Results 91 to 100 of about 5,696 (226)

A Prognostic Stratification Model for Ovarian Cancer Integrating the Tumor‐Associated Macrophages/Programmed Death‐Ligand 1 Axis

Organ Medicine, Volume 3, Issue 3, Page 148-156, September 2026.
Tumor‐associated macrophages (TAMs) drive ovarian cancer (OC) progression and immune escape mainly via programmed death‐ligand 1 (PD‐L1) upregulation. This study aimed to construct a risk stratification model integrating these two immune biomarkers for OC precision prognosis.
Li Liu, Chenya Zhuo, Tingting Zhao, Qiongshan Liu, Yun Liu, Jingran Du, Dandan Yan, Qiuxiao Tan, Hui Fei, Xiaohui Tian, Mengxiong Li   +10 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Çocukluk çağı disgerminom tedavi sonuçları

Genel Tıp Dergisi, 2021
Amaç: Over disgerminomu tanısı ile izlenen hastala­rın demografik ve klinik özellikleri ile tedavi yaklaşımlarını geriye dönük olarak incelemektir. Gereç ve Yöntem: XXXXXX Üniversitesi Tıp Fakültesi Çocuk Onkoloji Bilim Dalı’nda, 2006-2020 yılları ...
Buket Kara, Hilal Akbaş, İlhan Çiftçi, Yavuz Köksal   +3 more
doaj   +1 more source

Pregnancy‐Associated Small Cell Carcinoma of the Ovary, Hypercalcaemic Type Initially Misdiagnosed as Granulosa Cell Tumour: Diagnostic Pitfalls, Treatment Challenges, and Molecular Confirmation by Next‐Generation Sequencing

Cancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Small cell carcinoma of the ovary, hypercalcaemic type (SCCOHT), is an exceptionally rare and highly aggressive ovarian malignancy affecting predominantly young women. Its overlapping morphology with other poorly differentiated ovarian tumours and lack of specific early markers frequently lead to diagnostic delay.
Mahendra Kumar, Lopamundra Kakoti, Debabrata Barmon, Upasana Baruah, Dimpy Begum, P. S. Roy, Karthik Chandra Bassetty, Deepali Mittal, Bharati Seth   +8 more
wiley   +1 more source

Ovarian gonadoblastoma with dysgerminoma in a girl with 46,XX karyotype 17a-hydroxylase/17, 20-lyase deficiency: A case report and literature review

Frontiers in Endocrinology, 2022
17α−hydroxylase/17,20−lyase deficiency (17-OHD), caused by mutations in the gene of the cytochrome P450 family 17 subfamily A member 1 (CYP17A1), is a rare type of congenital adrenal hyperplasia (CAH), usually characterized by cortisol and sex steroid ...
Min Yin, Jiaxin Yang, Qinjie Tian, Xinyue Zhang   +3 more
doaj   +1 more source

'A bad ball - game'

South African Family Practice, 1986
No abstract available.
Roy Jobson
doaj   +1 more source

Diagnosis and Management of Dysgerminomas with a Brief Summary of Primitive Germ Cell Tumors

Diagnostics, 2022
Dysgerminoma represents a rare malignant tumor composed of germ cells, originally from the embryonic gonads. Regarding its incidence, we do not have precise data due to its rarity. Dysgerminoma occurs at a fertile age.
Melinda-Ildiko Mitranovici, Diana Maria Chiorean, Maria Cezara Mureșan, Corneliu-Florin Buicu, Raluca Moraru, Liviu Moraru, Titiana Cornelia Cotoi, Ovidiu Simion Cotoi, Havva Serap Toru, Adrian Apostol, Sabin Gligore Turdean, Claudiu Mărginean, Ion Petre, Ioan Emilian Oală, Zsuzsanna Simon-Szabo, Viviana Ivan, Lucian Pușcașiu   +16 more
doaj   +1 more source

Metastatic dysgerminoma in a young patient with 46 XY DSD: A rare case report

Gynecologic Oncology Reports, 2020
Highlights • A rare case of metastatic dysgerminoma in a young patient with 46XY DSD.• Incidence of DSD is 1:5000 with 90% of patients having 46XX chromosome and only 10% have 46 XY chromosome.• Individuals with an underlying DSD, especially with Y ...
Surekha S Thakur, S. C. Saha, P. Sikka, C. Das, K. Arpitha, U. Thakur   +5 more
semanticscholar   +1 more source

Synchronous ovarian dysgerminoma and metastatic breast carcinoma: A case report [PDF]

, 2020
Introduction: Synchronous dual malignancies are rare findings. A unique case report of first of its kind of synchronous ovarian dysgerminoma and metastatic infiltrating duct carcinoma of the breast is being reported.
Singh PK, Prasad SN, Aqueel M, Mishra MP, Raza MW   +4 more
core  

Bilateral Gonadoblastoma in a 12‐Year‐Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case of a 12‐year‐old patient who developed bilateral gonadoblastoma 4 years after treatment for Wilms tumor highlights the importance of rigorous, risk‐adapted long‐term surveillance and careful evaluation of incidental gonadal findings, even in asymptomatic patients.
Ahmed Quraish, Hasan Khouli, Yousef Daraghmeh, Sultan Mosleh, Samer Bustame   +4 more
wiley   +1 more source