Results 91 to 100 of about 10,837 (204)

Unveiled SOX2 disorder in a child initially diagnosed as cerebral palsy

Egyptian Journal of Medical Human Genetics
Background SOX2 disorder is a genetic disorder caused by disease-causing variants of the SOX2 located on chromosome 3q26.3-q27.1. SOX2 disorder is clinically characterized by severe eye malformations but is also associated with developmental delay ...
Hanee Rim, Jaewon Kim, Myungshin Kim, Jaewoong Lee, Dae-Hyun Jang   +4 more
doaj   +1 more source

Bradykinesia in dystonic hand tremor: kinematic analysis and clinical rating

Frontiers in Human Neuroscience
IntroductionBradykinesia is an essential diagnostic criterion for Parkinson’s disease (PD) but is frequently observed in many non-parkinsonian movement disorders, complicating differential diagnosis, particularly in disorders featuring tremors.
Peter Matejicka, Slavomir Kajan, Jozef Goga, Igor Straka, Marek Balaz, Marek Balaz, Simon Janovic, Michal Minar, Peter Valkovic, Peter Valkovic, Michal Hajduk, Michal Hajduk, Michal Hajduk, Zuzana Kosutzka   +13 more
doaj   +1 more source

Beyond the Homunculus—SCAN‐AMN as a Shared Action‐Oriented Neural Substrate across Movement Disorders

Movement Disorders, EarlyView.
Arjun Balachandar, Alvaro Hernandez‐Guillen, Nico U.F. Dosenbach, Anthony E. Lang, Christos Ganos   +4 more
wiley   +1 more source

Phenotypic characteristics of paroxysmal dyskinesia in 25 cats

Journal of Small Animal Practice, EarlyView.
Objectives Paroxysmal dyskinesia has, to date, been reported only systematically in Sphynx cats. This study aims to describe paroxysmal dyskinesia in additional breeds. Materials and Methods The medical records of cats from multiple hospitals presenting with episodes consistent with paroxysmal dyskinesia between 2020 and 2025 were retrospectively ...
T. Liatis, C. Maeso, A. De Stefani, A. Pergande, T. Elvira, A. Suñol   +5 more
wiley   +1 more source

‘Taking the green pill’: An interpretative phenomenological analysis of the lived experiences of climate distress

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Introduction Climate distress (CD) is an emerging psychological response to the climate crisis, encompassing anxiety, grief, shame, and helplessness. While empirical research has begun to explore its prevalence and emotional impacts, little is known about the lived experience of CD.
Jessica L. Morgan, James D. Gregory, Marc O. Williams   +2 more
wiley   +1 more source

Olfactory dysfunction as a diagnostic and prognostic marker for movement disorders

Annals of Movement Disorders
Olfactory dysfunction (OD) is a common nonmotor symptom observed in several movement disorders. The severity and pattern of olfactory impairment vary among these conditions.
Aliasghar Peyvandi, Shahrokh Khoshsirat, Narges Bazgir, Amirreza Zaker, Azin Tahvildari, Somayeh Niknazar, Sara Mohammadi, Mehri Salari   +7 more
doaj   +1 more source

Steady‐state Purkinje cell activity has limited predictive power for cerebellar output in disease

The Journal of Physiology, EarlyView.
Abstract figure legend Cerebellar dysfunction can give rise to various movement disorders. Misfiring cerebellar neurons often underlie this dysfunction. Because Purkinje cells form inhibitory synapses onto cerebellar nuclei cells, it has been presumed that spike activity changes in Purkinje cells cause inverse spike activity changes in the downstream ...
Alyssa M Lyon, Viviana Hernandez‐Castanon, Meike E van der Heijden   +2 more
wiley   +1 more source

Combination Versus Monotherapy in Acute Anti‐LGI1 Encephalitis: A Real‐World Dose Optimization Analysis

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Combined IVIg and 500 mg/day IVMP achieve superior efficacy over monotherapies in anti‐LGI1 encephalitis, with optimal safety. Higher‐dose IVMP (1000 mg) accelerates response but increases adverse events, particularly in diabetic patients. Cognitive deficits persist post‐treatment, necessitating long‐term management.
Yao Tan, Ming Sun, Qinqin Liu, Beibei Huang, Chao Wu, Jie Lu, Donglin Zhu   +6 more
wiley   +1 more source

Collaborative Genomics for Dystonia in Central and Eastern Europe: Successes Achieved, New Frontiers Ahead

Movement Disorders, EarlyView.
Robert Jech, Petra Havránková, Eugenia Tsoma, Lukáš Kunc, Tomáš Krajča, Ján Necpál, Olga Ulmanová, Aleksandra Tomic, Ivana Dzinovic, Irena Rektorová, Marek Baláž, Tereza Serranová, Stanislava Jaselska, Maria Giertlova, Kristina Kulcsarova, Alexandra Lackova, Denisa Harvanova, Miriam Ostrozovicova, Vladimir Han, GenDy Collaborators, Matej Škorvánek, Michael Zech   +21 more
wiley   +1 more source

Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia

Annals of Neurology, Volume 99, Issue 5, Page 1227-1238, May 2026.
Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani, Shiro Horisawa, Konstantin Butenko, Hiroki Togo, Arun Garimella, William Drew, Melissa Chua, Esraa Shaban, Takakazu Kawamata, Takaomi Taira, Andreas Horn, Michael D. Fox, Takashi Hanakawa   +12 more
wiley   +1 more source