Results 121 to 130 of about 40,558 (343)

Long‐Term Safety and Efficacy of Repeat Treatments with DaxibotulinumtoxinA in Cervical Dystonia: Results from the ASPEN‐Open‐Label Study

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background DaxibotulinumtoxinA (DAXI), a novel botulinum neurotoxin (BoNT) formulation, was shown to be safe, effective, and long‐lasting in the treatment of cervical dystonia (CD) over one treatment cycle in the phase 3, randomized, placebo‐controlled ASPEN‐1 trial.
Peter McAllister, Atul T. Patel, Marta Banach, Aaron Ellenbogen, Jaroslaw Slawek, Sebastian Paus, Hyder A. Jinnah, Virgilio Evidente, Todd M. Gross, Rashid Kazerooni, Conor J. Gallagher, David A. Hollander   +11 more
wiley   +1 more source

Subjective Well‐Being and Its Predictors in Parkinson's Disease and Dystonia: A Comparative Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Quality of life (QoL) is a commonly used outcome measure in people with chronic neurological diseases (CND). As valuable as QoL is, it does not take into account aspects of subjective well‐being (SWB) such as subjective happiness, meaning in life, life satisfaction and hope; all constructs that are considered central to well‐being ...
Suzette Shahmoon, Dejan Georgiev, Paul Jarman, Kailash Bhatia, Patricia Limousin, Marjan Jahanshahi   +5 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Does Early Laser Treatment of Capillary Malformations Lead to More Favorable Outcomes?

The Laryngoscope, EarlyView.
Larkin Harris, Reema Padia
wiley   +1 more source

Structural Alterations in the Gray Matter Volume in Rapid‐Onset Dystonia‐Parkinsonism

Movement Disorders, EarlyView.
Abstract Background Previously, we identified decreased thalamic blood flow in patients with ATP1A3 variants. Objective This study evaluated structural gray matter organization in rapid‐onset dystonia‐parkinsonism (RDP) patients compared with controls and two phenotypically overlapping movement disorders.
Ihtsham U. Haq, Kristina Simonyan, Eleonora Napoli, Laurie J. Ozelius, Beverly M. Snively, Christopher T. Whitlow, Kathleen J. Sweadner, Allison Brashear   +7 more
wiley   +1 more source

Somato‐Cognitive Action Network in Focal Dystonia

Movement Disorders, EarlyView.
Abstract Background The central pathology causing idiopathic focal dystonia remains unclear. The recently identified somato‐cognitive action network (SCAN) has been implicated. Objective We tested whether the effector‐agnostic SCAN may constitute a central pathology shared across dystonia subtypes, whereas the effector‐specific regions in the primary ...
Yuchao Wang, Baothy Huynh, Jianxun Ren, Mo Chen, Wei Zhang, Dan Hu, Shasha Li, Hesheng Liu, Teresa J. Kimberley   +8 more
wiley   +1 more source

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

Movement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger, Chi Wang Ip   +1 more
wiley   +1 more source

Effects of Hypothyroidism on the Extracellular Matrix of the Vocal Folds of Adult Female Rats

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The aim of the present study was to investigate the changes in the extracellular matrix of the vocal folds of female rats after induction of hypothyroidism. Study Design Prospective and experimental study. Setting Single tertiary center.
Welber C. Mororó, Karine V. G. de Oliveira, Jônatas B. do Amaral, Gisele Giannocco, João R. M. Martins, Noemi G. De Biase   +5 more
wiley   +1 more source

Artificial Intelligence Models for Dysphonia Patient Education

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Evaluate and compare artificial intelligence (AI) chatbot responses to queries extrapolated from statements by Dysphonia International (DI). Study Design Cross‐sectional analysis. Setting Online using ChatGPT, Google AI Overview (GAO), and DI.
Rebecca An Ho, Esha Shah, John Sebastian De Armas, Kenneth Yan, Rachel Kaye   +4 more
wiley   +1 more source

Prevalence of Speech and Swallowing Dysfunction and Intervention Among Individuals With Myasthenia Gravis

OTO Open
Objective To examine the prevalence of dysphonia and dysphagia among individuals with myasthenia gravis (MG) and the frequency of utilization of speech and swallow evaluation and therapy. Study Design Retrospective cohort study.
Tyler J. Gallagher, Chloe Santa Maria, Michael M. Johns   +2 more
doaj   +1 more source