Results 31 to 40 of about 3,399,085 (314)

Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas

Nature Communications, 2023
Recurrence of meningiomas is unpredictable by current invasive methods based on surgically removed specimens. Identification of patients likely to recur using noninvasive approaches could inform treatment strategy, whether intervention or monitoring.
Grayson A. Herrgott, James M. Snyder, Ruicong She, Tathiane M. Malta, Thais S. Sabedot, Ian Y. Lee, Jacob Pawloski, Guilherme G. Podolsky-Gondim, Karam P. Asmaro, Jiaqi Zhang, Cara E. Cannella, Kevin Nelson, Bartow Thomas, Ana C. deCarvalho, Laura A. Hasselbach, Kelly M. Tundo, Rehnuma Newaz, Andrea Transou, Natalia Morosini, Victor Francisco, Laila M. Poisson, Dhananjay Chitale, Abir Mukherjee, Maritza S. Mosella, Adam M. Robin, Tobias Walbert, Mark Rosenblum, Tom Mikkelsen, Steven Kalkanis, Daniela P. C. Tirapelli, Daniel J. Weisenberger, Carlos G. Carlotti, Jack Rock, Ana Valeria Castro, Houtan Noushmehr   +34 more
doaj   +1 more source

Differential Predictors and Clinical Implications Associated With Long-Term Survivors in IDH Wildtype and Mutant Glioblastoma

Frontiers in Oncology, 2021
BackgroundGlioblastoma (GBM) is the most aggressive intracranial tumor which can be divided into two subtypes based on status of isocitrate dehydrogenase (IDH).
Haihui Jiang, Haihui Jiang, Kefu Yu, Yong Cui, Yong Cui, Xiaohui Ren, Xiaohui Ren, Mingxiao Li, Mingxiao Li, Guobin Zhang, Guobin Zhang, Chuanwei Yang, Chuanwei Yang, Xuzhe Zhao, Xuzhe Zhao, Qinghui Zhu, Qinghui Zhu, Song Lin, Song Lin, Song Lin   +19 more
doaj   +1 more source

Intracranial transplantation of the tumor induced by adenovirus type 12 in Syrian hamster--an experimental brain tumor model [PDF]

, 1971
A method of intracranial transplantation of the tumor induced by adenovirus type 12 in syrian hamster has been described. The incidence of intracranial tumor development was 86 (90.5 %) out of 95 animals and the average survival time and tumor size at ...
Tabuchi, Kazuo
core   +1 more source

Translational nanoparticle engineering for cancer vaccines

OncoImmunology, 2017
Conventional cancer treatments remain insufficient to treat many therapy-resistant tumors. Cancer vaccines attempt to overcome this resistance by activating the patient's immune system to eliminate tumor cells without the toxicity of systemic ...
Adam J. Grippin, Elias J. Sayour, Duane A. Mitchell   +2 more
doaj   +1 more source

The Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade II Cerebral Gliomas in Adults: Version 2019.01 [PDF]

, 2019
BACKGROUND: There was no practical guideline for the management of patients with central nervous system tumor in Korea for many years. Thus, the Korean Society for Neuro-Oncology (KSNO), a multidisciplinary academic society, has developed the guideline
조재호, 김세훈, 윤홍인, 강석구, 장종희, 김의현   +5 more
core   +1 more source

Emerging trends in immunotherapy for pediatric sarcomas

Journal of Hematology & Oncology, 2019
While promising, immunotherapy has yet to be fully unlocked for the preponderance of cancers where conventional chemoradiation reigns. This remains particularly evident in pediatric sarcomas where standard of care has not appreciably changed in decades ...
Kyle A. Dyson, Brian D. Stover, Adam Grippin, Hector R. Mendez-Gomez, Joanne Lagmay, Duane A. Mitchell, Elias J. Sayour   +6 more
doaj   +1 more source

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Nature Communications, 2020
Cancer stem cells can evade treatment. Here, the authors perform an in vitro screen to identify proteins that are involved in protecting glioma cancer stem cells from therapy and find that SPT6 increases BRCA1 expression and drives error-free DNA repair,
Elisabeth Anne Adanma Obara, Diana Aguilar-Morante, Rikke Darling Rasmussen, Alex Frias, Kristoffer Vitting-Serup, Yi Chieh Lim, Kirstine Juul Elbæk, Henriette Pedersen, Lina Vardouli, Kamilla Ellermann Jensen, Jane Skjoth-Rasmussen, Jannick Brennum, Lucie Tuckova, Robert Strauss, Christoffel Dinant, Jiri Bartek, Petra Hamerlik   +16 more
doaj   +1 more source

Angioleiomyoma in the Orbital Apex: A Case Report [PDF]

, 2019
A 56-year woman presented eyeball pain and blurred vision. MRI revealed a small well-delineated solid tumor in the apex of right orbit with optic nerve compression.
김세훈, 문주형, 장종희, 김의현, 김선호   +4 more
core   +1 more source

IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells

Cell Division, 2020
Background Recurrence of Glioblastoma multiforme (GBM) seems to be the rule despite combination therapies. Cell invasion and cell proliferation are major reasons for recurrence of GBM. And insulin-like growth factor binding protein 5 (IGFBP5) is the most
Chengyuan Dong, Junwen Zhang, Sheng Fang, Fusheng Liu   +3 more
doaj   +1 more source

Combination of Immunotherapy and Radiotherapy for Recurrent Malignant Gliomas: Results From a Prospective Study

Frontiers in Immunology, 2021
BackgroundWorld Health Organization (WHO) grade IV glioma remains one of the most lethal tumors with a dismal prognosis and inevitable recurrence. We evaluated the safety and efficacy of immunotherapy with radiotherapy in this population of patients ...
Haihui Jiang, Haihui Jiang, Kefu Yu, Yong Cui, Yong Cui, Xiaohui Ren, Xiaohui Ren, Mingxiao Li, Mingxiao Li, Chuanwei Yang, Chuanwei Yang, Xuzhe Zhao, Xuzhe Zhao, Qinghui Zhu, Qinghui Zhu, Song Lin, Song Lin, Song Lin   +17 more
doaj   +1 more source