Results 71 to 80 of about 16,917 (221)

Real‐world outcomes of zavegepant use in a tertiary care setting using the Migraine Treatment Optimization Questionnaire‐5

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The introduction of calcitonin gene‐related peptide antagonists has transformed migraine care. Zavegepant, a third‐generation intranasal gepant, offers a nonoral treatment option for acute migraine. Although clinical trials support its efficacy and safety, real‐world data are limited.
Eric Dunn, Bradley Ong, Harpreet Kaur, Roman Popov, Claire Sonneborn, Aarushi Suneja   +5 more
wiley   +1 more source

Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial

Trials, 2020
Objectives To assess the efficacy of local intranasal treatment with budesonide (nasal irrigation), in addition to olfactory rehabilitation, in the management of loss of smell in COVID-19 patients without signs of severity and with persistent hyposmia 30
Mary Daval, Alain Corré, Clement Palpacuer, Juliette Housset, Guillaume Poillon, Michael Eliezer, Benjamin Verillaud, Dorsaf Slama, Denis Ayache, Philippe Herman, Clement Jourdaine, Camille Hervé, Wissame El Bakkouri, Dominique Salmon, Charlotte Hautefort   +14 more
doaj   +1 more source

Epidermal necrolysis sequelae: A cohort study on prevalence and risk factors

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Long‐term sequelae after epidermal necrolysis are frequent, multiple and often severe. Cutaneous, ocular and psychological complications are more frequent, with significant socioeconomic impact. Cluster analysis identifies distinct patient profiles, highlighting the need for personalized multidisciplinary follow‐up.
Thanh Vy Nguyen, Thomas Bettuzzi, Karim Zaghbib, Julie Gueudry, Audrey Colin, Kmar Bel Hareth, Narimane Terkmane, Emilie Sbidian, Nicolas de Prost, Saskia Ingen‐Housz‐Oro   +9 more
wiley   +1 more source

Safety, Tolerability, and Pharmacokinetics of Filapixant, a Highly Selective P2X3 Receptor Antagonist, in an Ascending-Single-Dose First-in-Human Study

Pharmaceuticals
Background/Objectives: P2X3 receptor antagonists have been suggested as a potential treatment for urogenital, respiratory and pain conditions. This first-in-human (FiH) study evaluated filapixant, a new P2X3 receptor antagonist with high receptor ...
Klaus Francke, Sybille Baumann, Isabella Gashaw, Stefan Klein, Beate Rohde, Oliver Zolk, Oliver M. Fischer, Christian Friedrich   +7 more
doaj   +1 more source

[Dysgeusias].

Revista de gastroenterologia de Mexico, 1979
This is a review of multiple pathologic conditions associated with altered taste perception and identification. We stated the steps and the molecular basis of this sense. This paper includes two cases that exemplify two distinct types of dysgeusia; case, 1 a 48 year old man who had clinical manifestations of hypogeusia and dysgeusia for one year ...
J A, Tamayo y Orozco, A A, Cario
openaire   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

Journal of Oral Rehabilitation, EarlyView.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher   +3 more
wiley   +1 more source

The Prevalence of Anosmia and Dysgeusia in Relation to Sex, Age, and Smoking during COVID-19 Second Wave: A Retrospective Analysis of a Sample of Patients in Hilla City

Medical Journal of Babylon
Background: Olfactory and gustatory dysfunction are among the significant symptoms of COVID-19 infection that show diversity in prevalence and recovery with a great impact on patients’ life. Objectives: This study aimed to evaluate the impact of age, sex,
Maytham Riad Ali, Malath Azeez Al-Saadi
doaj   +1 more source

Miraculin Can Contribute to a Reduction in Inflammatory Biomarkers and Cachexia in Malnourished Patients with Cancer and Taste Disorders

Pharmaceuticals
Background: In 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths. The number of new cancer cases is expected to rise to over 35 million by 2050, marking a 75% increase from 2022 levels.
Ana Isabel Álvarez-Mercado, Bricia López-Plaza, Julio Plaza-Diaz, Lucía Arcos-Castellanos, Francisco Javier Ruiz-Ojeda, Marco Brandimonte-Hernández, Jaime Feliú-Batlle, Thomas Hummel, Samara Palma-Milla, Ángel Gil   +9 more
doaj   +1 more source

Comparative Study of Clinical Characteristics According to Pain Distribution in Lingual Burning Mouth Syndrome

Journal of Oral Rehabilitation, EarlyView.
Tongue pain mapping in 256 patients with lingual burning mouth syndrome identified distinct clinical phenotypes according to pain distribution. Wider pain areas were associated with higher pain intensity and poorer oral health‐related quality of life, supporting individualised assessment and targeted management.
Yoohyun Sim, Na‐Yeon Ha, Seok‐Jae Ko, Jae‐Woo Park, Jinsung Kim   +4 more
wiley   +1 more source

Is Capsaicin Effective in Relieving the Symptoms of Burning Mouth Syndrome? A Systematic Review

Journal of Oral Rehabilitation, EarlyView.
The capsaicin, administered topically or systemically, reduces pain symptoms in patients with Burning Mouth Syndrome (BMS). However, despite consistent clinical improvement, the current evidence is limited and of low certainty, highlighting the need for well‐designed studies to confirm its effectiveness. ABSTRACT Background Burning Mouth Syndrome (BMS)
Ana Paula de Andrade Silva, Ian Wesley Rocha dos Santos, Zuleni Alexandre da Silva, Deborah Ribeiro Frazão, José Mário Matos‐Sousa, Wallacy Watson Pereira Melo, Rafael Rodrigues Lima, Renata Duarte de Souza‐Rodrigues   +7 more
wiley   +1 more source