Results 51 to 60 of about 3,399,085 (314)

Magnetic resonance imagining-based automated brain tumor detection using deep learning techniques

, 2023
brain tumor refers to an accumulation or growth of anomalous cells in the brain. The mass can either be benign (noncancerous) or malignant (cancerous). Cancerous brain tumors are the source of morbidity for which diagnosis and treatment require extensive
Subasi, Abdulhamit, Panigrahi, Abhranta
core   +1 more source

A-Disintegrin and metalloprotease (ADAM) 10 and 17 promote self-renewal of brain tumor sphere forming cells [PDF]

, 2012
It has been proposed that gliomas contain a subpopulation of 'Brain Tumor Stem Cells' (BTSCs), which demonstrate resistance to conventional therapies.
Siney, Elodie J, Sampson, Jessica M., Sampson, Jessica M, Jones, Louise M, Bulstrode, Harry, Siney, Elodie J., Gray, William Peter, Ludwig, Andreas, Willaime-Morawek, Sandrine, Gray, William P, Jones, Louise M., Gray, William P.   +11 more
core   +1 more source

Functional genomics of brain development and developmentally related brain disease in "Drosophila" [PDF]

, 2004
One of the fundamental challenges in basic neuroscience is to understand the molecular genetic networks associated with building the brain. As malfunction in these genetic pathways can lead to disorders like cancer, brain development is also a crucial ...
Loop, Thomas
core   +1 more source

Local Drug Delivery Strategies for Glioblastoma Treatment

, 2022
Glioblastoma multiforme (GBM) is a brain tumor notorious for its malignancy. The key reason for the limited efficacy of standard treatment is the high recurrence rate of GBM, even after surgical resection. Hence, intensive postsurgical chemical therapies,
Gi Doo Cha, Choi, Seung Hong, Kim, Dae-Hyeong, Kim, Dae Hyeong, Jung, Sonwoo, Seung Hong Choi, Sonwoo Jung, Dae-Hyeong Kim, Cha, Gi Doo   +8 more
core   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Higher Cho/NAA Ratio in Postoperative Peritumoral Edema Zone Is Associated With Earlier Recurrence of Glioblastoma

Frontiers in Neurology, 2020
Objective: To explore the prognostic significance of metabolic parameters in postoperative peritumoral edema zone (PEZ) of patients with glioblastoma (GBM) based on proton magnetic resonance spectroscopy (MRS).Methods: The postoperative MRS data of 67 ...
Yong Cui, Yong Cui, Wei Zeng, Haihui Jiang, Haihui Jiang, Xiaohui Ren, Xiaohui Ren, Song Lin, Song Lin, Yanzhu Fan, Yanzhu Fan, Yapeng Liu, Yapeng Liu, Jizong Zhao, Jizong Zhao   +14 more
doaj   +1 more source

Beyond the Document: A Single‐Center Qualitative Study of Survivorship Care Plan Barriers and Opportunities Across Pediatric Oncology Stakeholders

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivorship care plans (SCPs) summarize cancer treatment and guide risk‐based follow‐up for cancer survivors, yet remain difficult to create, share, and use. Stakeholder perspectives are needed to inform usable approaches.
Molly S. Talman, Emma Fleisher, Megan E. Salwei, Debra Friedman, Laurie Novak   +4 more
wiley   +1 more source

CD70 CAR-T cells empowered by TS-2021 through ex vivo transduction show potent antitumor efficacy against glioblastoma

Journal of Experimental & Clinical Cancer Research
Background Chimeric antigen receptor (CAR) T-cell therapy has shown limited efficacy in glioblastoma (GBM) due to tumor antigen heterogeneity and the immunosuppressive microenvironment.
Sheng Fang, Jiankun Wu, Yida Liu, Peiwen Wang, Guiqiang Yuan, Jiajia Gao, Wenxin Zhang, Junwen Zhang, Fusheng Liu   +8 more
doaj   +1 more source