Results 81 to 90 of about 1,792 (176)
Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation [PDF]
, 2014 Phosphorylation by the cyclin-dependent kinase 1 (Cdk1) adjacent to nuclear localization signals (NLSs) is an important mechanism of regulation of nucleocytoplasmic transport. However, no systematic survey has yet been performed in human cells to analyze
Bodaen, Mikael +13 more
core +2 more sources
JAK Inhibitors for Pemphigoid Diseases
Dermatologic Therapy, Volume 2025, Issue 1, 2025.Pemphigoid diseases are a group of chronic autoimmune blistering skin disorders, with bullous pemphigoid representing the most prevalent subtype. Bullous pemphigoid (BP) primarily affects individuals aged 60–80 years, and its incidence has been steadily rising in correlation with increasing life expectancy and population aging in Western countries ...
Enkhbilguun Sodbuyan +3 more
wiley +1 more source
Tegument Assembly and Secondary Envelopment of Alphaherpesviruses. [PDF]
, 2015 Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their ability to establish lifelong latent infection in neurons. As for all herpesviruses, alphaherpesvirus virions contain a protein-rich layer called "tegument" that ...
Crump, Colin M +2 more
core +3 more sources
Molecular Genetics &Genomic Medicine, Volume 12, Issue 10, October 2024.We revealed a genetic link between atopic dermatitis and bullous pemphigoid, which is associated with biological pleiotropy and causality. Awareness of the association between BP and AD helps dermatologists manage patients with these illnesses. ABSTRACT Background Bullous pemphigoid (BP) and atopic dermatitis (AD) are currently thought to be tightly ...
Qing Wang +9 more
wiley +1 more source
ショウジョウバエを用いた統合失調症リスク遺伝子Disrupted-in- Schizophrenia 1の分子遺伝学的解析 [PDF]
, 2016 この博士論文は内容の要約のみの公開（または一部非公開）になっています筑波大学 (University of Tsukuba ...
KURITA Kazuki, 栗田 一輝
core
Aging Cell, Volume 23, Issue 4, April 2024.The skin fulfills vital functions for humans. Its protective barrier function is provided by the epidermis, which is constantly renewed thanks to the presence of progenitor cells that are firmly attached to the underlying basement membrane and whose proliferation and differentiation give it a typical undulating topography.
Eva Roig‐Rosello +5 more
wiley +1 more source
mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft [PDF]
, 2008 Background Interactions between the gene products encoded by the mitochondrial and nuclear genomes play critical roles in eukaryotic cellular function. However, the effects mitochondrial DNA (mtDNA) levels have on the nuclear transcriptome have not been ...
Darren Magda +9 more
core +1 more source
Low expression of TGF‐β2 and matrilin2 in human aqueous humour with acute primary angle closure
Journal of Cellular and Molecular Medicine, Volume 28, Issue 3, February 2024.Abstract Primary angle‐closure glaucoma (PACG) is the leading cause of irreversible blindness in the world. Angle closure induced by pupil block and secondary iris synechia is the fundamental pathology of the PACG. The molecular mechanisms of angle closure have not yet been clearly illustrated.
Liming Wang +11 more
wiley +1 more source
Pemfigoidin komorbiditeetit, kliininen kuva ja lääkehoito : retrospektiivinen tutkimus HYKS:issä [PDF]
, 2016 Tutkimuksen tavoitteena oli kartoittaa pemfigoidiin liittyviä edeltäviä sairauksia ja lääkityksiä suomalaisessa potilasotoksessa. Pohjoiseurooppalaisia tutkimuksia aiheesta ei ole tehty.
Pankakoski, Anna
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Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source