Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide
ABSTRACT Aims Zenagamtide is a novel, unimolecular glucagon‐like peptide‐1 and amylin receptor agonist in development for weight management and Type 2 diabetes. This study investigated the pharmacokinetic (PK) properties, safety and tolerability of zenagamtide in participants with various degrees of renal impairment versus participants with normal ...
Lykke Ida Kaas Oldenburg +6 more
wiley +1 more source
Causal associations between human metabolites and functional dyspepsia: Evidence from two sample and multivariable Mendelian randomization. [PDF]
Long L, Li M, Liu L, Zhang L.
europepmc +1 more source
ABSTRACT Introduction Non‐endoscopic capsule sponge devices are a promising new technology. They could potentially improve oesophageal cancer outcomes by detecting and monitoring Barrett's oesophagus and identifying dysplasia early to allow timely treatment. Trials assessing their clinical utility are underway. Objective This study sought to understand
Ninian Schmeising‐Barnes +4 more
wiley +1 more source
MRI-Based Gastric Function Assessment in Patients With Functional Dyspepsia. [PDF]
Rosca V +9 more
europepmc +1 more source
A Systematic Review: Role of Pyloric Dilation in the Management of Gastroparesis
This systematic review highlights the clinical utility of pyloric dilation (PyD) across a range of populations with gastroparesis of varying severities. ABSTRACT Background Gastroparesis (GP) is a motility disorder characterized by pronounced delayed gastric emptying and associated with symptoms.
Milli Gupta +3 more
wiley +1 more source
Domperidone plus pinaverium bromide and itopride for functional dyspepsia in the elderly: efficacy, symptom improvement, and gastric function panel. [PDF]
Yang C +5 more
europepmc +1 more source
Anatomical and dynamic MRI performed before and after ingestion of a natural test meal provide complementary assessments of gastric accommodation, emptying, and regional wall kinematics. This integrated, noninvasive examination supports mechanistic phenotyping of gastric motor dysfunction in gastroparesis. ABSTRACT Background Gastroparesis is a complex
Xiaokai Wang +2 more
wiley +1 more source
Effectiveness and Safety of Herbal Decoctions for Functional Dyspepsia in Korean Medicine Clinics: A Multicenter Prospective Cohort Study Protocol. [PDF]
Park C, Ha NY, Kim J.
europepmc +1 more source
Paediatric Collagenous Gastritis with Transient Response to Steroid Therapy. [PDF]
O'Connor R +4 more
europepmc +1 more source
Methods and Techniques for Closed‐Loop Gastrointestinal Pacing
Closed‐loop gastrointestinal pacing continuously monitors electrical rhythm, detects dysrhythmia, delivers adaptive pacing, and verifies entrainment to restore normal electrical rhythm. ABSTRACT Purpose Gastrointestinal slow waves are rhythmic electrical events that contribute to the coordination of motility.
Chaveeka Weerakoon +4 more
wiley +1 more source

