Results 61 to 70 of about 3,154 (149)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

KIT Gene Mutation and Amplification in Dysgerminoma of the Ovary

, 2010
BACKGROUND: Dysgerminoma, the ovarian counterpart of seminoma, is the most common type of malignant ovarian germ cell tumor. The role of KIT mutation and amplification in the development of dysgerminoma is not currently established.
Roth L. M., Cheng L., Abdul Karim F. W., Zhang S., Morton M. J., Lopez Beltran A., Wang M., Zheng W., MONTIRONI, RODOLFO, Mingsheng Wang, Rodolfo Montironi, Fadi W. Abdul Karim, Liang Cheng, Michael J. Morton, Wenxin Zheng, Antonio Lopez-Beltran, Shaobo Zhang, Lawrence M. Roth   +17 more
core   +1 more source

Ovarian gonadoblastoma with dysgerminoma in a girl with 46,XX karyotype 17a-hydroxylase/17, 20-lyase deficiency: A case report and literature review

Frontiers in Endocrinology, 2022
17α−hydroxylase/17,20−lyase deficiency (17-OHD), caused by mutations in the gene of the cytochrome P450 family 17 subfamily A member 1 (CYP17A1), is a rare type of congenital adrenal hyperplasia (CAH), usually characterized by cortisol and sex steroid ...
Min Yin, Jiaxin Yang, Qinjie Tian, Xinyue Zhang   +3 more
doaj   +1 more source

Pregnancy‐Associated Small Cell Carcinoma of the Ovary, Hypercalcaemic Type Initially Misdiagnosed as Granulosa Cell Tumour: Diagnostic Pitfalls, Treatment Challenges, and Molecular Confirmation by Next‐Generation Sequencing

Cancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Small cell carcinoma of the ovary, hypercalcaemic type (SCCOHT), is an exceptionally rare and highly aggressive ovarian malignancy affecting predominantly young women. Its overlapping morphology with other poorly differentiated ovarian tumours and lack of specific early markers frequently lead to diagnostic delay.
Mahendra Kumar, Lopamundra Kakoti, Debabrata Barmon, Upasana Baruah, Dimpy Begum, P. S. Roy, Karthik Chandra Bassetty, Deepali Mittal, Bharati Seth   +8 more
wiley   +1 more source

Incidental finding of dysgerminoma in a full-term pregnancy: a case report [PDF]

, 2023
Ovarian tumors are reported in 1 of every 200 pregnancies. Dysgerminoma with pregnancy is extremely rare, with a reported incidence of about 0.2-1 per 100,000 pregnancies.
K., Nayana, Patil, Vaibhav, Isha A. Luniya   +2 more
core   +1 more source

Diagnosis and Management of Dysgerminomas with a Brief Summary of Primitive Germ Cell Tumors

Diagnostics, 2022
Dysgerminoma represents a rare malignant tumor composed of germ cells, originally from the embryonic gonads. Regarding its incidence, we do not have precise data due to its rarity. Dysgerminoma occurs at a fertile age.
Melinda-Ildiko Mitranovici, Diana Maria Chiorean, Maria Cezara Mureșan, Corneliu-Florin Buicu, Raluca Moraru, Liviu Moraru, Titiana Cornelia Cotoi, Ovidiu Simion Cotoi, Havva Serap Toru, Adrian Apostol, Sabin Gligore Turdean, Claudiu Mărginean, Ion Petre, Ioan Emilian Oală, Zsuzsanna Simon-Szabo, Viviana Ivan, Lucian Pușcașiu   +16 more
doaj   +1 more source

Chemotherapy of advanced dysgerminoma: trials of the Gynecologic Oncology Group.

, 1991
Between 1984 and 1989, 20 assessable patients with incompletely resected ovarian dysgerminoma were treated on two protocols of the Gynecologic Oncology Group (GOG). All patients received cisplatin, bleomycin, and either vinblastine or etoposide.
K D Hatch, S D Williams, J A Blessing, H D Homesley   +3 more
core   +1 more source

'A bad ball - game'

South African Family Practice, 1986
No abstract available.
Roy Jobson
doaj   +1 more source

Synchronous ovarian dysgerminoma and metastatic breast carcinoma: A case report [PDF]

, 2020
Introduction: Synchronous dual malignancies are rare findings. A unique case report of first of its kind of synchronous ovarian dysgerminoma and metastatic infiltrating duct carcinoma of the breast is being reported.
Singh PK, Prasad SN, Aqueel M, Mishra MP, Raza MW   +4 more
core  

Bilateral Gonadoblastoma in a 12‐Year‐Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case of a 12‐year‐old patient who developed bilateral gonadoblastoma 4 years after treatment for Wilms tumor highlights the importance of rigorous, risk‐adapted long‐term surveillance and careful evaluation of incidental gonadal findings, even in asymptomatic patients.
Ahmed Quraish, Hasan Khouli, Yousef Daraghmeh, Sultan Mosleh, Samer Bustame   +4 more
wiley   +1 more source