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Influence of some cardiovascular risk factors on the rela-tionship between age and blood pressure [PDF]

NORDIC BALTIC CONFERENCE ON Biomedical Engineering and Medical Physics 2020, 2020
Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween BP and age changes with the presence of risk factors in hypertensive and normotensive subjects, we analyzed 880 ...
arxiv  

Smoking effect on the circadian rhythm of blood pressure in hypertensive subjects [PDF]

arXiv, 2020
The use of office measurement of Blood Pressure (BP) as well as of the mean on day-time, on night-time or on 24h does not accurately describe the changes of the BP circadian rhythm. Moreover, several risk factors affect this rhythm but until now possible alterations, due to the presence of such risk factors considered separately, were not been yet ...
arxiv  

Out-of-distribution Reject Option Method for Dataset Shift Problem in Early Disease Onset Prediction [PDF]

arXiv
Machine learning is increasingly used to predict lifestyle-related disease onset using health and medical data. However, the prediction effectiveness is hindered by dataset shift, which involves discrepancies in data distribution between the training and testing datasets, misclassifying out-of-distribution (OOD) data. To diminish dataset shift effects,
arxiv  

Nonparametric Estimation of Path-specific Effects in Presence of Nonignorable Missing Covariates [PDF]

arXiv
The path-specific effect (PSE) is of primary interest in mediation analysis when multiple intermediate variables between treatment and outcome are observed, as it can isolate the specific effect through each mediator, thus mitigating potential bias arising from other intermediate variables serving as mediator-outcome confounders.
arxiv  

Hypolipidemic effect of brown seaweed (Sargassum crassifolium) extract in vivo (Study of histopathology, mRNA expression, and immunohistochemistry (IHC) with VCAM-1, ICAM-1, and MCP-1 parameters) [PDF]

arXiv
The purpose of this study was to obtain natural drugs from brown seaweed (Sargassum crassifolium) as antiatherosclerosis candidates through the study of hypolipidemic mechanisms of action. Modeling of dyslipidemia rats was carried out by feeding high-fat (HFF) and doses of crude fucoidan 100. 200. 400mg / KgBB.
arxiv  

Machine learning predicts long-term mortality after acute myocardial infarction using systolic time intervals and routinely collected clinical data [PDF]

arXiv
Precise estimation of cardiac patients' current and future comorbidities is an important factor in prioritizing continuous physiological monitoring and new therapies. ML models have shown satisfactory performance in short-term mortality prediction of patients with heart disease, while their utility in long-term predictions is limited.
arxiv  

Diabetes Dyslipidemia [PDF]

Diabetes Therapy, 2016
Diabetes mellitus is associated with a considerably increased risk of premature atherosclerotic cardiovascular disease. Intensive glycemic control has essentially failed to significantly improve cardiovascular outcomes in clinical trials. Dyslipidemia is common in diabetes and there is strong evidence that cholesterol lowering improves cardiovascular ...
Schofield, Jonathan D, Liu, Yifen, Rao-Balakrishna, Prasanna, Malik, Rayaz A, Soran, Handrean   +4 more
openaire   +3 more sources

'Use of lipid-lowering therapy: the guidelines, the drugs or the patient?' [PDF]

, 2022
The current step up approach in the therapy of dyslipidemias aims to reduce the amount of LDL cholesterol below a threshold that varies according to the patient's risk category, with a pharmacological approach that sees statins as a fundamental ...
Borghi C., Bragagni A.
core   +1 more source

Familial hypercholesterolemia: The Italian Atherosclerosis Society Network (LIPIGEN) [PDF]

, 2017
Primary dyslipidemias are a heterogeneous group of disorders characterized by abnormal levels of circulating lipoproteins. Among them, familial hypercholesterolemia is the most common lipid disorder that predisposes for premature cardiovascular disease ...
Angelico, F., Arca, M, Averna, M., Bertolini, S, Calandra, S, Casula, M, Catapano, Al, Cefalù, Ab, Del Ben, M., Lipigen, Group, Maranghi, M, Montali, A., Noto, D, Tarugi, P.   +13 more
core   +1 more source

Exome sequencing in suspected monogenic dyslipidemias [PDF]

, 2015
Exome sequencing is a promising tool for gene mapping in Mendelian disorders.
Abifadel, M., AVERNA, Maurizio, Awan, Z., Boileau, C., CEFALU', Angelo Baldassare, Daly, M., Deo, R., Farlow, D., Fouchier, S., Freeman, M., Gabriel, S., Genest, J., Gupta, N., Haller, J., Hovingh, G., Kane, J., Kastelein, J., Kathiresan, S., Kawashiri, M., Larach, D., Mabuchi, H., Motazacker, M., Neale, B., Nickerson, D., Nohara, A., NOTO, Davide, Peloso, G., Pullinger, C., Rabès, J., Rader, D., Rich, S., Risman, M., Ruel, I., Shendure, J., Stitziel, N., Tada, H., Tarugi, P., Varret, M., Wilson, J., Yamagishi, M.   +39 more
core   +3 more sources