Results 131 to 140 of about 367,278 (369)
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background Ionizing radiation (IR) is a standard modality for the management of solid tumors. Apart from its killing effects, IR can induce pro‐survival factors leading to radioresistance of cancer. Mechanistic understanding of radiation resistance is warranted to overcome the pro‐survival effects of IR.
Seema Gupta, Mansoor M. Ahmed
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Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, EarlyView.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
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Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry. [PDF]
, 2019 Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing upper endoscopy during
Berzin, T +47 more
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Screening Relevance of Sessile Serrated Polyps [PDF]
, 2019 Conventional adenomas have historically been considered to be the only screening-relevant colorectal cancer (CRC) precursor lesion. The prevailing paradigm was that most CRCs arise along the chromosomal instability pathway, where adenomas accumulate ...
Kahi, Charles J.
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Clonal Hematopoiesis and Thrombosis
American Journal of Hematology, EarlyView.ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
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High doses of zoledronic acid induce differential effects on femur and jawbone microstructure
Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1487-1495, December 2022., 2022 Abstract Objectives The aim of this study is to investigate the long‐term effects on jaw and femur bone induced by oncologic doses of zoledronic acid in a young rat model. Material and Methods Six 12‐week‐old male Wistar rats received zoledronic acid (0.6 mg/kg) and six control rats received saline solution in the same volume.
Mariana Q. S. Soares +7 more
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The pathologists’ eyes on foregut: histopathological relations in the experimental and routine diagnostics [PDF]
, 2011 SUMMARY I. The study aimed to investigate the incidence of duodeno-gastroesophageal reflux-induced malignoma formation in a series of duodeno-esophageal anastomosis operations in rats.
Németh István Balázs
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Molecular testing of soft tissue tumors
Diagnostic Cytopathology, Volume 51, Issue 1, Page 12-25, January 2023., 2023 Abstract Background The diagnosis of soft tissue tumors is challenging, especially when the evaluable material procured is limited. As a result, diagnostic ancillary testing is frequently needed. Moreover, there is a trend in soft tissue pathology toward increasing use of molecular results for tumor classification and prognostication. Hence, diagnosing
Douglas Rottmann +2 more
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Revista Cubana de Medicina, 2005 El desarrollo del cáncer colorrectal en pacientes con colitis ulcerativa idiopática guarda estrecha relación con el tiempo de evolución de la enfermedad (más de 10 años) y la extensión de esta (universal).
Manuel Paniagua Estévez +4 more
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