Results 181 to 190 of about 59,437 (278)

Associations between psychological factors and functional dyspepsia symptoms with consideration of gender differences. [PDF]

Sci Rep
Volarić M, Babić E, Babič F, Bundzel M, Majnarić LT.   +4 more
europepmc   +1 more source

Tail-Suspension Model of Simulated Microgravity-Induced Functional Dyspepsia in Rats: Behavioral, Motility, and Brain-Gut Peptide Alterations. [PDF]

Int J Mol Sci
Li W, Li Y, Wang F, Qi H, Fan B, Wang G, Wang Q.   +6 more
europepmc   +1 more source

A Randomized, Double‐Blind, Placebo‐Controlled Phase 1 Study of Adiponectin Agonist (PEG)‐BHD1028 in People With Insulin Resistance

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Low adiponectin levels may contribute to insulin resistance. This first‐in‐human study evaluated adiponectin receptor agonist (PEG)‐BHD1028 in subjects with insulin resistance. Adults with BMI ≥ 27 kg/m2, HOMA‐IR ≥ 1.8, and HbA1c < 6.5% received subcutaneous injections of (PEG)‐BHD1028 or placebo in single‐ascending dose (SAD) cohorts (4, 8 ...
Pablo Lapuerta, Brian B. Kim
wiley   +1 more source

Functional dyspepsia overlapping with other functional gastrointestinal disorders: a bibliometric and visualization analysis. [PDF]

Front Med (Lausanne)
Fan M, Wang D, Yu K, Cai X, Cui J, Li F, Sun C, Wang A, Li Y, Liu Q.   +9 more
europepmc   +1 more source

Thorough QT/QTc Clinical Study to Evaluate the Effect of Remdesivir on Cardiac Repolarization in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT QT interval prolongation associated with drug administration is an important consideration in drug development. Patients with COVID‐19 are at increased risk for cardiac complications, and QT interval prolongation correlates with higher mortality.
Chi‐Chi Peng, Ran Duan, Mazin Abdelghany, Santosh Davies, Deqing Xiao, Anna Kwan, Ana Ruiz‐Garcia   +6 more
wiley   +1 more source

Burden and Predictors of Repeat Diagnostic Upper Endoscopy for Abdominal Pain, Heartburn, and Dysphagia in General Gastroenterology. [PDF]

Dig Dis Sci
Kathuria P, Shah ED.
europepmc   +1 more source

Efficacy and Safety of Fixed‐Dose Combinations of Sitagliptin and Empagliflozin as Add‐On to Metformin in Korean Patients With Type 2 Diabetes: A Randomised, Double‐Blind, Multi‐Centre, Placebo‐Controlled, Phase III Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4847-4859, June 2026.
ABSTRACT Background Type 2 diabetes mellitus (T2DM) is a progressive, multi‐organ disorder that often requires intensive combination therapy. This Phase III, randomised, double‐blind, placebo‐controlled study evaluated the efficacy and safety of two fixed‐dose combinations (FDCs) of sitagliptin 100 mg with empagliflozin 10 mg (DW1026C1) or ...
Soo Lim, Tae Nyun Kim, Ji Oh Mok, Choon Hee Chung, You Cheol Hwang, Ho Chan Cho, Jong Chul Won, Eonju Jeon, Eun Seok Kang, Ki Young Lee, Chong Hwa Kim, Soo Heon Kwak, Cheol Young Park, Kang Seo Park, Sang Yong Kim, Jae Hyuk Lee, Soon Hee Lee, Dong Hyeok Cho, Hyuk‐Sang Kwon, Kyung Ah Han   +19 more
wiley   +1 more source

Duodenal microbiota profiling and its effects on gastrointestinal tract dysfunction. [PDF]

Front Cell Infect Microbiol
Sohrabi A, Sadeghi F, Zagai U, Andreasson A, Vieth M, Agréus L, Talley NJ, Ye W.   +7 more
europepmc   +1 more source

Downstream Treatment Burden and Health‐Care Utilization Following Initiation of GLP‐1 Receptor Agonists or SGLT2 Inhibitors in Type 2 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5163-5173, June 2026.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and sodium–glucose cotransporter 2 (SGLT2) inhibitors are widely used for the treatment of type 2 diabetes, yet their downstream consequences in routine clinical practice remain incompletely characterized.
Yazan Alhamdan, Jason C. Hsu, Christine Y. Lu   +2 more
wiley   +1 more source

Appropriate prescribing and deprescribing of proton pump inhibitors: New Choosing Wisely Canada toolkit. [PDF]

Can Fam Physician
Bland E, van Zanten SV, Thompson W.
europepmc   +1 more source