Results 11 to 20 of about 643,956 (165)

Differential Predictors and Clinical Implications Associated With Long-Term Survivors in IDH Wildtype and Mutant Glioblastoma

Frontiers in Oncology, 2021
BackgroundGlioblastoma (GBM) is the most aggressive intracranial tumor which can be divided into two subtypes based on status of isocitrate dehydrogenase (IDH).
Haihui Jiang, Haihui Jiang, Kefu Yu, Yong Cui, Yong Cui, Xiaohui Ren, Xiaohui Ren, Mingxiao Li, Mingxiao Li, Guobin Zhang, Guobin Zhang, Chuanwei Yang, Chuanwei Yang, Xuzhe Zhao, Xuzhe Zhao, Qinghui Zhu, Qinghui Zhu, Song Lin, Song Lin, Song Lin   +19 more
doaj   +1 more source

Translational nanoparticle engineering for cancer vaccines

OncoImmunology, 2017
Conventional cancer treatments remain insufficient to treat many therapy-resistant tumors. Cancer vaccines attempt to overcome this resistance by activating the patient's immune system to eliminate tumor cells without the toxicity of systemic ...
Adam J. Grippin, Elias J. Sayour, Duane A. Mitchell   +2 more
doaj   +1 more source

Emerging trends in immunotherapy for pediatric sarcomas

Journal of Hematology & Oncology, 2019
While promising, immunotherapy has yet to be fully unlocked for the preponderance of cancers where conventional chemoradiation reigns. This remains particularly evident in pediatric sarcomas where standard of care has not appreciably changed in decades ...
Kyle A. Dyson, Brian D. Stover, Adam Grippin, Hector R. Mendez-Gomez, Joanne Lagmay, Duane A. Mitchell, Elias J. Sayour   +6 more
doaj   +1 more source

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Nature Communications, 2020
Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair,
Elisabeth Anne Adanma Obara, Diana Aguilar-Morante, Rikke Darling Rasmussen, Alex Frias, Kristoffer Vitting-Serup, Yi Chieh Lim, Kirstine Juul Elbæk, Henriette Pedersen, Lina Vardouli, Kamilla Ellermann Jensen, Jane Skjoth-Rasmussen, Jannick Brennum, Lucie Tuckova, Robert Strauss, Christoffel Dinant, Jiri Bartek, Petra Hamerlik   +16 more
doaj   +1 more source

IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells

Cell Division, 2020
Background Recurrence of Glioblastoma multiforme (GBM) seems to be the rule despite combination therapies. Cell invasion and cell proliferation are major reasons for recurrence of GBM. And insulin-like growth factor binding protein 5 (IGFBP5) is the most
Chengyuan Dong, Junwen Zhang, Sheng Fang, Fusheng Liu   +3 more
doaj   +1 more source

Combination of Immunotherapy and Radiotherapy for Recurrent Malignant Gliomas: Results From a Prospective Study

Frontiers in Immunology, 2021
BackgroundWorld Health Organization (WHO) grade IV glioma remains one of the most lethal tumors with a dismal prognosis and inevitable recurrence. We evaluated the safety and efficacy of immunotherapy with radiotherapy in this population of patients ...
Haihui Jiang, Haihui Jiang, Kefu Yu, Yong Cui, Yong Cui, Xiaohui Ren, Xiaohui Ren, Mingxiao Li, Mingxiao Li, Chuanwei Yang, Chuanwei Yang, Xuzhe Zhao, Xuzhe Zhao, Qinghui Zhu, Qinghui Zhu, Song Lin, Song Lin, Song Lin   +17 more
doaj   +1 more source

BRAIN TUMOR DETECTION AND BRAIN TUMOR AREA CALCULATION WITH MATLAB

Journal of Scientific Reports-A, 2023
Brain tumors that impair the functionality of the person in daily life occur for many different reasons. Treatment of a brain tumor depends on accurately identifying the type, location, size and boundaries of the tumor. Magnetic Resonance Imaging (MRI) technique is used to diagnose the disease.
Burak KAPUSIZ, Yusuf UZUN, Sabri KOÇER, Özgür DÜNDAR   +3 more
openaire   +3 more sources

Brain Tumor Imaging [PDF]

Journal of Clinical Oncology, 2017
Modern imaging techniques, particularly functional imaging techniques that interrogate some specific aspect of underlying tumor biology, have enormous potential in neuro-oncology for disease detection, grading, and tumor delineation to guide biopsy and resection; monitoring treatment response; and targeting radiotherapy.
Brindle, Kevin M., Izquierdo-García, José L., Lewis, David Y., Mair, Richard J., Wright, Alan J.   +4 more
openaire   +2 more sources

Myelopoiesis during Solid Cancers and Strategies for Immunotherapy

Cells, 2021
Our understanding of the relationship between the immune system and cancers has undergone significant discovery recently. Immunotherapy with T cell therapies and checkpoint blockade has meaningfully changed the oncology landscape.
Tyler J. Wildes, Bayli DiVita Dean, Catherine T. Flores   +2 more
doaj   +1 more source

The Visual Acuity Outcome and Relevant Factors Affecting Visual Improvement in Pediatric Sporadic Chiasmatic–Hypothalamic Glioma Patients Who Received Surgery

Frontiers in Neurology, 2020
Background: The role and effectiveness of primary surgical treatment for sporadic chiasmatic–hypothalamic glioma (CHG) are not clear. The present study was to describe sporadic CHG visual acuity (VA) outcomes after surgery and to analyze the relevant ...
Chihyi Liao, Chihyi Liao, Heng Zhang, Heng Zhang, Zhiming Liu, Zhiming Liu, Zhe Han, Zhe Han, Chunde Li, Chunde Li, Jian Gong, Jian Gong, Wei Liu, Wei Liu, Zhenyu Ma, Zhenyu Ma, Yongji Tian, Yongji Tian   +17 more
doaj   +1 more source