Results 101 to 110 of about 17,345 (219)

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein.
Maria Rosario, Jan de Hoon, Flonza Isa, Kenneth Turner, Jing Li, Joel Kantrowitz, Samit Ganguly, Sasha Fraser, Zhongqing Will He, Hong Yan, Ana Gonzalez Ortiz, Lori Faria, Ingeborg Heirman, Alina Baum, Thomas D Norton, Yogesh Patel, Veronica Mas Casullo, John D Davis   +17 more
wiley   +1 more source

Myasthenia Gravis With Thymoma, Manifesting as AChR-Ab-Positive, Distinct Bulbar Palsy Accompanied by Dysgeusia: A Case Series and Review of Literature

Frontiers in Neurology, 2018
In this review, we summarized three cases of myasthenia gravis (MG) with taste disorder and describe their clinical features in detail. Three MG patients presented with significant bulbar palsy symptoms, high AChR-Ab titers, and negative MuSK-Ab, were ...
Kai Zhu, Kai Zhu, Jiaxin Chen, Jiaxin Chen, Jingjing Li, Jingjing Li, Haiyan Wang, Haiyan Wang, Xin Huang, Xin Huang, Yan Li, Huiyu Feng, Huiyu Feng   +12 more
doaj   +1 more source

Abstract P6-11-16: Dysgeusia, weight and eating habits changes in breast cancer patients undergoing chemotherapy: A prospective cohort study

, 2018
Background: Dysgeusia is a frequent side effect in breast cancer patients undergoing adjuvant chemotherapy. The effect of dysgeusia on changes in diet and patient weight has been poorly investigated.
G Schivardi, V Coccoli, S Bosio, A Zanini, EL Simoncini, R Pedersini, M Romelli, M Claps, M Guerra, L Vassalli, V Amoroso, F Rodella, A Berruti   +12 more
core   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, Volume 67, Issue 10, Page 5075-5125, October 2026.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Antimicrobial Resistance‐Stratified Efficacy of Vonoprazan, Clarithromycin, and Metronidazole Therapy for Helicobacter pylori Eradication in Penicillin‐Allergic Patients: A Single‐Arm Prospective Interventional Study

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Choosing an effective Helicobacter pylori eradication regimen for patients with penicillin allergy remains a clinical challenge. Although vonoprazan‐based regimens yield excellent outcomes in standard populations, we still lack sufficient evidence regarding penicillin‐allergic patients.
Soichiro Sue, Ryosuke Ikeda, Aya Ikeda, Hiroki Sato, Yoshihiro Goda, Hiroaki Kaneko, Kuniyasu Irie, Shin Maeda   +7 more
wiley   +1 more source

Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial

Journal of Research in Medical Sciences, 2013
Background: Taste abnormalities are common among cancer patients after starting radiotherapy or chemotherapy. Considering the role of zinc and reports on its beneficial effects in taste perception, we evaluated the preventive effects of zinc sulfate on ...
Nadia Najafizade, Simin Hemati, Abbas Gookizade, Nezameddin Berjis, Mostafa Hashemi, Soheil Vejdani, Alireza Ghannadi, Armindokht Shahsanaee, Nafise Arbab   +8 more
doaj  

Evaluation of taste score and fungiform papillae quantification using digital image analysis in COVID-19 patients with smell and taste dysfunction

Dental Research Journal
Background: The COVID-19 pandemic which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a major global health crisis in recent years.
Vidya Chikkarahalli Srikantaiah, Anil Somashekara Bilimale, Vidya Gowdappa Doddawad, Srinath Kenkere Marulaiah, Hathur Basavana Gowdappa, Ranjitha Shankaregowda, Basavegowda Madhu, Amulya Manohar Thotambailu, Raghu Ram Achar   +8 more
doaj   +1 more source

Traumatic Dysgeusia, an Unusual Complication of Facial Trauma: A Case Report

, 2016
The chemical senses of taste and smell are important to human life, because they play an important role in detecting potential environmental hazards.
Bonardi, João Paulo [UNESP], Stabile, Glaykon Alex Vitti, da Costa, Fernanda Herrera, Bonardi, João Paulo, Pereira-Stabile, Cecilia Luiz   +4 more
core   +1 more source

The experience of dysgeusia in allogeneic haematopoietic cell transplantation survivors: a qualitative study

, 2019
Taste disorders are one of the most common side effects of treatment in oncology patients and often occur after allogeneic haematopoietic cell transplantation (allo-HCT).
Bomben, Davide, Ghirotto, Luca, Bin, Alessandra, Bulfone, Teresa, Venturini, Margherita, Bressan, Valentina   +5 more
core   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

British Journal of Haematology, Volume 209, Issue 4, Page 1450-1468, October 2026.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo, Maria Georgiou, Donal P. McLornan, Claire N. Harrison   +3 more
wiley   +1 more source