Results 91 to 100 of about 4,375 (200)

Comparison of ovarian mRNA expression levels in wild and hatchery-produced greater amberjack Seriola dumerili

Scientific Reports
The greater amberjack Seriola dumerili is a promising candidate for aquaculture production. This study compares the ovary transcriptome of greater amberjack sampled in the wild (WILD) with hatchery-produced breeders reared in aquaculture sea cages in the
Anna Lavecchia, Caterina De Virgilio, Luigi Mansi, Caterina Manzari, Constantinos C. Mylonas, Ernesto Picardi, Chrysovalentinos Pousis, Sharon N. Cox, Gianluca Ventriglia, Rosa Zupa, Graziano Pesole, Aldo Corriero   +11 more
doaj   +1 more source

Mutational spectrum of autosomal recessive limb-girdle muscular dystrophies in a cohort of 112 Iranian patients and reporting of a possible founder effect

Orphanet Journal of Rare Diseases, 2020
Background Limb-girdle muscular dystrophies are a group of genetically heterogeneous diseases that are inherited in both autosomal dominant (LGMDD) and autosomal recessive forms (LGMDR), the latter is more common especially in populations with high ...
Marzieh Mojbafan, Reza Bahmani, Samira Dabbagh Bagheri, Zohreh Sharifi, Sirous Zeinali   +4 more
doaj   +1 more source

Epidemiology, causes, evolution and outcome in a single-center cohort of 1116 critically ill patients with hypoxic hepatitis [PDF]

, 2018
Background: Hypoxic hepatitis (HH) is a type of acute hepatic injury that is histologically characterized by centrilobular liver cell necrosis and that is caused by insufficient oxygen delivery to the hepatocytes.
Benoit, Dominique, Colpaert, Kirsten, Decruyenaere, Alexander, Decruyenaere, Johan, Van Coile, Laura, Van den broecke, Astrid, Van Vlierberghe, Hans   +6 more
core   +2 more sources

Inpatient Schema Therapy: Results of a Multiple Baseline Case Series Study

Clinical Psychology &Psychotherapy, Volume 33, Issue 1, January/February 2026.
ABSTRACT This study tested a 10‐week multidisciplinary schema therapy inpatient treatment protocol for patients with personality disorders, including two individual and two group sessions per week, supportive sessions with nurse cotherapists, as well as art, music, sports group and individual body therapy.
Matias Valente, Ilona An Voort, Lisa Mazurczyk, Thomas Müller‐Tasch, Eckhard Roediger, Stefan Smesny, Charlotte van den Hengel, Arnoud Arntz   +7 more
wiley   +1 more source

Full-length Dysferlin Transfer by the Hyperactive Sleeping Beauty Transposase Restores Dysferlin-deficient Muscle

Molecular Therapy: Nucleic Acids, 2016
Dysferlin-deficient muscular dystrophy is a progressive disease characterized by muscle weakness and wasting for which there is no treatment. It is caused by mutations in DYSF, a large, multiexonic gene that forms a coding sequence of 6.2 kb.
Helena Escobar, Verena Schöwel, Simone Spuler, Andreas Marg, Zsuzsanna Izsvák   +4 more
doaj   +1 more source

Large-scale discovery of enhancers from human heart tissue. [PDF]

, 2011
Development and function of the human heart depend on the dynamic control of tissue-specific gene expression by distant-acting transcriptional enhancers.
Afzal, Veena, Akiyama, Jennifer A, Black, Brian L, Blow, Matthew J, Bristow, James, Holt, Amy, Jensen, Brian C, Kaplan, Tommy, May, Dalit, McCulley, David J, Pennacchio, Len A, Plajzer-Frick, Ingrid, Rubin, Edward M, Shoukry, Malak, Simpson, Paul C, Visel, Axel, Wright, Crystal   +16 more
core  

The Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiae [PDF]

, 2016
Sporulation of Saccharomyces cerevisiae is a developmental process in which an ascus containing four haploid spores forms from a diploid cell. During this process, newly formed membrane structures called prospore membranes extend along the nuclear ...
Gao Xiao-Dong, Inoue Ichiro, Nakamura Shugo, Nakamura Tsuyoshi S., Nakanishi Hideki, Okumura Yuuya, Suda Yasuyuki, Tachikawa Hiroyuki, Takahashi Tetsuo, Tanaka Takayuki, 須田 恭之   +10 more
core   +1 more source

Brain of miyoshi myopathy/dysferlinopathy patients presents with structural and metabolic anomalies

Scientific Reports
Miyoshi myopathy/dysferlinopathy (MMD) is a rare muscle disease caused by DYSF gene mutations. Apart from skeletal muscles, DYSF is also expressed in the brain.
Petra Hnilicova, Marian Grendar, Monika Turcanova Koprusakova, Alzbeta Trancikova Kralova, Jana Harsanyiova, Martin Krssak, Ivica Just, Nadezda Misovicova, Martina Hikkelova, Jan Grossmann, Peter Spalek, Iveta Meciarova, Egon Kurca, Norbert Zilka, Kamil Zelenak, Wolfgang Bogner, Martin Kolisek   +16 more
doaj   +1 more source

A comparison of AAV strategies distinguishes overlapping vectors for efficient systemic delivery of the 6.2 kb Dysferlin coding sequence

Molecular Therapy: Methods & Clinical Development, 2015
Recombinant adeno-associated virus (rAAV) is currently the best vector for gene delivery into the skeletal muscle. However, the 5-kb packaging size of this virus is a major obstacle for large gene transfer.
Marina Pryadkina, William Lostal, Nathalie Bourg, Karine Charton, Carinne Roudaut, Matthew L Hirsch, Isabelle Richard   +6 more
doaj   +1 more source

Proteinfehlfaltung als Ursache der Muskeldystrophie Dysferlinopathie: Das Mausmodell Dysf-MMex38

, 2018
The aim of this thesis was the characterization of the newly generated MMex38- mouse model. It is the first animal model for the limb girdle muscular dystrophy dysferlinopathy, which is caused by a missense mutation and protein misfolding. Dysferlinopathy is a rare autosomal recessive muscle disease.
openaire   +1 more source