Results 61 to 70 of about 2,345 (167)

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

Dysgerminoma and granulosa cell tumor in a bitch

Brazilian Journal of Veterinary Pathology, 2016
Dysgerminoma and granulosa cell tumor are neoplasms of the ovary of domestic animals, originating from germ cells and sex-cords cells, respectively. These neoplasms generally occur unilaterally, and usually as a single neoplasm.
Ayisa R. Oliveira, Mayra C. Flecher, Flávia F. Jabour, Tayse D. Souza, Isabela Hardt, Fernanda T. Vieira, Alice C. Rassele, Gabriel C. Vicente, Flávia M. Machado   +8 more
doaj   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

Clinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri, Sushil Yewale, Hannah Hickingbotham, Cara Williams, Mohamed Shalaby, Julie Alderson, Julie Park   +6 more
wiley   +1 more source

Feasibility and Safety of Intraoperative Oocyte Retrieval in Patients With Ovarian Tumor: Results From the Japan Oncofertility Registry

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose To evaluate the clinical utility and safety of intraoperative oocyte retrieval (IOR) as a fertility preservation (FP) strategy for patients with ovarian tumors using data from the Japan Oncofertility Registry (JOFR). Methods This retrospective study analyzed data from 226 patients with ovarian tumors registered in the JOFR between ...
Futa Ito, Satoshi Kubota, Taro Yagi, Mizuho Akedo, Yuta Tsuji, Masahiko Takemura, Ken‐ichirou Morishige   +6 more
wiley   +1 more source

Ovarian Dysgerminoma with Metastases in Supraclavicular Lymph Nodes Diagnosed in a 16-year-old Girl: Clinical Case and Literature Review

Lietuvos Chirurgija, 2018
[full article, abstract in English; abstract in Lithuanian] Background Tumors of children reproductive system are rare, the most frequent among them is ovarian tumor.
Diana Maldžiūtė, Vilma Rukauskaitė, Kęstutis Trainavičius   +2 more
doaj   +1 more source

Dysgerminoma of the Left Ovary in a Patient with Balanced Translocation 46X, t(X:1) (q22;q21): A Case Report

International Medical Case Reports Journal, 2023
Koh Nagata, Takako Shimada, Chiaki Eishi, Masaki Nishi, Toru Murakami, Kazuaki Ohashi, Itsuki Kajimura, Kiyonori Miura Obstetrics and Gynecology, Nagasaki University Hospital, Nagasaki, JapanCorrespondence: Koh Nagata, Obstetrics and Gynecology, Nagasaki
Nagata K, Shimada T, Eishi C, Nishi M, Murakami T, Ohashi K, Kajimura I, Miura K   +7 more
doaj  

Canine ovarian gonadoblastoma with dysgerminoma overgrowth: a case study and literature review

Journal of Ovarian Research, 2019
Background Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome.
Ana R. Flores, João Lobo, Francisco Nunes, Alexandra Rêma, Paula Lopes, Luís Carvalho, Carla Bartosch, Irina Amorim, Fátima Gärtner   +8 more
doaj   +1 more source

Swyer Syndrome: Clinical Case of Gonadal Dysgenesis in a 15-year-old Girl

Педиатрическая фармакология
Swyer syndrome is a rare genetic disorder in which gonadal dysgenesis and karyotype 46, XY are observed. In the postnatal and prepubescent period, this disease has no clinical manifestations and is asymptomatic, which makes diagnosis difficult. The first
Irina V. Karachentsova, Elena V. Sibirskaya, Tatyana G. Dyadik, Mariia Yu. Chernysheva, Kristina A. Osmanova, Varvara M. Golubkova, Anna V. Arutunyan, Angelina A. Sysoeva   +7 more
doaj   +1 more source

Study of germ cell tumors of ovary and associated immunohistochemistry [PDF]

Journal of Clinical and Basic Research
Background: Females have a 6–7% lifetime risk of developing ovarian tumors. Ovarian cancer is often termed a “silent killer” due to its frequent diagnosis at advanced stages.
Devunoori Sagarika, Shafaq Baseer, Shilpa Karamchedu, Syed Ali Baqher Hussaini, Rasheed Fatima, Panala Rajya Laxmi, Sana Sultana   +6 more
doaj  

First-trimester ovarian dysgerminoma in pregnancy: a case report highlighting the value of expert ultrasound

Frontiers in Oncology
BackgroundMalignant germ cell tumors are rare ovarian malignancies, accounting for less than 5% of ovarian cancers. Dysgerminoma is the most common subtype but remains exceptionally rare during pregnancy, with an estimated incidence of 0.2–1 per 100,000 ...
Natālija Vedmedovska, Natālija Vedmedovska, Zanda Ākule, Arta Spridzāne, Androniks Mitiļdžans, Alise Vinogradova, Vija Batalauska, Sergejs Isajevs, Francesca Moro   +8 more
doaj   +1 more source