Results 91 to 100 of about 1,945 (206)

Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries [PDF]

, 2017
Fibrinogen is an essential agent involved in maintaining pregnancy and coagulation. Since inherited fibrinogen disorders introduce greater risks for conditions such as placental abruption and postpartum hemorrhage, careful prenatal and perinatal ...
Hiroshi Miyoshi, Kumi Oshima, Norifumi Tanaka, Satoshi Urabe, Yoshiki Kudo, Yuko Teraoka   +5 more
core   +3 more sources

Genetic analyses of novel compound heterozygous hypodysfibrinogenemia, Tsukuba I: FGG c.1129+62_65 del AATA and FGG c.1299+4 del A [PDF]

, 2016
Epub 2016 Nov 5Introduction: Wefound a novel hypodysfibrinogenemia designated Tsukuba I caused by compound heterozygous nucleotide deletionswith FGG c. 1129+ 62_ 65 del AATA and FGG c. 1299+ 4 del A on different alleles.
Arai, Shinpei, Honda, Takayuki, Ikeda, Minami, Mukai, Saki, Nagata, Kazuhiro, Okumura, Nobuo, Sugano, Mitsutoshi   +6 more
core   +1 more source

Hereditary dysfibrinogenemia.

Clinical Chemistry, 1985
Abstract Inherited qualitative abnormalities of fibrinogen have been documented in more than 100 families. These dysfibrinogenemias usually are clinically silent, but in some cases are associated with bleeding, thrombosis, or defective wound healing.
openaire   +2 more sources

Fibrin-bound thrombin determines clot structure and blood thrombogenicity in normofibrinogenemia and dysfibrinogenemia

Haematologica
In thrombosis and haemostasis, coagulation and platelet activation pathways culminate to form solid fibrin clots, which can become vaso-occlusive or prevent excessive bleeding.
Siyu Sun, Mark Roest, Rolf T. Urbanus, Elena Campello, Sarah Beck, Cristiana Bulato, Simon D. Connell, Philip G. de Groot, Timea Feller, Dana Huskens, Joke Konings, Rita Marchi, Harmen Middelveld, Patricia Oftering, Bernhard Nieswandt, Alessandro Casini, Robert A.S. Ariens, Paolo Simioni, Johan W.M. Heemskerk, Bas de Laat   +19 more
doaj   +1 more source

In vitro expression demonstrates impaired secretion of the gamma Asn319, Asp320 deletion variant fibrinogen [PDF]

, 2005
This article is not an exact copy of the original published article in [THROMBOSIS AND HAEMOSTASIS]. The definitive publisher-authenticated version of [THROMBOSIS AND HAEMOSTASIS 94;53-59,2005] is available online at: [http://www.schattauer.de ...
Kani, S, Katsuyama, T, Lord, ST, Okumura, N, Ota, H, Terasawa, F, Tozuka, M   +6 more
core   +1 more source

Manipulating the quality control pathway in transfected cells: low temperature allows rescue of secretion-defective fibrinogen mutants

Haematologica, 2008
Background Congenital afibrinogenemia is characterized by the absence of fibrinogen, a hexamer composed of two copies of three polypeptides, Aα. Bβ and γ. The disease is caused by mutations in one of the three fibrinogen-encoding genes, FGA, FGB and FGG.
Dung Vu, Corinne Di Sanza, Marguerite Neerman-Arbez   +2 more
doaj   +1 more source

Recombinant gamma T305A fibrinogen indicates severely impaired fibrin polymerization due to the aberrant function of hole 'a' and calcium binding sites [PDF]

, 2014
Introduction: We examined a 6-month-old girl with inherited fibrinogen abnormality and no history of bleeding or thrombosis. Routine coagulation screening tests showed a markedly low level of plasma fibrinogen determined by functional measurement and ...
Arai, Shinpei, Ikeda, Minami, Kobayashi, Tamaki, Mukai, Saki, Okumura, Nobuo, Takezawa, Yuka, Terasawa, Fumiko   +6 more
core   +1 more source

Acquired dysfibrinogenemia in atherosclerotic vascular disease [PDF]

Polish Archives of Internal Medicine, 2011
Acquired qualitative abnormalities of fibrinogen molecules, termed acquired dysfibrinogenemia, have been demonstrated in several disease states mostly related to prothrombotic tendency, including multiple myeloma and liver disease. Fibrin is abundant in atherosclerotic plaques.
openaire   +2 more sources

Laboratory investigation of thrombophilia [PDF]

Journal of Medical Biochemistry, 2014
Laboratory investigation of thrombophilia is aimed at detecting the well-established hereditary and acquired causes of venous thromboembolism, including activated protein C resistance/factor V Leiden mutation, prothrombin G20210A mutation, deficiencies ...
Margetić Sandra
doaj  

Relationship between the dual platelet‐inhibited ROTEM® Sigma FIBTEM assay and Clauss fibrinogen during postpartum haemorrhage

Anaesthesia, Volume 80, Issue 1, Page 104-106, January 2025.
Sarah F. Bell, Hazel Taylor, Philip Pallmann, Peter Collins, on behalf of the OBS Cymru collaborators (online Supporting Information Appendix S1)   +4 more
wiley   +1 more source