Results 51 to 60 of about 228,263 (297)

Significance of intestinal metaplasia and dysplasia in morphological diagnosis of patients with chronic reflux gastritis

open access: yesGastroenterologìa, 2017
The present study was undertaken to analyze biopsies in 120 cases of chronic reflux gastritis with the help of modern histological, histochemical and morphometric methods.
Yu.M. Stepanov   +2 more
doaj   +1 more source

Use of Reticulated Hyaluronic Acid Alone or Associated With Ozone Gas in the Treatment of Osteoarthritis Due to Hip Dysplasia in Dogs

open access: yesFrontiers in Veterinary Science, 2020
This study aimed to evaluate reticulated hyaluronic acid alone or associated with ozone gas in the treatment of osteoarthritis due to hip dysplasia in dogs. Fourteen client-owned dogs were randomly assigned into two groups: Group 1—single intra-articular
José I. S. Silva Júnior   +7 more
doaj   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen   +14 more
wiley   +1 more source

A Study of Skeletal Stem Cell Dynamics and Its Potential Applications in the Design of a Titanium Implant for Senile Osteoporosis

open access: yesAdvanced Science, EarlyView.
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan   +12 more
wiley   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

open access: yesAdvanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan   +13 more
wiley   +1 more source

Osteogenesis Imperfecta: A study of the patient journey in 13 European countries

open access: yesOrphanet Journal of Rare Diseases
Introduction Osteogenesis imperfecta (OI) is a heritable skeletal disorder and comprises various subtypes that differ in clinical presentation, with Type I considered the least severe and Types III/IV the most severe forms.
Ingunn Westerheim   +4 more
doaj   +1 more source

Adénome de la vésicule biliaire avec aspect cholestérolose

open access: yesThe Pan African Medical Journal, 2016
L'adénome de la vésicule biliaire est une tumeur bénigne souvent asymptomatique, découverte dans 0,5% des pièces de cholécystectomie. Nous présentons le cas d'une femme de 79 ans, admise pour suspicion de pancréatite aiguë d'origine lithiasique.
Ben Slama Sana, Khadhar Aida
doaj   +1 more source

Minimally Invasive Bowel Cancer Detection through Vibrating Microrobot‐Induced Elastography

open access: yesAdvanced Intelligent Systems, EarlyView.
A minimally invasive diagnostic method for bowel cancer detection combines vibrating microrobots and laser speckle contrast imaging to map tissue elasticity. By analyzing vibration‐induced resonance, detailed elasticity maps are produced, clearly differentiating tumors from healthy tissue.
Andrew Bickerdike   +3 more
wiley   +1 more source

Phenotypic Characterization of Seven Pediatric Patients Diagnosed With KAT6B‐Related Disorders: Case Series and Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione   +12 more
wiley   +1 more source

Optimizing ventilator support in severe bronchopulmonary dysplasia in the absence of conclusive evidence

open access: yesFrontiers in Pediatrics, 2022
Audrey N. Miller   +9 more
doaj   +1 more source

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