Results 41 to 50 of about 27,561 (220)

Early Onset Epilepsy Caused by Low-Grade Epilepsy-Associated Tumors and Focal Meningeal Involvement

Brain Sciences, 2020
Background: Low-grade epilepsy-associated neuroepithelial tumors (LEATs) are a frequent etiology in pediatric patients with epilepsy undergoing surgery.
Luca De Palma, Chiara Pepi, Alessandro De Benedictis, Nicola Pietrafusa, Angela Mastronuzzi, Antonella Cacchione, Giusy Carfì-Pavia, Camilla Rossi-Espagnet, Francesca Diomedi-Camassei, Sabrina Rossi, Antonio Napolitano, Andrea Carai, Giovanna Stefania Colafati, Daniela Longo, Paolo Curatolo, Federico Vigevano, Carlo Efisio Marras, Nicola Specchio   +17 more
doaj   +1 more source

Expression of stabilized β-catenin in differentiated neurons of transgenic mice does not result in tumor formation [PDF]

, 2002
Background: Medulloblastomas, embryonal tumors arising in the cerebellum, commonly contain mutations that activate Wnt signaling. To determine whether increased Wnt signaling in the adult CNS is sufficient to induce tumor formation, we created transgenic
MD Taylor, D Barel, AM Adesina, C Raffel, I Smyth, J Reifenberger, T Pietsch, CW Lam, MD Taylor, LV Goodrich, H Hahn, C Wetmore, M Peifer, RT Moon, P Polakis, H Huang, A Koch, CG Eberhart, RH Zurawel, RP Dahmen, SG Megason, A Chenn, AP McMahon, Y Wang, DR Borchelt, MT Furlong, JL Jankowsky, M van de Wetering, WL Perry 3rd, L Zeng, JJ Lucas, RB Halberg, N Harada, K Miyoshi, A Imbert, D Fults   +35 more
core   +2 more sources

Value of quantitative apparent diffusion coefficients in differentiating low-grade gliomas from mixed neuronal-glial tumors

World Neurosurgery: X, 2023
Purpose: To retrospectively assess if diffusion-weighted MR imaging (DWI) and quantitative apparent–diffusion coefficient (ADC) maps could be used to differentiate between low-grade gliomas (LGGs) and mixed neuronal–glial tumors (MNGTs including ...
Amit Agarwal, Sangam Kanekar, Shyam Sabat, Girish Bathla   +3 more
doaj   +1 more source

Craniopharyngiomas: immunohistochemical evaluation of prognostic factors [PDF]

, 2017
Craniopharyngiomas (CPs) are a heterogeneous group of benign but locally aggressive epithelial tumors arising within the sellar region, along the path of craniopharyngeal duct.
Somma, Anna
core   +1 more source

Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.: Tumor stem-like cells in pediatric brain tumors [PDF]

, 2011
International audienceBACKGROUND: Primitive brain tumors are the leading cause of cancer-related death in children. Tumor cells with stem-like properties (TSCs), thought to account for tumorigenesis and therapeutic resistance, have been isolated from ...
Bessette, Barbara, Bièche, Ivan, Bogeas, Alexandra, Boussin, François D, Cadusseau, Josette, Chneiweiss, Hervé, Daumas-Duport, Catherine, Dias-Morais, Amélia, Dos Reis Tavares, Silvina, Grill, Jacques, Junier, Marie-Pierre, Léonard, Nadine, Miquel, Catherine, Pflumio, Françoise, Puget, Stéphanie, Sainte-Rose, Christian, Silvestre, David Carlos, Studler, Jeanne-Marie, Surena, Anne-Laure, Susini, Aurélie, Thirant, Cécile, Varlet, Pascale, Villa, Chiara   +22 more
core   +6 more sources

Preliminary study of dysembryoplastic neuroepithelial tumor in relationship between its MRI types and epilepsy control following tumor removal

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To explore the relationship between MRI types and epilepsy control following tumor removal of dysembryoplastic neuroepithelial tumor (DNT). Methods The clinical and follow ⁃ up data of DNT cases were retrospectively collected from January 2012 ...
Hong⁃wei YIN, Yu⁃xiang WANG, Zhuo⁃qun LI, Zhi⁃han GUO, Huan⁃ting LI, Shi⁃fang LI, Yu⁃gong FENG, Zhao⁃jian LI   +7 more
doaj  

Position Paper on Olfactory Dysfunction [PDF]

, 2017
Background: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in
Altundag, A, Andrews, P, Cinghi, C, Costanzo, RM, Damm, M, Frasnelli, J, Gudziol, H, Gupta, N, Haehner, A, Holbrook, E, Hong, SC, Hornung, D, Hummel, T, Hüttenbrink, KB, Kamel, R, Kobayashi, M, Konstantinidis, I, Landis, BN, Leopold, DA, Macchi, A, Miwa, T, Moesges, R, Mueller, CA, Mullol, J, Ottaviano, G, Passali, GC, Philpott, C, Pinto, JM, Ramakrishnan, VJ, Rombaux, P, Roth, Y, Schlosser, RA, Shu, B, Soler, G, Stjärne, P, Stuck, BA, Vodicka, J, Welge-Luessen, A, Whitcroft, KL   +38 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The 2016 World Health Organization Classification of tumours of the Central Nervous System: what the paediatric neuroradiologist needs to know [PDF]

, 2016
The recently published 2016 World Health Organization (WHO) classification of tumours of the Central Nervous System (CNS) introduces a number of significant changes from the previous edition.
Carney, O, Chhabda, S, D'Arco, F, Jacques, TS, Mankad, K   +4 more
core   +1 more source

Functional Segregation of Epileptogenicity within the Human Amygdala

Annals of Neurology, EarlyView.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys, Julia Makhalova, Samuel Medina Villalon, Maria Fratello, Hugo Dary, Stanislas Lagarde, Francesca Pizzo, Agnès Trébuchon, Maxime Guye, Jean‐Philippe Ranjeva, Romain Carron, Didier Scavarda, Christian‐George Bénar, Bernard Giusiano, Fabrice Bartolomei   +14 more
wiley   +1 more source