Advanced Ovarian Dysgerminoma With Supraclavicular Lymph Node Metastasis and Peritoneal Carcinomatosis: A Rare Case Report. [PDF]
ABSTRACT Ovarian dysgerminoma is a rare, highly chemo‐sensitive germ cell tumor usually presenting early. We report a FIGO stage IVB case with supraclavicular lymph node metastasis and peritoneal carcinomatosis in a 31‐year‐old woman. Diagnosis was based on classical histopathology.
Khaniya B +5 more
europepmc +2 more sources
Malignant Ovarian Germ Cell Tumor-Survival and Reproductive Outcomes and Patterns of Relapse. [PDF]
BLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Dey S +24 more
europepmc +2 more sources
Clinical Features of Malignant Ovarian Germ Cell Tumors According to Demographic and Pathologic Characteristics. [PDF]
ABSTRACT Background and Aims Malignant ovarian germ cell tumors (MOGCTs) are aggressive cancers affecting mainly young women, in whom fertility preservation is important. Diagnosis is often delayed because early symptoms are non‐specific, leading to advanced disease or emergency surgery that may limit optimal staging and fertility‐sparing treatment. As
Agah J +3 more
europepmc +2 more sources
Advanced-Stage Gonadal Dysgerminoma in a Patient With a Previous Diagnosis of Familial Swyer Syndrome: A Very Rare Genetic Entity. [PDF]
Introduction Swyer syndrome is a genetic abnormality characterized by a 46,XY karyotype in a phenotypically female individual. Affected individuals typically have average or tall stature, unambiguous genitalia at birth, the presence of Müllerian structures, and bilateral streak gonads.
Oğlak SC +9 more
europepmc +2 more sources
Imaging Findings in Dysgerminoma in a Case of 46 XY, Complete Gonadal Dysgenesis (Swyer syndrome) [PDF]
A 46 XY pure gonadal dysgenesis also known as Swyer syndrome. These patients are phenotypic females with normal female external genitalia and absent testicular tissue.
Pratiksha Yadav +2 more
doaj +1 more source
Dysgerminoma comprises 3%–5% among ovarian malignancies, mostly seen in adolescent and early adult women. The recurrence rate is approximately 10%–20%, occurring within 2 years of diagnosis, and has been reported that more than 75% occur in the 1st year.
Amor Mae M. Pasigon, Jimmy A. Billod
doaj +1 more source
Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T-Cell Exhaustion in Dysgerminoma. [PDF]
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Nakashima M +13 more
europepmc +2 more sources
An Incidental Finding of Bilateral Dysgerminoma During Cesarean Section: Dilemmas in Management [PDF]
Dysgerminoma is an uncommon malignant tumour arising from germ cells of ovary. It occurs mostly in the reproductive age group. Its association with pregnancy is rare. Its management remains a challenge especially in an unsuspected case.
Mamta Gupta, Rita Jindal, Vandana Saini
doaj +1 more source
Dysgerminoma of the Ovary [PDF]
Abstract Despite the patient's involuntary sterility, there were no physical findings to substantiate a condition of hypoplasia of the gonads as the early case reports attempted to stress. This case, however, serves to emphasize that dysgerminoma does occur in the olderage groups and can behave in a biologically highly malignant fashion.
openaire +4 more sources
Ovarian dysgerminoma with Müllerian anomaly: a case report [PDF]
Müllerian anomalies are rare deformities in women, and only a few cases concerning gynecologic malignancies arising in patients with congenital uterine malformations have been reported. Herein, we present the case of a 34-year-old woman with dysgerminoma
Ha Na Kim +8 more
doaj +1 more source

