Results 11 to 20 of about 339,685 (297)

Atherogenic dyslipidemia

Indian Journal of Endocrinology and Metabolism, 2013
Atherogenic dyslipidemia (AD) refers to elevated levels of triglycerides (TG) and small-dense low-density lipoprotein and low levels of high-density lipoprotein cholesterol (HDL-C).
C N Manjunath, Jayesh R Rawal, Paurus Mehelli Irani, K Madhu   +3 more
doaj   +3 more sources

Diabetes Dyslipidemia [PDF]

Diabetes Therapy, 2016
Diabetes mellitus is associated with a considerably increased risk of premature atherosclerotic cardiovascular disease. Intensive glycemic control has essentially failed to significantly improve cardiovascular outcomes in clinical trials. Dyslipidemia is common in diabetes and there is strong evidence that cholesterol lowering improves cardiovascular ...
Schofield, Jonathan D, Liu, Yifen, Rao-Balakrishna, Prasanna, Malik, Rayaz A, Soran, Handrean   +4 more
openaire   +2 more sources

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Editorial: Secondary Dyslipidemias [PDF]

The Open Cardiovascular Medicine Journal, 2011
The term “secondary dyslipidemias” is used to describe the quantitative and/or qualitative alterations in lipoprotein metabolism that complicate the course of other medical disorders. Although the precise prevalence of secondary dyslipidemias has not been determined, the increasing incidence of the conditions that predispose to their development (such ...
Elisaf, M. S., Tsimihodimos, V.
openaire   +3 more sources

Detecting Familial hypercholesterolemia in children and adolescents: potential and challenges

Italian Journal of Pediatrics, 2022
Background It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.
Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano, Cristina Pederiva   +5 more
doaj   +1 more source

Relation between cost of drug treatment and body mass index in people with type 2 diabetes in Latin America [PDF]

, 2017
Aims Despite the frequent association of obesity with type 2 diabetes (T2D), the effect of the former on the cost of drug treatment of the latest has not been specifically addressed.
Enzo Rucci, Jorge Federico Elgart, Juan Jose Gagliardino, Lorena Gonzalez, Mariana Prestes, null null   +5 more
core   +2 more sources

Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

Journal of Translational Medicine, 2018
Background Patients with monogenic familial hypercholesterolemia (FH) have high risk for coronary artery disease (CAD). A recent FH Expert Panel suggested that FH was underdiagnosed and undertreated which needs early diagnosis.
Ye-Xuan Cao, Na-Qiong Wu, Di Sun, Hui-Hui Liu, Jing-Lu Jin, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Qiu-Ting Dong, Geng Liu, Qian Dong, Jian-Jun Li   +12 more
doaj   +1 more source

Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia [PDF]

, 2017
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab substantially reduce low‐density lipoprotein cholesterol (LDL‐C) when added to statin therapy in patients who need additional LDL‐C reduction ...
Bray, Sarah, Bridges, Ian, Cheng, Lung-I, Dent, Ricardo, Deshpande, Sohan, Forbes, Carol A., Gandra, Shravanthi R., Kleijnen, Jos, Ross, Janine, Sattar, Naveed, Stroes, Erik S.G., Toth, Peter P., Worth, Gavin M., Worthy, Gillian   +13 more
core   +1 more source

Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism

Cardiovascular Diabetology, 2018
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), a major regulator of cholesterol homeostasis, is associated with glucose metabolism. Liraglutide, a glucagon-like peptide-1 receptor agonist, can increase insulin secretion in a glucose ...
Sheng-Hua Yang, Rui-Xia Xu, Chuan-Jue Cui, Yin Wang, Ying Du, Zhi-Guo Chen, Yu-Hong Yao, Chun-Yan Ma, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Jing Sun, Bu-Xing Chen, Jian-Jun Li   +13 more
doaj   +1 more source

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study. [PDF]

, 2017
Background: Published evidence indicates that individual use of metformin and statin is associated with reduced cancer mortality. However, their differential and joint effects on pancreatic cancer survival are inconclusive.Methods: We identified a large ...
Demissie, Kitaw, E, Jian-Yu, Graber, Judith M., Lin, Yong, Lu, Shou-En, Lu-Yao, Grace, Petersen, Gloria M., Rotter, David, Tan, Xiang-Lin, Zhang, Lanjing   +9 more
core   +2 more sources