Results 21 to 30 of about 349,122 (350)

Circulating PCSK9 and cardiovascular events in FH patients with standard lipid-lowering therapy

Journal of Translational Medicine, 2019
Background Proprotein convertase subtilisin/kexin 9 (PCSK9) has been proposed as a novel target for coronary artery disease (CAD). Familial hypercholesterolemia (FH) is characterized by high prevalence of CAD and major cardiovascular events (MACEs ...
Ye-Xuan Cao, Jing-Lu Jin, Di Sun, Hui-Hui Liu, Yuan-Lin Guo, Na-Qiong Wu, Rui-Xia Xu, Cheng-Gang Zhu, Qian Dong, Jing Sun, Jian-Jun Li   +10 more
doaj   +1 more source

Occupational Physical Activity and Cardiovascular Risk Factors Profile in the Adult Population of the Southern Cone of Latin America: Results From the CESCAS I Study [PDF]

, 2018
OBJECTIVE: We explore the association between occupational physical activity (OPA) and cardiovascular risk factors in four cities of the Southern Cone. METHODS: Robust multivariable linear regression models were used to examine the associations. RESULTS:
Elorriaga, Natalia, Gutierrez, Laura, Irazola, Vilma, Melendi, Santiago Ezequiel, Poggio, Rosana   +4 more
core   +1 more source

Comparison of statin plus ezetimibe with double-dose statin on lipid profiles and inflammation markers

Lipids in Health and Disease, 2018
Background Achievement of low-density lipoprotein cholesterol (LDL-C) goal is the most important for the patients with atherosclerotic cardiovascular diseases (ASCVD) who received lipid-lowering therapy.
Na-Qiong Wu, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Xi Zhao, Di Sun, Jing Sun, Rui-Xia Xu, Geng Liu, Qian Dong, Jian-Jun Li   +10 more
doaj   +1 more source

PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]

, 2019
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F., Burghaus, Jana, Cao Ho, Thanh, Jürgensen, Lonny, Kamuf-Schenk, Verena, Katus, Hugo A., Kiper, Leon, Krull, Alexandros, Riechert, Eva, Schecker, Johannes, Stangl, Karl, Stangl, Verena, Völkers, Mirko, Wöltje, Kerstin, Zhang, Kevin Sun   +14 more
core   +1 more source

Novel and traditional lipid-related biomarkers and their combinations in predicting coronary severity

Scientific Reports, 2017
We investigated simultaneously traditional and novel lipid indices, alone or in combination, in predicting coronary severity assessed by Gensini score (GS) in 1605 non-lipid-lowering-drug-treated patients undergoing coronary angiography.
Sha Li, Yuan-Lin Guo, Xi Zhao, Yan Zhang, Cheng-Gang Zhu, Na-Qiong Wu, Rui-Xia Xu, Ping Qing, Ying Gao, Xiao-Lin Li, Jing Sun, Geng Liu, Qian Dong, Jian-Jun Li   +13 more
doaj   +1 more source

Impact of free fatty acids on prognosis in coronary artery disease patients under different glucose metabolism status

Cardiovascular Diabetology, 2019
Background The aim of the present study is to examine the effects of free fatty acids (FFAs) on major cardiovascular events (MACEs) in patients with stable coronary artery disease (CAD) and different glucose metabolism status.
Jing-Lu Jin, Ye-Xuan Cao, Hui-Hui Liu, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Ying Gao, Jing Sun, Qian Dong, Jian-Jun Li   +11 more
doaj   +1 more source

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study. [PDF]

, 2017
Background: Published evidence indicates that individual use of metformin and statin is associated with reduced cancer mortality. However, their differential and joint effects on pancreatic cancer survival are inconclusive.Methods: We identified a large ...
Demissie, Kitaw, E, Jian-Yu, Graber, Judith M., Lin, Yong, Lu, Shou-En, Lu-Yao, Grace, Petersen, Gloria M., Rotter, David, Tan, Xiang-Lin, Zhang, Lanjing   +9 more
core   +2 more sources

Association of plasma free fatty acids levels with the presence and severity of coronary and carotid atherosclerotic plaque in patients with type 2 diabetes mellitus

BMC Endocrine Disorders, 2020
Background Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful marker for predicting ASCVD.
Ming-Hua Zhang, Ye-Xuan Cao, Li-Guo Wu, Na Guo, Bing-Jie Hou, Li-Jing Sun, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong, Jian-Jun Li   +9 more
doaj   +1 more source

Long-term prognosis for individuals with hypertension undergoing coronary artery calcium scoring [PDF]

, 2015
To examine the performance of coronary artery calcification (CAC) for stratifying long-term risk of death in asymptomatic hypertensive ...
Callister, Tracy Q, Chang, Hyuk Jae, Cho, Iksung, Giambrone, Ashley E, Gransar, Heidi, Heo, Ran, Kalra, Dan K, Lin, Fay Y, Min, James K., Schulman Marcus, Joshua, Sciarretta, Sebastiano, Shaw, Leslee J, Truong, Quynh A, Valenti, Valentina, Ó. Hartaigh, Bríain   +14 more
core   +1 more source

Genetic basis of index patients with familial hypercholesterolemia in Chinese population: mutation spectrum and genotype-phenotype correlation

Lipids in Health and Disease, 2018
Background Although there have been many reports in the genetics of familial hypercholesterolemia (FH) worldwide, studies in regard of Chinese population are lacking.
Di Sun, Bing-Yang Zhou, Sha Li, Ning-Ling Sun, Qi Hua, Shu-Lin Wu, Yun-Shan Cao, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Ying Gao, Chuan-Jue Cui, Geng Liu, Jian-Jun Li   +13 more
doaj   +1 more source