Results 21 to 30 of about 267,865 (313)

Beneficial impact of epigallocatechingallate on LDL-C through PCSK9/LDLR pathway by blocking HNF1α and activating FoxO3a

Journal of Translational Medicine, 2020
Background Green tea drinking has been proven to lower lipid and exert cardiovascular protection, while the potential mechanism has not been fully determined.
Chuan-Jue Cui, Jing-Lu Jin, Lin-Na Guo, Jing Sun, Na-Qiong Wu, Yuan-Lin Guo, Geng Liu, Qian Dong, Jian-Jun Li   +8 more
doaj   +1 more source

Statin-related Lichenoid Dermatosis: An Uncommon Adverse Reaction to a Common Treatment

European Journal of Case Reports in Internal Medicine, 2018
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are generally safe and well-tolerated drugs that are extensively used for the primary and secondary prevention of atherosclerotic cardiovascular events.
Zsófia Vesza, Catarina Pires, Pedro Marques da Silva   +2 more
doaj   +1 more source

ANALYSIS OF THE EFFECT OF CURCUMA LONGA ETHANOL EXTRACT AS ANTI-DYSLIPIDEMIA IN MALE WISTAR RATS [PDF]

, 2023
: Dyslipidemia is a lipid metabolism disorder characterized by increased or decreased lipid fractions in plasma. It is a risk factor for diseases still an essential problem in Indonesia, such as coronary heart disease (CHD).
Wang Rui
core   +1 more source

Outcomes of Dyslipidemia Screening Program in School-aged Children

, 2021
Aim:Screening of dyslipidemia in childhood has been controversial. While some guidelines recommend screening for dyslipidemia in children, others emphasize that there is insufficient evidence for screening for dyslipidemia in those less than 20 years of ...
Sipil Topçu, Baris, Buket, Engin Köse, Kose, Melis, Matur, Bo, Kose, Engin, Topcu, Sipil, Melis Köse, Behzat Özkan, Ozkan, Behzat, Buket Barış, Büşra Matur   +11 more
core   +1 more source

Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

Journal of Translational Medicine, 2018
Background Patients with monogenic familial hypercholesterolemia (FH) have high risk for coronary artery disease (CAD). A recent FH Expert Panel suggested that FH was underdiagnosed and undertreated which needs early diagnosis.
Ye-Xuan Cao, Na-Qiong Wu, Di Sun, Hui-Hui Liu, Jing-Lu Jin, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Qiu-Ting Dong, Geng Liu, Qian Dong, Jian-Jun Li   +12 more
doaj   +1 more source

Detecting Familial hypercholesterolemia in children and adolescents: potential and challenges

Italian Journal of Pediatrics, 2022
Background It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.
Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano, Cristina Pederiva   +5 more
doaj   +1 more source

Dyslipidemia [PDF]

, 2012
Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases.

core   +2 more sources

Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism

Cardiovascular Diabetology, 2018
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), a major regulator of cholesterol homeostasis, is associated with glucose metabolism. Liraglutide, a glucagon-like peptide-1 receptor agonist, can increase insulin secretion in a glucose ...
Sheng-Hua Yang, Rui-Xia Xu, Chuan-Jue Cui, Yin Wang, Ying Du, Zhi-Guo Chen, Yu-Hong Yao, Chun-Yan Ma, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Jing Sun, Bu-Xing Chen, Jian-Jun Li   +13 more
doaj   +1 more source

Free fatty acids and cardiovascular outcome: a Chinese cohort study on stable coronary artery disease

Nutrition & Metabolism, 2017
Background Studies have revealed that plasma level of free fatty acids (FFAs) is related to cardiovascular disease. However, the role of FFAs in clinical outcomes of stable coronary artery disease (SCAD) has been less evaluated.
Hui-Wen Zhang, Xi Zhao, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Jing Sun, Geng Liu, Qian Dong, Jian-Jun Li   +8 more
doaj   +1 more source

Oral Porphyromonas gingivalis and Fusobacterium nucleatum Abundance in Subjects in Primary and Secondary Cardiovascular Prevention, with or without Heterozygous Familial Hypercholesterolemia

Biomedicines, 2022
Background: Low-grade chronic inflammation, promoted by dysbiosis of the gut and oral microbiota, has been shown to contribute to individual susceptibility to atherosclerotic cardiovascular disease (ASCVD).
Maria Cristina Curia, Pamela Pignatelli, Domenica Lucia D’Antonio, Damiano D’Ardes, Elena Olmastroni, Luca Scorpiglione, Francesco Cipollone, Alberico Luigi Catapano, Adriano Piattelli, Marco Bucci, Paolo Magni   +10 more
doaj   +1 more source