Results 51 to 60 of about 271,809 (300)

Prevalence of Acute Dyspnea among College-going Regular Smokers in North India: A Survey Study

open access: yesJournal of the Scientific Society
Contexts: Smoking remains the leading cause of preventable death globally, impacting health. Aims: This study aimed to investigate the prevalence of regular smokers experiencing acute dyspnea among college students in North India.
Abhishek Shrestha   +3 more
doaj   +1 more source

Predictors of health status do not change over three-year periods and exacerbation makes difference in chronic obstructive pulmonary disease

open access: yesHealth and Quality of Life Outcomes, 2011
Background The association between disease markers and health status (HS) overtime is unclear. The aim of this study was to verify the predictors of HS at baseline and after three years in Chronic Obstructive Pulmonary Disease (COPD) patients.
Ferrari Renata   +4 more
doaj   +1 more source

Dyspnea

open access: yes, 2017
This chapter provides an overview of the prevalence, pathophysiology, assessment, and clinical management of dyspnea, also known as shortness of breath or air hunger.
Kathleen Broglio
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Exercise capacity, dyspnea, and quality of life 6 months after exercise-based rehabilitation in patients with persistent dyspnea following pulmonary embolism

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Exercise is safe and effective in the short-term following pulmonary embolism. To date, little is known about the long-term effects. Objectives: The aim of the study was to investigate whether the effects of exercise-based rehabilitation are ...
Stacey Haukeland-Parker   +12 more
doaj   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

open access: yesAdvanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin   +5 more
wiley   +1 more source

Dysphagia and Dyspnea Caused by Large Anterior Cervical Osteophyte

open access: yesEgyptian Spine Journal, 2019
Background Data: Unfortunately, large anterior cervical osteophytes are a forgotten cause of dysphagia and dyspnea. They can cause marked change in diet habits or interfere with patients’ daily activities and sleep without significant neck pain or ...
Ashraf S Zidan, MD.   +2 more
doaj   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu   +14 more
wiley   +1 more source

Cardiopulmonary exercise testing in the assessment of exertional dyspnea

open access: yesAnnals of Thoracic Medicine, 2015
Dyspnea on exertion is a commonly encountered problem in clinical practice. It is usually investigated by resting tests such as pulmonary function tests and echocardiogram, which may at times can be non-diagnostic. Cardiopulmonary exercise testing (CPET)
Debapriya Datta   +2 more
doaj   +1 more source

Neural gating during exercise-induced dyspnea

open access: yes, 2022
According to the neural gating model of respiratory sensations, dyspnea is the result of a reduced filtering out (“gating out”) of respiratory sensations into the cerebral cortex.
Prof. Andreas von Leupoldt   +7 more
core   +1 more source

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