Results 41 to 50 of about 4,338 (156)
Journal of Clinical Periodontology, EarlyView.ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
Dyskeratosis Congenita and Corneal Refractive Surgery
Ophthalmology and Therapy, 2019 Dyskeratosis congenita is a syndrome of bone marrow failure secondary to unstable telomeres. It is characterized by a range of mucocutaneous diseases. Due to premature telomere shortening, these patients have limbal stem cell deficiency leading to poor ...
Madeline B. Heiland +4 more
doaj +1 more source
A Retrospective Analysis of the Diagnostic Accuracy in Diagnosing OPMD and Benign Oral Lesions
Oral Diseases, EarlyView.ABSTRACT Objective The clinical suspicion of a neoplastic lesion necessitates prompt diagnostic assessment through oral biopsy. However, the failure to accurately recognize an oral potentially malignant disorder (OPMD) or the misdiagnosis of a benign lesion can lead to diagnostic delays with significant impact on the patient's health.
Griselda Pedroso Acosta +6 more
wiley +1 more source
Oral Lichenoid Lesions in Patients With Dyskeratosis Congenita: A Retrospective Case Series
Oral Diseases, EarlyView.ABSTRACT Background Dyskeratosis congenita (DKC) is a rare inherited multisystem disorder primarily affecting the mucocutaneous and hematopoietic systems. Classically, it presents with the ectodermal triad of reticulate skin pigmentation, nail dystrophy, and oral leukoplakia.
Yehuda Zadik +9 more
wiley +1 more source
Zinser–Engmann–Cole syndrome: Two case report
Indian Journal of Paediatric Dermatology, 2019 We report two cases of dyskeratosis congenita. Case 1: An 11-year-old male child presented to us with severe anemia and pancytopenia resulting in cardiac failure, in addition to the classical clinical triad including skin atrophy with mottled ...
Bangaru Hanumaiah +2 more
doaj +1 more source
LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation
Aging Cell, Volume 25, Issue 9, September 2026.We present LivAge, an online aging clock that estimates murine transcriptomic age from hepatic RNA‐seq data. Externally validated, it detects accelerated aging in progeroid models and quantifies the effect of geroprotective interventions, providing an accurate, accessible, and ready‐to‐use tool for aging research.
Víctor Celemín‐Capaldi +6 more
wiley +1 more source
BMC Medical Genetics, 2018 Background Dyskeratosis congenita (DC) is an inherited telomeropathy characterized by mucocutaneous dysplasia, bone marrow failure, cancer predisposition, and other somatic abnormalities. Cells from patients with DC exhibit short telomere.
Yingqi Shao +5 more
doaj +1 more source
Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. [PDF]
PLoS ONE, 2014 The predominant X-linked form of Dyskeratosis congenita results from mutations in DKC1, which encodes dyskerin, a protein required for ribosomal RNA modification that is also a component of the telomerase complex. We have previously found that expression
Cristina Manguan-Garcia +10 more
doaj +1 more source
The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics
Clinical Genetics, Volume 110, Issue 3, Page 389-401, September 2026.The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree +18 more
wiley +1 more source