Results 51 to 60 of about 643,956 (165)

Opposite Roles of Furin and PC5A in N-Cadherin Processing

Neoplasia: An International Journal for Oncology Research, 2012
We recently demonstrated that lack of Furin-processing of the N-cadherin precursor (proNCAD) in highly invasive melanoma and brain tumor cells results in the cell-surface expression of a nonadhesive protein favoring cell migration and invasion in vitro ...
Deborah Maret, Mohamad Seyed Sadr, Emad Seyed Sadr, David R Colman, Rolando F Del Maestro, Nabil G Seidah   +5 more
doaj   +1 more source

Amide proton transfer-weighted CEST MRI for radiotherapy target delineation of glioblastoma: a prospective pilot study

European Radiology Experimental
Background Extensive glioblastoma infiltration justifies a 15-mm margin around the gross tumor volume (GTV) to define the radiotherapy clinical target volume (CTV).
Patrick L. Y. Tang, Alejandra Méndez Romero, Remi A. Nout, Caroline van Rij, Cleo Slagter, Annemarie T. Swaak-Kragten, Marion Smits, Esther A. H. Warnert   +7 more
doaj   +1 more source

IDH Mutations in Glioma: Molecular, Cellular, Diagnostic, and Clinical Implications

Biology
In 2021, the World Health Organization classified isocitrate dehydrogenase (IDH) mutant gliomas as a distinct subgroup of tumors with genetic changes sufficient to enable a complete diagnosis.
Kristian A. Choate, Evan P. S. Pratt, Matthew J. Jennings, Robert J. Winn, Paul B. Mann   +4 more
doaj   +1 more source

BRAIN TUMOR

The Journal of Nervous and Mental Disease, 1920
n ...
openaire   +2 more sources

Bony Tumor of Brain [PDF]

The American Journal of the Medical Sciences, 1885
n ...
openaire   +1 more source

Induction and Characterization of Human Glioma Clones With Different Radiosensitivities

Neoplasia: An International Journal for Oncology Research, 1999
To facilitate investigation of the molecular mechanisms of tumor cell radiosensitivities, we have generated a set of clones with different radiosensitivities from a human glioma cell line U-251 MG-Ho.
Jingli Wang, Lily Hu, Nalin Gupta, Tod Shamseldin, Tomoko Ozawa, Jack Klem, Monika Cardell, Dennis F. Deen   +7 more
doaj   +1 more source

Correction: HIF-α activation by the prolyl hydroxylase inhibitor roxadustat suppresses chemoresistant glioblastoma growth by inducing ferroptosis

Cell Death and Disease, 2023
Xiaodong Su, Yuan Xie, Junwen Zhang, Mingxin Li, Qing Zhang, Guishan Jin, Fusheng Liu   +6 more
doaj   +1 more source

MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells

Stem Cell Research, 2015
Neural stem cell (NSC)-based carriers have been presented as promising therapeutic tools for the treatment of infiltrative brain tumors due to their intrinsic tumor homing property.
Nikita G. Alexiades, Brenda Auffinger, Chung Kwon Kim, Tanwir Hasan, Gina Lee, Marc Deheeger, Alex L. Tobias, Janice Kim, Irina Balyasnikova, Maciej S. Lesniak, Karen Aboody, Atique U. Ahmed   +11 more
doaj   +1 more source

Protoporphyrin IX plasma and blood pharmacokinetics and brain tumor distribution determined by a validated LC–MS/MS method

Scientific Reports
Protoporphyrin IX (PPIX) is a fluorescent metabolite in the heme biosynthesis pathway, and cancer cells accumulate it when 5-aminolevulinic acid (5-ALA), a precursor, is administered. In the U.S., 5-ALA is approved for visualizing high-grade gliomas (HGG)
William Knight, Tigran Margaryan, Kamal Shaik, Nader Sanai, Artak Tovmasyan   +4 more
doaj   +1 more source

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

Nature Communications, 2018
Glioblastoma can be classified based on IDH and TERT promoter mutations, but ~20% of glioblastoma do not have these mutations (TERT p WT-IDH WT glioblastoma).
Bill H. Diplas, Xujun He, Jacqueline A. Brosnan-Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric S. Lipp, Paula K. Greer, Rui Yang, Anthony J. Rizzo, Fausto J. Rodriguez, Allan H. Friedman, Henry S. Friedman, Sizhen Wang, Yiping He, Roger E. McLendon, Darell D. Bigner, Yuchen Jiao, Matthew S. Waitkus, Alan K. Meeker, Hai Yan   +23 more
doaj   +1 more source