Results 141 to 150 of about 16,889 (275)
Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease
Neuroprotection, EarlyView.In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong +3 more
wiley +1 more source
Phytotherapy Research, EarlyView.Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández +5 more
wiley +1 more source
Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease
VIEW, EarlyView.This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin +5 more
wiley +1 more source
Phenobarbital induced buccolingual dyskinesia in oral apraxia
, 1988 A young woman with oral apraxia and a well-defined brain lesion on CT scan developed buccolingual dyskinesia lasting 40 days after low phenobarbital (PB) doses.
Piras, Maria Rita +6 more
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Cell Proliferation, EarlyView.CSTB deficient EPM1 iPS cells manifest increased lysosomal activity and oxidative stress, which lead to DNA damage, cell cycle defects and increased apoptosis. As a protective response, metabolism is suppressed. Image created by BioRender https://BioRender.com/t44oc6h.
Shekhar Singh +4 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.The first Australian guidance document on the assessment and management of idiopathic gastroparesis (IGP) reconceptualises IGP as a sensorimotor disorder. It proposes a novel multidisciplinary treatment algorithm and 20 high‐consensus recommendations, addressing common overlapping disorders, and providing clear guidance on associated disordered eating ...
Trina Kellar +11 more
wiley +1 more source
Rethinking Mitochondrial Parkinson's Disease in the α‐Synuclein Seed Amplification Assays Era
Movement Disorders, EarlyView.
Marco Percetti +3 more
wiley +1 more source
Adverse outcomes between VMAT2 and anticholinergics in tardive dyskinesia: A target trial emulation
Psychiatry and Clinical Neurosciences, EarlyView.Aim Vesicular monoamine transporter 2 (VMAT2) inhibitors have been approved for the treatment of tardive dyskinesia (TD), whereas anticholinergic agents are still widely used for this condition. This study aimed to compare the risk of major clinical adverse outcomes among patients with TD treated with VMAT2 inhibitors versus anticholinergic agents ...
Tien‐Wei Hsu +13 more
wiley +1 more source
Randomized clinical trial of topiramate for levodopa-induced dyskinesia in Parkinson\u27s disease
Background: The antiepileptic drug topiramate reduces levodopa-induced dyskinesia without exacerbating parkinsonism in animal models. We report a randomized, double-blind, placebo-controlled crossover trial in patients with Parkinson\u27s disease and ...
Kass-Iliyya L +5 more
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