pediatric temporal lobe epilepsy surgery

Epileptic Disorders, Volume 28, Issue 2, Page 401-408, April 2026.
Abstract Objective This study aimed to evaluate the usefulness of intraoperative electrocorticography (iECoG) in providing a more accurate surgical strategy, thereby yielding seizure freedom following resective surgery in children with temporal lobe epilepsy (TLE).
Rafael Andrade Cruz, João Paulo Sant’ Ana Santos de Souza, Davi Casale Aragon, Úrsula Thomé Costa, Ana Paula Andrade Hamad, Américo Ceiki Sakamoto, Antônio Carlos dos Santos, Hélio Rubens Machado, Marcelo Volpon Santos   +8 more
wiley   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, Volume 36, Issue 2, March 2026.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor

Acta Neuropathologica Communications, 2020
The FGFR1 gene encoding fibroblast growth factor receptor 1 has emerged as a frequently altered oncogene in the pathogenesis of multiple low-grade neuroepithelial tumor (LGNET) subtypes including pilocytic astrocytoma, dysembryoplastic neuroepithelial ...
Calixto-Hope G. Lucas, Rohit Gupta, Pamela Doo, Julieann C. Lee, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette K. Kleinschmidt-DeMasters, Han S. Lee, Matthew D. Wood, Marjorie Grafe, Donald Born, Hannes Vogel, Shahriar Salamat, Diane Puccetti, David Scharnhorst, David Samuel, Tabitha Cooney, Elaine Cham, Lee-way Jin, Ziad Khatib, Ossama Maher, Gabriel Chamyan, Carole Brathwaite, Serguei Bannykh, Sabine Mueller, Cassie N. Kline, Anu Banerjee, Alyssa Reddy, Jennie W. Taylor, Jennifer L. Clarke, Nancy Ann Oberheim Bush, Nicholas Butowski, Nalin Gupta, Kurtis I. Auguste, Peter P. Sun, Jarod L. Roland, Corey Raffel, Manish K. Aghi, Philip Theodosopoulos, Edward Chang, Shawn Hervey-Jumper, Joanna J. Phillips, Melike Pekmezci, Andrew W. Bollen, Tarik Tihan, Susan Chang, Mitchel S. Berger, Arie Perry, David A. Solomon   +50 more
doaj   +1 more source

The epileptologist's perspective of focal cortical dysplasia type 3: From concept to management

Epilepsia, Volume 67, Issue 3, Page 1017-1031, March 2026.
Abstract The recent International League Against Epilepsy (ILAE) official and updated classification of focal cortical dysplasia (FCD) includes a third type—FCD type 3—characterized by architectural abnormalities (cortical dyslamination) associated with another “principal” lesion: hippocampal sclerosis (HS), developmental tumors, vascular malformations,
André Palmini, Francine Oliveira, Eliseu Paglioli, Harvey Sarnat, Ricardo Paganin, Ricardo Soder, William Martins, Rafael Paglioli, Thomas Frigeri, Fernanda Schuh, Vicenzo Zarpellon   +10 more
wiley   +1 more source

Alpha‐B‐crystallin immunohistochemistry: A sensitive but non‐specific marker for epileptogenic lesions

Brain Pathology, Volume 36, Issue 5, September 2026.
Ekin Güney, Ilay Caliskan, Tara Saunders, Mercedes Paredes, Calixto‐Hope Lucas, Kanish Mirchia, Rufei Lu, Merryl Terry, Erika Cagampan, Melike Pekmezci, Andrew Bollen, Arie Perry, Cathryn R. Cadwell, Tarık Tihan   +13 more
wiley   +1 more source