Results 21 to 30 of about 339,685 (297)

Free fatty acids and cardiovascular outcome: a Chinese cohort study on stable coronary artery disease

Nutrition & Metabolism, 2017
Background Studies have revealed that plasma level of free fatty acids (FFAs) is related to cardiovascular disease. However, the role of FFAs in clinical outcomes of stable coronary artery disease (SCAD) has been less evaluated.
Hui-Wen Zhang, Xi Zhao, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Jing Sun, Geng Liu, Qian Dong, Jian-Jun Li   +8 more
doaj   +1 more source

Oral Porphyromonas gingivalis and Fusobacterium nucleatum Abundance in Subjects in Primary and Secondary Cardiovascular Prevention, with or without Heterozygous Familial Hypercholesterolemia

Biomedicines, 2022
Background: Low-grade chronic inflammation, promoted by dysbiosis of the gut and oral microbiota, has been shown to contribute to individual susceptibility to atherosclerotic cardiovascular disease (ASCVD).
Maria Cristina Curia, Pamela Pignatelli, Domenica Lucia D’Antonio, Damiano D’Ardes, Elena Olmastroni, Luca Scorpiglione, Francesco Cipollone, Alberico Luigi Catapano, Adriano Piattelli, Marco Bucci, Paolo Magni   +10 more
doaj   +1 more source

Clinical outcome of a patient with lysosomal acid lipase deficiency and first results after initiation of treatment with Sebelipase alfa: A case report [PDF]

, 2019
We report on a case of very rare autosomal recessive cholesteryl ester storage disease due to lysosomal acid lipase deficiency (LALD). LALD is caused by mutations in the lysosomal acid lipase A (LIPA) gene resulting in cholesteryl ester accumulation in
Bobbert, Thomas, Demuth, Ilja, Haberbosch, Linus, Hollstein, Tim, Kassner, Ursula, Soll, Dominik, Spira, Dominik, Spranger, Joachim, Steinhagen-Thiessen, Elisabeth   +8 more
core   +1 more source

Circulating PCSK9 and cardiovascular events in FH patients with standard lipid-lowering therapy

Journal of Translational Medicine, 2019
Background Proprotein convertase subtilisin/kexin 9 (PCSK9) has been proposed as a novel target for coronary artery disease (CAD). Familial hypercholesterolemia (FH) is characterized by high prevalence of CAD and major cardiovascular events (MACEs ...
Ye-Xuan Cao, Jing-Lu Jin, Di Sun, Hui-Hui Liu, Yuan-Lin Guo, Na-Qiong Wu, Rui-Xia Xu, Cheng-Gang Zhu, Qian Dong, Jing Sun, Jian-Jun Li   +10 more
doaj   +1 more source

Novel and traditional lipid-related biomarkers and their combinations in predicting coronary severity

Scientific Reports, 2017
We investigated simultaneously traditional and novel lipid indices, alone or in combination, in predicting coronary severity assessed by Gensini score (GS) in 1605 non-lipid-lowering-drug-treated patients undergoing coronary angiography.
Sha Li, Yuan-Lin Guo, Xi Zhao, Yan Zhang, Cheng-Gang Zhu, Na-Qiong Wu, Rui-Xia Xu, Ping Qing, Ying Gao, Xiao-Lin Li, Jing Sun, Geng Liu, Qian Dong, Jian-Jun Li   +13 more
doaj   +1 more source

Comparison of statin plus ezetimibe with double-dose statin on lipid profiles and inflammation markers

Lipids in Health and Disease, 2018
Background Achievement of low-density lipoprotein cholesterol (LDL-C) goal is the most important for the patients with atherosclerotic cardiovascular diseases (ASCVD) who received lipid-lowering therapy.
Na-Qiong Wu, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Xi Zhao, Di Sun, Jing Sun, Rui-Xia Xu, Geng Liu, Qian Dong, Jian-Jun Li   +10 more
doaj   +1 more source

Exploring metabolic dysfunction in chronic kidney disease [PDF]

, 2012
Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core   +2 more sources

Impact of free fatty acids on prognosis in coronary artery disease patients under different glucose metabolism status

Cardiovascular Diabetology, 2019
Background The aim of the present study is to examine the effects of free fatty acids (FFAs) on major cardiovascular events (MACEs) in patients with stable coronary artery disease (CAD) and different glucose metabolism status.
Jing-Lu Jin, Ye-Xuan Cao, Hui-Hui Liu, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Ying Gao, Jing Sun, Qian Dong, Jian-Jun Li   +11 more
doaj   +1 more source

Achievement of multiple therapeutic targets for cardiovascular disease prevention. Retrospective analysis of real practice in Italy [PDF]

, 2018
Background: Pharmacological therapy in patients at high cardiovascular (CV) risk should be tailored to achieve recommended therapeutic targets. Hypothesis: To evaluate individual global CV risk profile and to estimate the control rates of multiple ...
American Diabetes Association, Banegas, Bassand, Borghi, Conroy, Easton, Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults, Goldstein, Graham, Grundy, Grundy, Halcox, Kotseva, Mancia, Piepoli, Prugger, Rosengren, Rydén, Sakhuja, Sesti, Thygesen, Tocci, Tocci, Tocci, Tocci, Tocci, Tocci, Van de Werf, Volpe, Volpe, Volpe, Volpe, Whyte, Yusuf   +33 more
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Association of plasma free fatty acids levels with the presence and severity of coronary and carotid atherosclerotic plaque in patients with type 2 diabetes mellitus

BMC Endocrine Disorders, 2020
Background Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful marker for predicting ASCVD.
Ming-Hua Zhang, Ye-Xuan Cao, Li-Guo Wu, Na Guo, Bing-Jie Hou, Li-Jing Sun, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong, Jian-Jun Li   +9 more
doaj   +1 more source