Results 21 to 30 of about 249,813 (313)

Update on dyslipidemia in hypothyroidism: the mechanism of dyslipidemia in hypothyroidism [PDF]

open access: yesEndocrine Connections, 2022
Hypothyroidism is often associated with elevated serum levels of total cholesterol, LDL-C and triglycerides. Thyroid hormone (TH) affects the production, clearance and transformation of cholesterol, but current research shows that thyroid-stimulating hormone (TSH) also participates in lipid metabolism independently of TH.
Huixing Liu, Daoquan Peng
openaire   +2 more sources

Circulating PCSK9 and cardiovascular events in FH patients with standard lipid-lowering therapy

open access: yesJournal of Translational Medicine, 2019
Background Proprotein convertase subtilisin/kexin 9 (PCSK9) has been proposed as a novel target for coronary artery disease (CAD). Familial hypercholesterolemia (FH) is characterized by high prevalence of CAD and major cardiovascular events (MACEs ...
Ye-Xuan Cao   +10 more
doaj   +1 more source

Novel and traditional lipid-related biomarkers and their combinations in predicting coronary severity

open access: yesScientific Reports, 2017
We investigated simultaneously traditional and novel lipid indices, alone or in combination, in predicting coronary severity assessed by Gensini score (GS) in 1605 non-lipid-lowering-drug-treated patients undergoing coronary angiography.
Sha Li   +13 more
doaj   +1 more source

Comparison of statin plus ezetimibe with double-dose statin on lipid profiles and inflammation markers

open access: yesLipids in Health and Disease, 2018
Background Achievement of low-density lipoprotein cholesterol (LDL-C) goal is the most important for the patients with atherosclerotic cardiovascular diseases (ASCVD) who received lipid-lowering therapy.
Na-Qiong Wu   +10 more
doaj   +1 more source

Impact of free fatty acids on prognosis in coronary artery disease patients under different glucose metabolism status

open access: yesCardiovascular Diabetology, 2019
Background The aim of the present study is to examine the effects of free fatty acids (FFAs) on major cardiovascular events (MACEs) in patients with stable coronary artery disease (CAD) and different glucose metabolism status.
Jing-Lu Jin   +11 more
doaj   +1 more source

Treatment of dyslipidemia [PDF]

open access: yesF1000Prime Reports, 2014
Atherosclerotic cardiovascular disease (including coronary heart disease, stroke and peripheral arterial disease) is the leading cause of death globally. Abnormal blood lipids (dyslipidemia), smoking, and high blood pressure are responsible for more than 75% of cases.
Tonkin, Andrew, Byrnes, Allison
openaire   +2 more sources

Association of plasma free fatty acids levels with the presence and severity of coronary and carotid atherosclerotic plaque in patients with type 2 diabetes mellitus

open access: yesBMC Endocrine Disorders, 2020
Background Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful marker for predicting ASCVD.
Ming-Hua Zhang   +9 more
doaj   +1 more source

Genetics of Dyslipidemia

open access: yesArquivos Brasileiros de Cardiologia, 2016
Lipoproteins constitute a set of proteins and lipids, organized to facilitate the transport of lipids through blood plasma. Elevated or decreased levels of these lipoproteins may be related to genetic alterations in 40% to 60% of cases.1 This fact explains why it is common to find lipid abnormalities in several members of the same family.
GarcĂ­a-Giustiniani, Diego   +1 more
openaire   +4 more sources

Genetic basis of index patients with familial hypercholesterolemia in Chinese population: mutation spectrum and genotype-phenotype correlation

open access: yesLipids in Health and Disease, 2018
Background Although there have been many reports in the genetics of familial hypercholesterolemia (FH) worldwide, studies in regard of Chinese population are lacking.
Di Sun   +13 more
doaj   +1 more source

Prevalence of Dyslipidemia and Its Influencing Factors among Elderly Community Residents [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Dyslipidemia is the most important and causal independent risk factor for atherosclerotic cardiovascular disease (ASCVD) . The prevalence of dyslipidemia in elderly residents in Guangdong Province is high, and it is urgent to analyze the ...
HUANG Qixian, WEN Yanting, HUANG Jun, LI Weibin, XU Yongneng, LIN Xiayi, WANG Haoxiang, WENG Fan, YANG Lianping
doaj   +1 more source

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