Results 1 to 10 of about 2,148 (125)

Stage IIIC Bilateral Dysgerminoma in a 16-Year-Old Phenotypic Female With 46,XY Complete Gonadal Dysgenesis and Primary Amenorrhea: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Dysgerminoma, the most common malignant ovarian germ cell tumor, has a significantly increased incidence in individuals with 46,XY complete gonadal dysgenesis (Swyer syndrome). However, primary amenorrhea is the hallmark presentation of Swyer syndrome in adolescence.
Vasef M, Afshar Moghaddam N, Raoufi M, Iranipour M, Moghadami S.   +4 more
europepmc   +2 more sources

Advanced Ovarian Dysgerminoma With Supraclavicular Lymph Node Metastasis and Peritoneal Carcinomatosis: A Rare Case Report. [PDF]

Clin Case Rep
ABSTRACT Ovarian dysgerminoma is a rare, highly chemo‐sensitive germ cell tumor usually presenting early. We report a FIGO stage IVB case with supraclavicular lymph node metastasis and peritoneal carcinomatosis in a 31‐year‐old woman. Diagnosis was based on classical histopathology.
Khaniya B, Shah S, Adhikari D, Acharya A, Poudel A, Gautam S.   +5 more
europepmc   +2 more sources

Malignant Ovarian Germ Cell Tumor-Survival and Reproductive Outcomes and Patterns of Relapse. [PDF]

Cancer Med
BLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Dey S, Anne S, Rath S, Nandhana R, Gulia S, Dash B, Menon S, Rekhi B, Baheti A, Sable N, Popat P, Tandon S, Ghosh K, Gurram L, Parab SS, Logkumer AN, Jhadhav S, Chopra S, Surappa ST, Bansal V, Balsarkar G, Deodhar K, Maheshwari A, Ghosh J, Gupta S.   +24 more
europepmc   +2 more sources

Clinical Features of Malignant Ovarian Germ Cell Tumors According to Demographic and Pathologic Characteristics. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Malignant ovarian germ cell tumors (MOGCTs) are aggressive cancers affecting mainly young women, in whom fertility preservation is important. Diagnosis is often delayed because early symptoms are non‐specific, leading to advanced disease or emergency surgery that may limit optimal staging and fertility‐sparing treatment. As
Agah J, Navipour E, Akhavan S, Norouzi S.   +3 more
europepmc   +2 more sources

Advanced-Stage Gonadal Dysgerminoma in a Patient With a Previous Diagnosis of Familial Swyer Syndrome: A Very Rare Genetic Entity. [PDF]

Case Rep Med
Introduction Swyer syndrome is a genetic abnormality characterized by a 46,XY karyotype in a phenotypically female individual. Affected individuals typically have average or tall stature, unambiguous genitalia at birth, the presence of Müllerian structures, and bilateral streak gonads.
Oğlak SC, Söğütçü N, Akgöl S, Adıgüzel Ö, Ateş Eminoğlu HE, Güzel G, Balcı V, Acar E, Acar A, Bozan F.   +9 more
europepmc   +2 more sources

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T-Cell Exhaustion in Dysgerminoma. [PDF]

Cancer Sci
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Nakashima M, Iwasaki T, Katayama Y, Shimo M, Takigawa K, Shimada N, Matsushita M, Kuwamoto S, Sato S, Toya M, Miyawaki K, Akashi K, Kato K, Oda Y.   +13 more
europepmc   +2 more sources

Dysgerminoma of the Ovary [PDF]

BMJ, 1950
Abstract Despite the patient's involuntary sterility, there were no physical findings to substantiate a condition of hypoplasia of the gonads as the early case reports attempted to stress. This case, however, serves to emphasize that dysgerminoma does occur in the olderage groups and can behave in a biologically highly malignant fashion.
openaire   +4 more sources

Anaplastic dysgerminoma [PDF]

Cancer, 1978
A rare case of rapidly evolving dysgerminoma produced death by tumor in less than two months after onset of symptoms. It is important to recall that dysgerminoma possesses considerable malignant potential, which infrequently is manifested by rapidly progressive disease.
J J, Gillespie, L K, Arnold
openaire   +2 more sources

Bilateral Gonadoblastoma in a 12-Year-Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case. [PDF]

Clin Case Rep
ABSTRACT This case of a 12‐year‐old patient who developed bilateral gonadoblastoma 4 years after treatment for Wilms tumor highlights the importance of rigorous, risk‐adapted long‐term surveillance and careful evaluation of incidental gonadal findings, even in asymptomatic patients.
Quraish A, Khouli H, Daraghmeh Y, Mosleh S, Bustame S.   +4 more
europepmc   +2 more sources

Dysgerminoma of the ovary [PDF]

Cancer, 1979
From 1938 to 1977, 21 patients with pure dysgerminoma were treated at Memorial and James Ewing Hospitals, now Memorial Sloan-Kettering Cancer Center. Twelve patients were considered to have their initial therapy begun or completed at our institution. Eleven (91.7%) of 12 patients were found free of disease from 2 to 38 years (median 6 years).
J H, Freel, J F, Cassir, V K, Pierce, J, Woodruff, J L, Lewis   +4 more
openaire   +2 more sources