Results 141 to 150 of about 64,235 (269)

ENDOSCOPIC FINDINGS IN RELATION TO AGE AND SYMPTOMS IN PATIENTS PRESENTING WITH DYSPEPSIA

open access: yesPakistan Armed Forces Medical Journal, 2019
Objectives: To find the relative frequencies of different diseases causing dyspepsia, and to identify different diseases according to age. Study Design: Prospective cross-sectional study. Place and Duration of Study: Department of Gastroenterology,
laima Alam, Farrukh Saeed
doaj  

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim   +4 more
wiley   +1 more source

Fampridine for Symptomatic Treatment in Chronic Inflammatory Demyelinating Polyneuropathy: A Randomized, Double‐Blinded, Placebo‐Controlled Crossover Study

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 4, December 2026.
ABSTRACT Background and Aims Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is an immune‐mediated neuropathy that may cause persistent disability despite immunoglobulin treatment. Ion channel dysfunction has been demonstrated in CIDP, but no therapies specifically target this mechanism.
Peter Nørregaard Hansen   +5 more
wiley   +1 more source

An approach to a patient with dyspepsia.

open access: yes, 2004
Dyspepsia (indigestion) is a non-specific group symptoms related to the upper gastrointestinal tract. Organic disease must be detected and distinguished from non-"ulcer dyspepsia" or "functional" dyspepsia, so that specific treatment can be given ...
van Rensburg C.J.
core  

The Patient Concerns Inventory—Head and Neck (PCI‐HN): Swedish Translation and Cultural Adaptation

open access: yesScandinavian Journal of Caring Sciences, Volume 40, Issue 4, December 2026.
ABSTRACT Introduction The Patient Concerns Inventory—Head and Neck (PCI‐HN) is an item prompt list used in clinical settings to help patients with head and neck cancer (HNC) and their families address diagnosis, treatment, recovery and well‐being issues. The PCI‐HN has two versions: PCI‐HN AD (after diagnosis) and PCI‐HN PT (post‐treatment).
Ylva Tiblom Ehrsson   +5 more
wiley   +1 more source

Functional dyspepsia: recent advances in pathophysiology [PDF]

open access: yes, 1998
Functional (non-ulcer) dyspepsia is a common disease. With effective treatment now available for peptic ulcer; functional dyspepsia remains a major therapeutic challenge in gastrointestinal medicine. Despite advances in technology and diagnostic methods,
Lam, SK, Hu, HC
core  

Frequency of Clinically Relevant Drug–Drug Interactions Between Tyrosine Kinase Inhibitors and Proton Pump Inhibitors in Patients With Cancer Using Real‐World Data

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Background Proton pump inhibitors (PPIs) raise stomach pH, leading to reduced bioavailability of many tyrosine kinase inhibitors (TKIs), thereby affecting treatment outcomes. To what extent this interaction occurs in clinical practice remains underexplored.
Grietje van Elp   +5 more
wiley   +1 more source

Profile of Dyspepsia Patients in Mangusada Hospital

open access: yes
Dyspepsia is a common upper gastrointestinal disorder that may reduce patients’ quality of life. The high number of dyspepsia visits at Mangusada Regional General Hospital, Badung, throughout 2024 highlights the need to understand patient characteristics
Dewa Ayu Erica Fleury   +2 more
core   +1 more source

Artichoke Polyphenols Rich in 1,4‐Dicaffeoylquinic Acid Regulate Lipid Metabolism via the PPAR and AMPK Pathways to Alleviate Hepatic Lipid Accumulation

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Artichoke bract polyphenols, particularly from inner bracts, are rich in 1,4‐dicaffeoylquinic acid and chlorogenic acid. In oleic acid‐induced HepG2 cells, these polyphenols activate AMPK and modulate PPARγ signaling, reducing lipid accumulation. These findings highlight the potential of artichoke bracts, including agricultural waste outer bracts, as ...
Wenyang Tao   +7 more
wiley   +1 more source

A Comprehensive Review on Ferula oopoda (Boiss. and Buhse) Boiss.: Bioactive Compounds and Pharmacological Significance

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ferula oopoda (Boiss. and Buhse) Boiss.: bioactive compounds and pharmacological significance. ABSTRACT Ferula oopoda (Boiss. and Buhse) Boiss. is an ethnomedicinally important species widely used in Central and South Asia for the treatment of gastrointestinal, respiratory, neurological, and parasitic disorders.
Muhammad Ali   +5 more
wiley   +1 more source

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