Results 31 to 40 of about 4,122 (198)

A 46,XY female DSD patient with bilateral gonadoblastoma, a novel SRY missense mutation combined with a WT1 KTS splice-site mutation [PDF]

, 2012
Patients with Disorders of Sex Development (DSD), especially those with gonadal dysgenesis and hypovirilization are at risk of developing malignant type II germ cell tumors/cancer (GCC) (seminoma/dysgerminoma and nonseminoma), with either carcinoma in ...
Alders, M. (Mariëlle), Bernard, P. (Pascal), Boer, S. (Suzan) de, Brüggenwirth, H.T. (Hennie), Drop, S.L.S. (Stenvert), Harley, V.R. (Vincent), Hersmus, R. (Remko), Looijenga, L.H.J. (Leendert), McElreavy, K. (Kenneth), Oosterhuis, J.W. (Wolter), Sreenivasan, R. (Rajini), Stoop, J.A. (Hans), White, S.J. (Stefan), Wolffenbuttel, K.P. (Katja), Zwan, Y.G. (Yvonne ) van der   +14 more
core   +1 more source

Laparoscopic approach for gonadectomy in pediatric patients with intersex disorders [PDF]

, 2016
The birth of a child with a disorder of sex development (DSD) prompts a long-term management strategy that involves a myriad of professionals working with the family.
Calvo, Andres, Caprio, Maria Grazia, ESCOLINO, MARIA, ESPOSITO, CIRO, Roberti, Agnese, SETTIMI, ALESSANDRO   +5 more
core   +1 more source

Prolonged Hypercalcemia Following Resection of Dysgerminoma: A Case Report

Obstetrics and Gynecology International, 2009
Background. Hypercalcemia is a rare but potentially dangerous complication of pediatric cancer. Of the dysgerminoma cases reported to date, associated hypercalcemia is corrected within 2–7 days of tumor resection. Case.
Abigail Wald, Sumana Narasimhan, Lucybeth Nieves-Arriba, Steven Waggoner   +3 more
doaj   +1 more source

Swyer syndrome (46XY pure gonadal dysgenesis) presenting with dysgerminoma

Archives of Medicine and Health Sciences, 2019
Dysgerminoma is the most common malignant germ cell tumor of the ovary. This malignancy can be associated with pure gonadal dysgenesis (Swyer syndrome), mixed gonadal dysgenesis, and partial gonadal dysgenesis. Dysgerminoma usually develops in phenotypic
M Banyameen Iqbal, Iqra Mushtaq, Tushar Kambale, Indranil Dey   +3 more
doaj   +1 more source

Hypercalcemia associated with dysgerminoma and elevation of calcitriol: A case report and review of the literature

SAGE Open Medical Case Reports, 2022
We report on the case of a patient with dysgerminoma, a rare germ cell tumor, which showed hypercalcemia with an elevation of 1α,25-dihydroxycholecalciferol (calcitriol). A 27-year-old nulliparous woman presented with hypercalcemia during the examination
Natsuko Hara, Hirotsugu Suwanai, Hironori Abe, Fumiyoshi Yakou, Takuya Ishikawa, Munehiro Urayama, Takeshi Nagai, Toshitaka Nagao, Jumpei Shikuma, Takashi Miwa, Ryo Suzuki, Masato Odawara   +11 more
doaj   +1 more source

Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers [PDF]

, 2007
Background Ovarian germ cell tumours (OGCTs) typically arise in young females and their pathogenesis remains poorly understood. We investigated the origin of malignant OGCTs and underlying molecular events in the development of the ...
Hoei-Hansen, Christina E, Kraggerud, Sigrid M, Abeler, Vera M, Kærn, Janne, Rajpert-De Meyts, Ewa, Lothe, Ragnhild A   +5 more
core   +1 more source

Malignant ovarian germ cell tumors in pediatric patients: The AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) study [PDF]

, 2017
Objective: Malignant ovarian germ cell tumors (MOGCT) carry an excellent prognosis, and the treatment aims to achieve results with the least possible treatment-related morbidity. The aim of this study was to assess the outcomes of pediatric patients with
Amsalem, Baranzelli, Billmire, Billmire, Billmire, Frazier, Gershenson, Gershenson, Gobel, Grimison, Hanna, Kaplan, Kollmansberger, Lhommé, Lo Curto, Lopes, Madenci, Mangili, Mangili, Mangili, Mann, Matei, Meisel, Murray, Olson, Palenzuela, Park, Parkinson, Pashankar, Patterson, Pectasides, Rescorla, Robison, Rogers, Schemper, Schenider, Solheim, Stoneham, Travis, Vicus, Zagamè   +40 more
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Dual malignancy in adolescence: A rare case report of metachronous papillary carcinoma of thyroid following dysgerminoma of ovary

Journal of Research in Medical Sciences, 2016
Dual malignancy is rare in adolescents. Dual malignancy with the second malignancy of thyroid is rare. No association has been reported between dysgerminoma of ovary and carcinoma thyroid in medical literature. Despite a thorough PubMed search (key words
Suvadip Chakrabarti, Sanjay M Desai, Dharmendra Y Mehta, Shreyas Somanath   +3 more
doaj   +1 more source

Uncommon Metastasis of Ovarian Dysgerminoma: A Case Report and Review of the Literature

Medicina, 2021
Ovarian malignant germ cell tumors (OMGCT) represent less than 10% of all ovarian tumors. Dysgerminoma is the most common malignant primitive germ cell tumor in young women, known for its curability and low propensity to invade and metastasize when ...
Mihaela Camelia Tîrnovanu, Irina Daniela Florea, Adina Tănase, Bogdan Florin Toma, Elena Cojocaru, Carmen Ungureanu, Ludmila Lozneanu   +6 more
doaj   +1 more source

A clinical case of unilateral ovarian dysgerminoma and pyometra in a bitch [PDF]

Macedonian Veterinary Review, 2014
A clinical case of an 11-year-old bitch with unilateral ovarian dysgerminoma and pyometra is described. The owner reported purulent discharge from external genitalia, fastidious appetite and depression.
Anton Antonov, Ivan Fasulkov, Radostin Simeonov   +2 more
doaj   +1 more source