Results 1 to 10 of about 643,956 (165)
This review addresses the specific contributions of nuclear medicine techniques, and especially positron emission tomography (PET), for diagnosis and management of brain tumors. (18)F-Fluorodeoxyglucose PET has particular strengths in predicting prognosis and differentiating cerebral lymphoma from nonmalignant lesions.
Herholz, Karl; id_orcid 0000-0002-8658-0151 +3 more
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At the same time that studies indicate an increase in the frequency of brain tumors, improvements in diagnosis and treatment have increased the clinician's ability to deal with these cancers. Dr. Posner, Chairman of the Department of Neurology at Memorial Sloan-Kettering Cancer Center in New York City, encourages physicians to be alert for symptoms of ...
E R, Laws, K, Thapar
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Patients with glioblastoma (GBM) have poor prognosis and limited treatment options, largely due to therapy resistance upon the induction of apoptosis.
Xiaodong Su +6 more
doaj +1 more source
Recent clinical trials utilizing antigen-pulsed dendritic cells (DCs) have demonstrated increased survival of vaccinated cancer patients. Besides, the cytoplasmic transduction peptide (CTP) not only has an excellent transcellular efficiency but also ...
Young-Hee Kim +9 more
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Background Glioblastoma (GBM) is a highly immunosuppressive and vascular malignant brain tumor. Current therapeutic strategies targeting tumor cells have limited efficacy because of the immunosuppressive microenvironment and vascularization.
Qing Zhang +5 more
doaj +1 more source
Personalized cancer vaccines targeting neoantigens arising from somatic missense mutations are currently being evaluated for the treatment of various cancers due to their potential to elicit a multivalent, tumor-specific immune response.
Adam M. Swartz +10 more
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Background Dendritic cell (DC) vaccine efficacy is directly related to the efficiency of DC migration to the lymph node after delivery to the patient.
Farhad Dastmalchi +10 more
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Glioblastoma (GBM) is a lethal brain cancer known for its potent immunosuppressive effects. Loss of Methylthioadenosine Phosphorylase (MTAP) expression, via gene deletion or epigenetic silencing, is one of the most common alterations in GBM. Here we show
Landon J. Hansen +7 more
doaj +1 more source
Recurrence of meningiomas is unpredictable by current invasive methods based on surgically removed specimens. Identification of patients likely to recur using noninvasive approaches could inform treatment strategy, whether intervention or monitoring.
Grayson A. Herrgott +34 more
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