Results 71 to 80 of about 5,696 (226)

Swyer syndrome (46, XY complete gonadal dysgenesis): A rare case of primary amenorrhea

Philippine Journal of Obstetrics and Gynecology, 2022
Swyer syndrome is a type of gonadal dysgenesis wherein a 46, XY karyotype presents with a female phenotype. It is a rare cause of disorder in sexual development that occurs in 1:100,000 births. Local studies are currently limited to few case reports. Sex-
Pamela Maria P. Mallari, Sherry L. Carlos-Navarro   +1 more
doaj   +1 more source

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T-Cell Exhaustion in Dysgerminoma. [PDF]

Cancer Sci
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Nakashima M, Iwasaki T, Katayama Y, Shimo M, Takigawa K, Shimada N, Matsushita M, Kuwamoto S, Sato S, Toya M, Miyawaki K, Akashi K, Kato K, Oda Y.   +13 more
europepmc   +2 more sources

Hypercalcemia associated with dysgerminoma and elevation of calcitriol: A case report and review of the literature

SAGE Open Medical Case Reports, 2022
We report on the case of a patient with dysgerminoma, a rare germ cell tumor, which showed hypercalcemia with an elevation of 1α,25-dihydroxycholecalciferol (calcitriol). A 27-year-old nulliparous woman presented with hypercalcemia during the examination
Natsuko Hara, Hirotsugu Suwanai, Hironori Abe, Fumiyoshi Yakou, Takuya Ishikawa, Munehiro Urayama, Takeshi Nagai, Toshitaka Nagao, Jumpei Shikuma, Takashi Miwa, Ryo Suzuki, Masato Odawara   +11 more
doaj   +1 more source

Histomorphological Spectrum of Gonadal and Extragonadal Germ Cell Tumours at a Tertiary Cancer Centre in Southern Rajasthan, India [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Germ Cell Tumours (GCT) are heterogenous tumours believed to arise from primordial germ cells. The GCT predominantly affects gonads (testis and ovary) and also involves extragonadal sites, characteristically locations along midline of ...
Tarang Patel, Swati Jindal, Swati Jindal, Aruna Panchariya   +3 more
doaj   +1 more source

Cutaneous Metastasis in a Previously Known Case of Ovarian Dysgerminoma: A Case Report

International Journal of Cancer Management, 2021
Introduction: Cutaneous metastasis is an uncommon manifestation that mostly occurs in patients with previous gastrointestinal or gynecological malignancies. Local recurrence usually can be seen in surgical incisions. Dysgerminomas are rare ovarian tumors
Farrokh Seilanian Toosi, M. Hasanzadeh, Mona Maftouh, Ahmadreza Tavassoli   +3 more
semanticscholar   +1 more source

A Rare Case of Ovarian Dysgerminoma with Torsion in Pregnancy [PDF]

Journal of Clinical and Diagnostic Research
Early identification of the clinical and imaging characteristics of ovarian dysgerminoma is crucial for prompt care of this rare malignant germ cell tumour, which primarily affects young women and adolescents.
Komal Rathod, Pratap Singh Parihar, Bharadwaj Saraswathula, Saburi Singhania, Yogita Rathod   +4 more
doaj   +1 more source

A clinical case of unilateral ovarian dysgerminoma and pyometra in a bitch [PDF]

Macedonian Veterinary Review, 2014
A clinical case of an 11-year-old bitch with unilateral ovarian dysgerminoma and pyometra is described. The owner reported purulent discharge from external genitalia, fastidious appetite and depression.
Anton Antonov, Ivan Fasulkov, Radostin Simeonov   +2 more
doaj   +1 more source

46, XY complete gonadal dysgenesis with pubertal virilisation due to dysgerminoma/gonadoblastoma

BMJ Case Reports, 2020
Complete gonadal dysgenesis (CGD) or Swyer syndrome is characterised by sexual infantilism in a phenotypic female with 46, XY karyotype. Patients with gonadal dysgenesis and Y-chromosome material are at a high risk of developing gonadoblastoma and ...
S. Alam, H. Boro, Alpesh Goyal, R. Khadgawat   +3 more
semanticscholar   +1 more source

Metastasis of ovarian dysgerminoma in a postmenopausal patient: a rare case report

Annals of Medicine and Surgery
Ovary dysgerminoma is one of the most good prognosis malignant tumor, which has a 5-year overall survival rate exceeding to 90%. Generally, the incidence of ovarian dysgerminoma (OD) is relatively low, accounting for ~0.6% of all ovarian tumors. Usually,
Ziren Feng, Xin-Ning Zhang, Pan Wang, Qinglan Hu, Jinduan Lin   +4 more
semanticscholar   +1 more source

Bilateral Gonadoblastoma With Dysgerminoma in a Phenotypically Normal Female With 46XX Karyotype: Report of a Rare Case and Literature Review

Cureus, 2020
Gonadoblastoma is a rare ovarian neoplasm which belongs to “germ cell-sex cord-stromal tumor” category. This tumor is frequently associated with invasive germ cell malignancy.
M. Raafey, M. Abdulwaasey, S. Fatima, Zeeshan Uddin, M. Tariq   +4 more
semanticscholar   +1 more source