Results 1 to 10 of about 27,542 (202)

Case Report: Unclassifiable cerebellar high-grade neuroepithelial tumor with a CCDC6::RET fusion manifesting explosive recurrence [PDF]

Frontiers in Surgery
A 20-year-old woman presented with a 1-month history of positional vertigo, occipital headaches, and progressive gait ataxia. Neuroimaging demonstrated a 3.7 × 4.2 × 3.3 cm heterogeneously enhancing mass in the left cerebellar hemisphere with fourth ...
Moksada Regmi, Moksada Regmi, Moksada Regmi, Moksada Regmi, Shikun Liu, Shikun Liu, Shikun Liu, Ying Xiong, Ying Xiong, Ying Xiong, Junyi Liu, Junyi Liu, Junyi Liu, Zihan Zhao, Xu Zhang, Xu Zhang, Chenlong Yang, Chenlong Yang, Chenlong Yang, Sino-Uzbek Regenerative Therapy Consortium (SURE)   +19 more
doaj   +2 more sources

H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components [PDF]

Acta Neuropathologica Communications, 2019
The recently described malignant neuro-epithelial tumors with histone H3F3A point mutations at G34 (NET-H3-G34) occur most often in cerebral hemispheres of teenagers and young adults, and have a generally adverse prognosis.
Felipe Andreiuolo, Tomo Lisner, Jozef Zlocha, Christof Kramm, Arend Koch, Brigitte Bison, Albane Gareton, Marc Zanello, Andreas Waha, Pascale Varlet, Torsten Pietsch   +10 more
doaj   +4 more sources

INSM1: A Novel Immunohistochemical and Molecular Marker for Neuroendocrine and Neuroepithelial Neoplasms [PDF]

American Journal of Clinical Pathology, 2015
Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms, which are sometimes malignant, although predicting metastasis is difficult. INSM1 is a transcription factor expressed transiently in embryonic neuroendocrine (NE) tissue, thought to coordinate termination of cell division with differentiation of NE and neuroepithelial cells. In adult tissues,
Jason N Rosenbaum, William M Rehrauer
exaly   +3 more sources

Intraocular Tumors in Horses: Diagnosis, Tumor Classification, Oncologic Assessment and Therapy [PDF]

Veterinary Sciences
Intraocular neoplasia in horses is rare and only few case reports and small case series exist. Intraocular neoplasia has various clinical signs and includes important differential diagnoses in ocular disease.
Christopher Ostendarp, Ann Kristin Barton   +1 more
doaj   +2 more sources

Neuroepithelial tumors of the central nervous system with EWSR1::PATZ1 fusion: a case report and literature review [PDF]

Frontiers in Oncology
Neuroepithelial tumors (NEpT) harboring EWSR::PATZ1 fusions remain an enigma. Initially described in sarcomas, these tumors display remarkable histomorphological diversity and unpredictable clinical behavior based on histologic or molecular features ...
João Felipe Lima Feldmann, João Henrique Lima Feldmann, Felipe Sales Canedo, Felipe Cicci Farinha Restini, Romulo Loss Mattedi, Luiz Guilherme Cernaglia A. de Lima, Olavo Feher   +6 more
doaj   +2 more sources

Discrepancies in diagnoses of neuroepithelial neoplasms [PDF]

Cancer, 2000
Valid and reliable diagnoses of disease are key both to meaningful epidemiologic and clinical investigations and to decision-making about appropriate treatment. One previous study highlighted the lack of precision in diagnosing primary brain tumors in a neuropathology referral practice.
Ken Aldape, Martha L. Simmons, Richard L. Davis, Rei Miike, John Wiencke, Geoffrey Barger, Marion Lee, Pengchin Chen, Margaret Wrensch   +8 more
openaire   +3 more sources

Long-term epilepsy associated-tumors (LEATs): what is new?

Arquivos de Neuro-Psiquiatria, 2023
Long-term epilepsy-associated tumors (LEATs) include a series of neoplasms that commonly occur in children, adolescents, or young adults, have an astrocytic or glioneuronal lineage, are histologically benign (WHO grade1) with a neocortical localization ...
Sergio Rosemberg
doaj   +1 more source

Case report: A unique presentation of a high-grade neuroepithelial tumor with EWSR1::PATZ1 fusion with diagnostic, molecular, and therapeutic insights

Frontiers in Oncology, 2023
BackgroundEWSR1::PATZ1 fusion tumors are exceedingly rare in the central nervous system with only 14 prior cases documented. PATZ1 fusion neuroepithelial tumors are beginning to be recognized as a distinct molecular class of neoplasms that most often ...
Andre Ene, Jing Di, Janna H. Neltner, Thomas Pittman, Susanne M. Arnold, Susanne M. Arnold, Jill M. Kolesar, Jill M. Kolesar, John L. Villano, John L. Villano, John L. Villano, Sara E. Bachert, Sara E. Bachert, Derek B. Allison, Derek B. Allison   +14 more
doaj   +1 more source

High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale

Indian Journal of Neurosurgery, 2023
Astroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed, as they are rarely encountered in clinical practice and share common ...
Mukta Meel, Ashok Gandhi, Arpita Jindal, Mukesh Kumar   +3 more
doaj   +1 more source

Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature

npj Precision Oncology, 2023
Pediatric neoplasms in the central nervous system (CNS) show extensive clinical and molecular heterogeneity and are fundamentally different from those occurring in adults. Molecular genetic testing contributes to accurate diagnosis and enables an optimal
Philipp Sievers, Martin Sill, Daniel Schrimpf, Zied Abdullaev, Andrew M. Donson, Jessica A. Lake, Dennis Friedel, David Scheie, Olli Tynninen, Tuomas Rauramaa, Kaisa L. Vepsäläinen, David Samuel, Rebecca Chapman, Richard G. Grundy, Kristian W. Pajtler, Arnault Tauziède-Espariat, Alice Métais, Pascale Varlet, Matija Snuderl, Thomas S. Jacques, Kenneth Aldape, David E. Reuss, Andrey Korshunov, Wolfgang Wick, Stefan M. Pfister, Andreas von Deimling, Felix Sahm, David T. W. Jones   +27 more
doaj   +1 more source