Results 11 to 20 of about 6,733 (253)

Magnetic resonance imaging of pure ovarian dysgerminoma: a series of eight cases

Cancer Imaging, 2021
Background Imaging findings have a prominent role in early and correct identification of ovarian dysgerminoma, the most common ovarian malignant germ cell tumor (OMGCT).
Laura Maria Cacioppa, Federico Crusco, Francesco Marchetti, Michele Duranti, Matteo Renzulli, Rita Golfieri   +5 more
doaj   +2 more sources

Ovarian Dysgerminoma in Pregnant Women with Viable Fetus: A Rare Case Report

Case Reports in Oncology, 2021
Dysgerminoma is an uncommon malignant tumor arising from the germ cells of the ovary. Its association with pregnancy is extremely rare, with a reported incidence of about 0.2–1 per 100,000 pregnancies.
Reda Youssef, Gamal Sayed Ahmed, Samir Alhyassat, Sanaa Badr, Ahmed Sabry, Samah Kohla   +5 more
doaj   +2 more sources

An aggressive systemic mastocytosis preceded by ovarian dysgerminoma

BMC Cancer, 2020
Background Aggressive systemic mastocytosis (ASM) is a rare malignant disease characterized by disordered mast cell accumulation in various organs. We here describe a female ASM patient with a previous history of ovarian dysgerminoma.
Makiko Tsutsumi, Hiroki Miura, Hidehito Inagaki, Yasuko Shinkai, Asuka Kato, Takema Kato, Susumu Hamada-Tsutsumi, Makito Tanaka, Kazuko Kudo, Tetsushi Yoshikawa, Hiroki Kurahashi   +10 more
doaj   +2 more sources

Dysgerminoma with Estrogen-Producing Functioning Stroma Presenting Precocious Puberty

Case Reports in Pathology, 2021
Dysgerminoma is a malignant ovarian germ cell tumor, and unlike sex-cord stromal tumors, endocrine manifestation is considered rare. Here, we report the first case of dysgerminoma presenting precocious puberty.
Shunsuke Nagase, Kanako Ogura, Karin Ashizawa, Nana Nakazawa-Tanaka, Masahiko Urao, Masaharu Fukunaga, Yuto Yamazaki, Hironobu Sasano, Toshiharu Matsumoto   +8 more
doaj   +2 more sources

Pure ovarian dysgerminoma in a postmenopausal patient: A case report and review of the management

Gynecologic Oncology Reports, 2022
Background: A pure ovarian dysgerminoma in a postmenopausal female is a rare phenomenon. Case: A 65-year-old female presented with a large pelvic mass. Following surgical debulking, the patient was diagnosed with FIGO Stage IIB ovarian dysgerminoma.
Jennifer Vaz, Alexandra Mulliken, Nivin Omar, Jessa Suhner, Bogna Brzezinska, Thomas Cotter, Patel Nikhil, Robert V. Higgins, Bunja Rungruang   +8 more
doaj   +2 more sources

Late Recurrence in Ovarian Dysgerminoma Presenting as a Primary Retroperitoneal Tumor: A Case Report and Review of the Literature

Case Reports in Pathology, 2020
Ovarian dysgerminoma is a rare type of germ cell tumor. The majority of patient relapses occur within 2 years of diagnosis. Here, we report the case of a 74-year-old woman with a history of ovarian dysgerminoma 39 years earlier.
Yuichiro Sato, Tohru Hayashi, Hidetaka Yamamoto, Ichiro Niina, Naoya Kuroki, Takeshi Iwamura, Junji Onishi   +6 more
doaj   +2 more sources

Dysgerminoma with a Somatic Exon 17 KIT Mutation and SHH Pathway Activation in a Girl with Turner Syndrome

Diagnostics, 2020
This article reports a case of a 7-year-old girl with Turner syndrome, treated with growth hormone (GH), who developed ovarian dysgerminoma. The patient karyotype was mosaic for chromosome Xq deletion: 46,X,del(X)(q22)/45,X.
Ada Gawrychowska, Ewa Iżycka-Świeszewska, Beata S. Lipska-Ziętkiewicz, Dominika Kuleszo, Joanna Bautembach-Minkowska, Marcin Łosin, Joanna Stefanowicz   +6 more
doaj   +2 more sources

Advanced Ovarian Dysgerminoma With Supraclavicular Lymph Node Metastasis and Peritoneal Carcinomatosis: A Rare Case Report. [PDF]

Clin Case Rep
ABSTRACT Ovarian dysgerminoma is a rare, highly chemo‐sensitive germ cell tumor usually presenting early. We report a FIGO stage IVB case with supraclavicular lymph node metastasis and peritoneal carcinomatosis in a 31‐year‐old woman. Diagnosis was based on classical histopathology.
Khaniya B, Shah S, Adhikari D, Acharya A, Poudel A, Gautam S.   +5 more
europepmc   +2 more sources

Advanced-Stage Gonadal Dysgerminoma in a Patient With a Previous Diagnosis of Familial Swyer Syndrome: A Very Rare Genetic Entity. [PDF]

Case Rep Med
Introduction Swyer syndrome is a genetic abnormality characterized by a 46,XY karyotype in a phenotypically female individual. Affected individuals typically have average or tall stature, unambiguous genitalia at birth, the presence of Müllerian structures, and bilateral streak gonads.
Oğlak SC, Söğütçü N, Akgöl S, Adıgüzel Ö, Ateş Eminoğlu HE, Güzel G, Balcı V, Acar E, Acar A, Bozan F.   +9 more
europepmc   +2 more sources

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T-Cell Exhaustion in Dysgerminoma. [PDF]

Cancer Sci
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Nakashima M, Iwasaki T, Katayama Y, Shimo M, Takigawa K, Shimada N, Matsushita M, Kuwamoto S, Sato S, Toya M, Miyawaki K, Akashi K, Kato K, Oda Y.   +13 more
europepmc   +2 more sources